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Cole-Parmer
Cole-Parmer Instrument Company, now known as Antylia Scientific. The company serves professionals in biopharma, environmental and life sciences. History The company was founded by Jerry Cole and John Parmer in 1955 and took up shop in a loft on West Illinois Street in downtown Chicago. In the 1960s, Cole-Parmer acquired Masterflex peristaltic pumps, followed shortly by the purchases of Gilmont Instruments and Manostat Pumps. They were acquired by Fisher Scientific, now Thermo-Fisher Scientific, in 2001. On July 17, 2014, Thermo Fisher Scientific Inc. Thermo Fisher Scientific Inc. is an American supplier of scientific instrumentation, reagents and consumables, and software services. Based in Waltham, Massachusetts, Thermo Fisher was formed through the merger of Thermo Electron and Fisher Sci ... agreed to sell one of its lab units, Cole-Parmer, to private-equity firm GTCR for $480 million in cash. The company has previously said its $13.6 billion acquisition of Life Tech ...
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Vernon Hills, Illinois
Vernon Hills is a suburb north of Chicago, Illinois in Lake County, Illinois, Lake County, Illinois, United States. The population was 26,850 at the 2020 census. Vernon Hills serves as a retail hub for its surrounding area (Libertyville, Illinois, Libertyville, Lake Forest, Illinois, Lake Forest, Long Grove, Illinois, Long Grove, Lincolnshire, Illinois, Lincolnshire and Buffalo Grove, Illinois, Buffalo Grove). History The land that was to become Vernon Hills, founded by Richard Theodore Freese, Ron Freese, and Jim Carswell, began with the establishment of a farm in 1857. Use of the land remained relatively static until the 1960s, when part of it was purchased for a residential community and golf course; the development was the first use of the name "Vernon Hills." On June 16, 1958, the village officially incorporated with 123 residents and 125 houses in a single subdivision built by Quinn Hogan and Barney Loeb. During these times, the village and police department were run from ...
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Centrifuges
A centrifuge is a device that uses centrifugal force to separate various components of a fluid. This is achieved by spinning the fluid at high speed within a container, thereby separating fluids of different densities (e.g. cream from milk) or liquids from solids. It works by causing denser substances and particles to move outward in the radial direction. At the same time, objects that are less dense are displaced and moved to the centre. In a laboratory centrifuge that uses sample tubes, the radial acceleration causes denser particles to settle to the bottom of the tube, while low-density substances rise to the top. A centrifuge can be a very effective filter that separates contaminants from the main body of fluid. Industrial scale centrifuges are commonly used in manufacturing and waste processing to sediment suspended solids, or to separate immiscible liquids. An example is the cream separator found in dairies. Very high speed centrifuges and ultracentrifuges able to provid ...
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Burettes
A burette is a graduated glass tube with a tap at one end, for delivering known volumes of a liquid, especially in titrations. It is a long, graduated glass tube, with a stopcock at its lower end and a tapered capillary tube at the stopcock's outlet. The flow of liquid from the tube to the burette tip is controlled by the stopcock valve. There are two main types of burette; the volumetric burette and the piston burette. A volumetric burette delivers measured volumes of liquid. Piston burettes are similar to syringes, but with a precision bore and a plunger. Piston burettes may be manually operated or may be motorized. A weight burette delivers measured weights of a liquid. Overview A burette is a volumetric measuring glassware which is used in analytical chemistry for the accurate dispensing of a liquid, especially of one of the reagents in a titration. The burette tube carries graduated marks from which the dispensed volume of the liquid can be determined. Compared to a volumetr ...
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Calorimeters
A calorimeter is an object used for calorimetry, or the process of measuring the heat of chemical reactions or physical changes as well as heat capacity. Differential scanning calorimeters, isothermal micro calorimeters, titration calorimeters and accelerated rate calorimeters are among the most common types. A simple calorimeter just consists of a thermometer attached to a metal container full of water suspended above a combustion chamber. It is one of the measurement devices used in the study of thermodynamics, chemistry, and biochemistry. To find the enthalpy change per mole of a substance A in a reaction between two substances A and B, the substances are separately added to a calorimeter and the initial and final temperatures (before the reaction has started and after it has finished) are noted. Multiplying the temperature change by the mass and specific heat capacities of the substances gives a value for the energy given off or absorbed during the reaction. Dividing the ...
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Chromatography
In chemical analysis, chromatography is a laboratory technique for the separation of a mixture into its components. The mixture is dissolved in a fluid solvent (gas or liquid) called the ''mobile phase'', which carries it through a system (a column, a capillary tube, a plate, or a sheet) on which a material called the ''stationary phase'' is fixed. Because the different constituents of the mixture tend to have different affinities for the stationary phase and are retained for different lengths of time depending on their interactions with its surface sites, the constituents travel at different apparent velocities in the mobile fluid, causing them to separate. The separation is based on the differential partitioning between the mobile and the stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation. Chromatography may be preparative or analytical. The purpose of preparativ ...
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Electrophoresis
Electrophoresis, from Ancient Greek ἤλεκτρον (ḗlektron, "amber") and φόρησις (phórēsis, "the act of bearing"), is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric field. Electrophoresis of positively charged particles (cations) is sometimes called cataphoresis, while electrophoresis of negatively charged particles (anions) is sometimes called anaphoresis. The electrokinetic phenomenon of electrophoresis was observed for the first time in 1807 by Russian professors Peter Ivanovich Strakhov and Ferdinand Frederic Reuss at Moscow University, who noticed that the application of a constant electric field caused clay particles dispersed in water to migrate. It is ultimately caused by the presence of a charged interface between the particle surface and the surrounding fluid. It is the basis for analytical techniques used in chemistry for separating molecules by size, charge, or binding affinity. Electropho ...
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Electroporation
Electroporation, or electropermeabilization, is a microbiology technique in which an electrical field is applied to cells in order to increase the permeability of the cell membrane, allowing chemicals, drugs, electrode arrays or DNA to be introduced into the cell (also called electrotransfer). In microbiology, the process of electroporation is often used to transform bacteria, yeast, or plant protoplasts by introducing new coding DNA. If bacteria and plasmids are mixed together, the plasmids can be transferred into the bacteria after electroporation, though depending on what is being transferred, cell-penetrating peptides or CellSqueeze could also be used. Electroporation works by passing thousands of volts (~8 kV/cm) across suspended cells in an electroporation cuvette. Afterwards, the cells have to be handled carefully until they have had a chance to divide, producing new cells that contain reproduced plasmids. This process is approximately ten times more effective in increasing ...
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Freeze Dryers
Freeze may refer to: Liquids turning to solids * Freezing, the physical process of a liquid turning into a solid * Directional freezing, freezing from only one direction or side Cessation of movement or change *Freeze (b-boy move), the halting of all movement in a clever position * freeze, an old command-line compressor program *Freeze (computing), a condition when computer software becomes unresponsive *Freeze (software engineering), a period of stricter rules for changing the software during its development Types of freezes * Brain freeze, a common alternate name for a cold-stimulus headache * Budget freeze, when a budget for a government or business is held at a specific level * Credit freeze, the act of locking data at a consumer reporting agency * Deep Freeze (other), various meanings * Estate freeze, a legal estate-planning technique used in Canada *Nuclear freeze, an agreement to cease production of new nuclear arms * Tuition freeze, a government policy res ...
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Histology
Histology, also known as microscopic anatomy or microanatomy, is the branch of biology which studies the microscopic anatomy of biological tissues. Histology is the microscopic counterpart to gross anatomy, which looks at larger structures visible without a microscope. Although one may divide microscopic anatomy into ''organology'', the study of organs, ''histology'', the study of tissues, and ''cytology'', the study of cells, modern usage places all of these topics under the field of histology. In medicine, histopathology is the branch of histology that includes the microscopic identification and study of diseased tissue. In the field of paleontology, the term paleohistology refers to the histology of fossil organisms. Biological tissues Animal tissue classification There are four basic types of animal tissues: muscle tissue, nervous tissue, connective tissue, and epithelial tissue. All animal tissues are considered to be subtypes of these four principal tissue types ...
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Titrators
Titration (also known as titrimetry and volumetric analysis) is a common laboratory method of quantitative chemical analysis to determine the concentration of an identified analyte (a substance to be analyzed). A reagent, termed the ''titrant'' or ''titrator'', is prepared as a standard solution of known concentration and volume. The titrant reacts with a solution of ''analyte'' (which may also be termed the ''titrand'') to determine the analyte's concentration. The volume of titrant that reacted with the analyte is termed the ''titration volume''. History and etymology The word "titration" descends from the French word ''titrer'' (1543), meaning the proportion of gold or silver in coins or in works of gold or silver; i.e., a measure of fineness or purity. ''Tiltre'' became ''titre'', which thus came to mean the "fineness of alloyed gold", and then the "concentration of a substance in a given sample". In 1828, the French chemist Joseph Louis Gay-Lussac first used ''titre'' as ...
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Thermo Fisher Scientific Inc
Thermo Fisher Scientific Inc. is an American supplier of scientific instrumentation, reagents and consumables, and software services. Based in Waltham, Massachusetts, Thermo Fisher was formed through the merger of Thermo Electron and Fisher Scientific in 2006. Thermo Fisher Scientific has acquired other reagent, consumable, instrumentation, and service providers, including: Life Technologies Corporation (2013), Alfa Aesar (2015), Affymetrix (2016), FEI Company (2016), BD Advanced Bioprocessing (2018), and PPD (2021). As of 2017, the company had a market capitalization of $21 billion and was a Fortune 500 company. Annual revenue in 2021 was US$39.21 billion. In March 2020, Thermo Fisher Scientific received emergency use authorization from the FDA for a test for SARS-CoV-2 to help mitigate the COVID-19 pandemic. History Predecessors and merger Thermo Electron was co-founded in 1956 by George N. Hatsopoulos and Peter M Nomikos. Hatsopoulos received a PhD from MIT in ...
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