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Closed System Drug Transfer Device
A closed system drug transfer device or "CSTD" is a drug transfer device that mechanically prohibits the transfer of environmental contaminants into a system and the escape of hazardous drug or vapor concentrations outside the system. Open versus closed systems are commonly applied in medical devices to maintain the sterility of a fluid pathway. CSTDs work by preventing the uncontrolled inflow and outflow of contaminants and drugs, preserving the quality of solution to be infused into a patient. Theoretically, CSTDs should enable complete protection to healthcare workers in managing hazardous drugs, but possibly due to improper handling or incomplete product design, contaminants can still be detected despite use of CSTDs. Medical use Hazardous drugs are often used for patients with cancer. For example, chemotherapy agents are routinely used in the treatment of cancer. However, chemotherapy can be dangerous to a person even if they don't have cancer, as chemotherapy often indiscrimina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cochrane Review
Cochrane (previously known as the Cochrane Collaboration) is a British international charitable organisation formed to organise medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. It includes 53 review groups that are based at research institutions worldwide. Cochrane has approximately 30,000 volunteer experts from around the world. The group conducts systematic reviews of health-care interventions and diagnostic tests and publishes them in the Cochrane Library. According to the Library, articles are available via one-click access, but some require paid subscription or registration before reading. A few reviews, in occupational health for example, incorporate results from non-randomised observational studies as well as controlled before–after (CBA) studies and interrupted time-series studies. History Cochrane, previously known as the Cochrane Collaboration, was founded in 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MD Anderson
Monroe Dunaway Anderson (1873–1939) was a banker and cotton trader from Jackson, Tennessee. With William L. Clayton, Anderson built Anderson, Clayton and Company (formed in 1904 by his brother Frank E. Anderson and Frank's brother-in-law, William L. Clayton) into the world's biggest cotton company. In the event of one of their deaths, the partnership would lose a large amount of money to estate taxes and might be forced to dissolve. In order to avoid this, Anderson created the M.D. Anderson Foundation with an initial sum of $300,000. In 1939, after Anderson's death the foundation received an additional $19 million. In 1941, the Texas Legislature appropriated $500,000 to build a cancer hospital and research center. The M.D. Anderson Foundation agreed to match the state funds if the hospital were located in Houston at the Texas Medical Center (another project of the Anderson Foundation), and named after Anderson. Using surplus World War II Army barracks, the hospital operated fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institute For Occupational Safety And Health
The National Institute for Occupational Safety and Health (NIOSH, ) is the United States federal agency responsible for conducting research and making recommendations for the prevention of work-related injury and illness. NIOSH is part of the Centers for Disease Control and Prevention (CDC) within the U.S. Department of Health and Human Services. Despite its name, it is not part of the National Institutes of Health. Its current director is John Howard. NIOSH is headquartered in Washington, D.C., with research laboratories and offices in Cincinnati, Ohio; Morgantown, West Virginia; Pittsburgh, Pennsylvania; Denver, Colorado; Anchorage, Alaska; Spokane, Washington; and Atlanta, Georgia. NIOSH is a professionally diverse organization with a staff of 1,200 people representing a wide range of disciplines including epidemiology, medicine, industrial hygiene, safety, psychology, engineering, chemistry, and statistics. The Occupational Safety and Health Act, signed by President Rich ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hazardous Drugs
In pharmacology, hazardous drugs are drugs that are known to cause harm, which may or may not include ''genotoxicity'' (the ability to cause a change or mutation in genetic material). Genotoxicity might involve ''carcinogenicity'', the ability to cause cancer in animal models, humans or both; ''teratogenicity'', which is the ability to cause defects on fetal development or fetal malformation; and lastly hazardous drugs are known to have the potential to cause fertility impairment, which is a major concern for most clinicians.National Institute for Occupational Safety and Health (NIOSH). 2004. NIOSH Publication N. 2004-165 https://www.cdc.gov/niosh/docs/2004-165/ These drugs can be classified as '' antineoplastics'', cytotoxic agents, biologic agents, antiviral agents and immunosuppressive agents. This is why safe handling of hazardous drugs is crucial. Safe handling Safe handling refers to the process in which health care workers adhere to practices set forth by national health and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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