Clivus (anatomy)
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Clivus (anatomy)
The clivus (, Latin for "slope"), or Blumenbach clivus, is a bony part of the cranium The skull is a bone protective cavity for the brain. The skull is composed of four types of bone i.e., cranial bones, facial bones, ear ossicles and hyoid bone. However two parts are more prominent: the cranium and the mandible. In humans, the ... at the base of the skull. It is a shallow depression behind the dorsum sellae of the sphenoid bone. It slopes gradually to the anterior part of the basilar occipital bone at its junction with the sphenoid bone. It extends to the foramen magnum. It is related to the pons and the abducens nerve (CN VI). Structure The clivus is a shallow depression behind the dorsum sellae of the sphenoid bone. It slopes gradually to the anterior part of the basilar occipital bone at its junction with the sphenoid bone. Synchondrosis of these two bones forms the clivus. The clivus extends inferiorly to the foramen magnum. On axial planes, it sits just posterior to ...
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Latin Language
Latin (, or , ) is a classical language belonging to the Italic languages, Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the Roman Republic it became the dominant language in the Italy (geographical region), Italian region and subsequently throughout the Roman Empire. Even after the Fall of the Western Roman Empire, fall of Western Rome, Latin remained the common language of international communication, science, scholarship and academia in Europe until well into the 18th century, when other regional vernaculars (including its own descendants, the Romance languages) supplanted it in common academic and political usage, and it eventually became a dead language in the modern linguistic definition. Latin is a fusional language, highly inflected language, with three distinct grammatical gender, genders (masculine, feminine, and neuter), six or seven ...
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Fossa Navicularis Magna
Fossa navicularis magna (also known as ''pharyngeal fossa'' or ''phyaryngeal fovela'') is a variant bony depression found at the midline of the occipital part of clivus. This fossa was first described by Tourtual. Its prevalence ranges from 0.9 to 5.3%. Structure Fossa navicularis magna is located on the anterior surface or pharyngeal surface of the clivus. Its position when present is between the spheno-occipital synchondrosis and the foramen magnum. Size of this fossa varies considerably and its depth ranges from 3.49 to 4.94 mm. A histological study reported the presence of loose connective tissue containing collagen and elastic fibers within the fossa navicularis magna. Development Two theories have been proposed to explain the formation of fossa navicularis magna. It is believed that the fossa is formed as a remnant of the notochord or residue of the channels for emissary veins. Clinical significance Different pathologies were found associated with fossa navicularis ma ...
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Dens (anatomy)
In anatomy, the axis (from Latin ''axis'', "axle") or epistropheus is the second cervical vertebra (C2) of the spine, immediately inferior to the atlas, upon which the head rests. The axis' defining feature is its strong odontoid process (bony protrusion) known as the dens, which rises dorsally from the rest of the bone. Structure The body is deeper in front or in the back and is prolonged downward anteriorly to overlap the upper and front part of the third vertebra. It presents a median longitudinal ridge in front, separating two lateral depressions for the attachment of the longus colli muscles. Odontoid Process of Axis (Dens) The dens, also called the odontoid process or the peg, is the most pronounced projecting feature of the axis. The dens exhibits a slight constriction where it joins the main body of the vertebra. The condition where the dens is separated from the body of the axis is called ''os odontoideum'' and may cause nerve and circulation compression syndrome. ...
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Radiography
Radiography is an imaging technique using X-rays, gamma rays, or similar ionizing radiation and non-ionizing radiation to view the internal form of an object. Applications of radiography include medical radiography ("diagnostic" and "therapeutic") and industrial radiography. Similar techniques are used in airport security (where "body scanners" generally use backscatter X-ray). To create an image in conventional radiography, a beam of X-rays is produced by an X-ray generator and is projected toward the object. A certain amount of the X-rays or other radiation is absorbed by the object, dependent on the object's density and structural composition. The X-rays that pass through the object are captured behind the object by a detector (either photographic film or a digital detector). The generation of flat two dimensional images by this technique is called projectional radiography. In computed tomography (CT scanning) an X-ray source and its associated detectors rotate around the su ...
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Cervical Spine
In tetrapods, cervical vertebrae (singular: vertebra) are the vertebrae of the neck, immediately below the skull. Truncal vertebrae (divided into thoracic and lumbar vertebrae in mammals) lie caudal (toward the tail) of cervical vertebrae. In sauropsid species, the cervical vertebrae bear cervical ribs. In lizards and saurischian dinosaurs, the cervical ribs are large; in birds, they are small and completely fused to the vertebrae. The vertebral transverse processes of mammals are homologous to the cervical ribs of other amniotes. Most mammals have seven cervical vertebrae, with the only three known exceptions being the manatee with six, the two-toed sloth with five or six, and the three-toed sloth with nine. In humans, cervical vertebrae are the smallest of the true vertebrae and can be readily distinguished from those of the thoracic or lumbar regions by the presence of a foramen (hole) in each transverse process, through which the vertebral artery, vertebral veins, and inferio ...
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Endoscopic Endonasal Surgery
Endoscopic endonasal surgery is a minimally invasive technique used mainly in neurosurgery and otolaryngology. A neurosurgeon or an otolaryngologist, using an endoscope that is entered through the nose, fixes or removes brain defects or tumors in the anterior skull base. Normally an otolaryngologist performs the initial stage of surgery through the nasal cavity and sphenoid bone; a neurosurgeon performs the rest of the surgery involving drilling into any cavities containing a neural organ such as the pituitary gland. The use of endoscope was first introduced in Transsphenoidal Pituitary Surgery by R Jankowsky, J Auque, C Simon et al. in 1992 G (Laryngoscope. 1992 Feb;102(2):198-202). Introduction History of endoscopic endonasal surgery Antonin Jean Desomeaux, a urologist from Paris, was the first person to use the term, endoscope. However, the precursor to the modern endoscope was invented in the 1800s when a physician in Frankfurt, Germany by the name of Philipp Bozzini, develo ...
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ...
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Chordoma
Chordoma is a rare slow-growing neoplasm thought to arise from cellular remnants of the notochord. The evidence for this is the location of the tumors (along the neuraxis), the similar immunohistochemical staining patterns, and the demonstration that notochordal cells are preferentially left behind in the clivus and sacrococcygeal regions when the remainder of the notochord regresses during fetal life. In layman's terms, chordoma is a type of spinal cancer. Presentation Chordomas can arise from bone in the skull base and anywhere along the spine. The two most common locations are cranially at the clivus and in the sacrum at the bottom of the spine. Sacral chordoma is presented with chronic low back pain. Genetics A small number of families have been reported in which multiple relatives have been affected by chordoma. In four of these families, duplication of the brachyury gene was found to be responsible for causing chordoma. A possible association with tuberous sclerosi ...
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Palsy
Palsy is a medical term which refers to various types of paralysisDan Agin, ''More Than Genes: What Science Can Tell Us About Toxic Chemicals, Development, and the Risk to Our Children;; (2009), p. 172. or paresis, often accompanied by weakness and the loss of feeling and uncontrolled body movements such as shaking. The word originates from the Anglo-Norman ''paralisie'', ''parleisie'' ''et al.'', from the accusative form of Latin ''paralysis'', from Ancient Greek παράλυσις (''parálusis''), from παραλύειν (''paralúein'', “to disable on one side”), from παρά (''pará'', “beside”) + λύειν (''lúein'', “loosen”). The word is longstanding in the English language, having appeared in the play ''Grim the Collier of Croydon'', reported to have been written as early as 1599: In some editions, the Bible passage of Luke 5:18 is translated to refer to "a man which was taken with a palsy". More modern editions simply refer to a man who is paralysed. Al ...
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Intracranial Pressure
Intracranial pressure (ICP) is the pressure exerted by fluids such as cerebrospinal fluid (CSF) inside the skull and on the brain tissue. ICP is measured in millimeters of mercury (mmHg) and at rest, is normally 7–15 Millimeter of mercury, mmHg for a Supine position, supine adult. The body has various mechanisms by which it keeps the ICP stable, with CSF pressures varying by about 1 mmHg in normal adults through shifts in production and absorption of CSF. Changes in ICP are attributed to volume changes in one or more of the constituents contained in the cranium. CSF pressure has been shown to be influenced by abrupt changes in intrathoracic pressure during coughing (which is induced by contraction of the diaphragm and abdominal wall muscles, the latter of which also increases intra-abdominal pressure), the valsalva maneuver, and communication with the vasculature (venous and arterial systems). Intracranial hypertension (IH), also called increased ICP (IICP) or raised intracrani ...
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Saunders (imprint)
Saunders is an American academic publisher based in the United States. It is currently an imprint of Elsevier. Formerly independent, the W. B. Saunders company was acquired by CBS in 1968, who added it to their publishing division Holt, Rinehart & Winston. When CBS left the publishing field in 1986, it sold the academic publishing units to Harcourt Brace Jovanovich. Harcourt was acquired by Reed Elsevier in 2001."Reed Elsevier Timeline"
. . Retrieved May 2, 2015. W. B. Saunders published the Kinsey Reports and