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Classical Swine Fever
Classical swine fever (CSF) or hog cholera (also sometimes called pig plague based on the German word ) is a highly contagious disease of swine (Old World and New World pigs). It has been mentioned as a potential bioweapon. Clinical signs Swine fever causes fever, skin lesions, convulsions, splenic infarctions and usually (particularly in young animals) death within 15 days. The disease has acute and chronic forms, and can range from severe, with high mortality, to mild or even unapparent. In the acute form of the disease, in all age groups, there is fever, huddling of sick animals, loss of appetite, dullness, weakness, conjunctivitis, constipation followed by diarrhoea, and an unsteady gait. Several days after the onset of clinical signs, the ears, abdomen and inner thighs may show a purple discoloration. Animals with acute disease die within 1–2 weeks. Severe cases of the disease appear very similar to African swine fever. With low-virulence strains, the only expression ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swine Influenza
Swine influenza is an infection caused by any of several types of swine influenza viruses. Swine influenza virus (SIV) or swine-origin influenza virus (S-OIV) refers to any strain of the influenza family of viruses that is endemic in pigs. As of 2009, identified SIV strains include influenza C and the subtypes of influenza A known as H1N1, H1N2, H2N1, H3N1, H3N2, and H2N3. Swine influenza virus is common throughout pig populations worldwide. Transmission of the virus from pigs to humans is rare, and does not always lead to human flu, often resulting only in the production of antibodies in the blood. If transmission causes human flu, it is called zoonotic swine flu. People with regular exposure to pigs are at increased risk of swine flu infections. Around the mid-20th century, identification of influenza subtypes was made possible, allowing accurate diagnosis of transmission to humans. Since then, only 50 such transmissions have been confirmed. These strains of swine flu rarel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Forensic DNA Analysis
DNA profiling is the determination of a DNA profile for legal and investigative purposes. DNA analysis methods have changed numerous times over the years as technology improves and allows for more information to be determined with less starting material. Modern DNA analysis is based on the statistical calculation of the rarity of the produced profile within a population. While most well known as a tool in forensic investigations, DNA profiling can also be used for non-forensic purposes such as paternity testing and human genealogy research. History The methods for producing a DNA profile were developed by Alec Jeffreys and his team in 1984. Methods Retired methods RFLP analysis The first true method of DNA profiling was restriction fragment length polymorphism analysis. The first use of RFLP analysis in forensic casework was in 1985 in the United Kingdom. This type of analysis used variable number tandem repeats (VNTRs) to distinguish between individuals. VNTRs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research In Veterinary Science
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MDPI
MDPI (Multidisciplinary Digital Publishing Institute) is a publisher of open access scientific journals. Founded by Shu-Kun Lin as a chemical sample archive, it now publishes over 390 peer-reviewed, open access journals. MDPI is the largest open access publisher in the world and the fifth largest publisher overall in terms of journal paper output. The number of published papers has been growing significantly in the last decade with year over year growth of over 50% in 2017, 2018 and 2019. As of June 2022, MDPI publishes 393 academic journals, including 93 journals indexed within the Science Citation Index Expanded, and 8 journals indexed within the Social Sciences Citation Index, with a total of 98 journals ranked with an impact factor. MDPI journals are included in the Directory of Open Access Journals. MDPI is a member of the Open Access Scholarly Publishers Association, a participating publisher and supporter of the Initiative for Open Citations, and a member of the Committ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viruses (journal)
''Viruses'' is a monthly peer-reviewed open access scientific journal published by MDPI covering all aspects of virology. It was established in 2009. The editor-in-chief is Eric O. Freed (National Cancer Institute). The journal is associated with the American Society for Virology, Australasian Virology Society, Brazilian Society for Virology, Canadian Society for Virology, German Society for Virology, Italian Society for Virology, Spanish Society for Virology, and Swedish Society for Virology. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 5.818, ranking it 10th out of 36 journals in the category "Virology". It has a Sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ATCvet
The Anatomical Therapeutic Chemical (ATC) Classification System is a drug classification system that classifies the active ingredients of drugs according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties. Its purpose is an aid to monitor drug use and for research to improve quality medication use. It does not imply drug recommendation or efficacy. It is controlled by the World Health Organization Collaborating Centre for Drug Statistics Methodology (WHOCC), and was first published in 1976. Coding system This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act, their therapeutic intent or nature, and the drug's chemical characteristics. Different brands share the same code if they have the same active substance and indications. Each bottom-level ATC code stands for a pharmaceutically used substance, or a combination of substances, in a single indication (or us ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemorrage
Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, vagina or anus, or through a puncture in the skin. Hypovolemia is a massive decrease in blood volume, and death by excessive loss of blood is referred to as exsanguination. Typically, a healthy person can endure a loss of 10–15% of the total blood volume without serious medical difficulties (by comparison, blood donation typically takes 8–10% of the donor's blood volume). The stopping or controlling of bleeding is called hemostasis and is an important part of both first aid and surgery. Types * Upper head ** Intracranial hemorrhage – bleeding in the skull. ** Cerebral hemorrhage – a type of intracranial hemorrhage, bleeding within the brain tissue itself. ** Intracerebral hemorrhage – bleeding in the brain caused by the rupture of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurological
Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic or translational research. While neurology is a nonsurgical specialty, its corresponding surgical specialty is neurosurgery. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iowa State University
Iowa State University of Science and Technology (Iowa State University, Iowa State, or ISU) is a public land-grant research university in Ames, Iowa. Founded in 1858 as the Iowa Agricultural College and Model Farm, Iowa State became one of the nation's first designated land-grant institution when the Iowa Legislature accepted the provisions of the 1862 Morrill Act on September 11, 1862, making Iowa the first state in the nation to do so. On July 4, 1959, the college was officially renamed Iowa State University of Science and Technology. Iowa State is classified among "R1: Doctoral Universities – Very high research activity". The university is home to the Ames Laboratory, one of ten national U.S. Department of Energy Office of Science research laboratories, the Biorenewables Research Laboratory, the Plant Sciences Institute, and various other research institutes. Iowa State is the second-largest university in the State of Iowa by undergraduate enrollment. The university's ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flaviviridae
''Flaviviridae'' is a family of enveloped positive-strand RNA viruses which mainly infect mammals and birds. They are primarily spread through arthropod vectors (mainly ticks and mosquitoes). The family gets its name from the yellow fever virus; ''flavus'' is Latin for "yellow", and yellow fever in turn was named because of its propensity to cause jaundice in victims. There are 89 species in the family divided among four genera. Diseases associated with the group include: hepatitis (hepaciviruses), hemorrhagic syndromes, fatal mucosal disease (pestiviruses), hemorrhagic fever, encephalitis, and the birth defect microcephaly (flaviviruses). Structure Virus particles are enveloped and spherical with icosahedral-like geometries that have pseudo T=3 symmetry. They are about 40–60 nm in diameter. Genome Members of the family ''Flaviviridae'' have monopartite, linear, single-stranded RNA genomes of positive polarity, and 9.6 to 12.3 kilobase in total length. The 5'-termini of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pestivirus
''Pestivirus'' is a genus of viruses, in the family ''Flaviviridae''. Viruses in the genus ''Pestivirus'' infect mammals, including members of the family Bovidae (which includes cattle, sheep, and goats) and the family Suidae (which includes various species of swine). There are 11 species in this genus. Diseases associated with this genus include: hemorrhagic syndromes, abortion, and fatal mucosal disease. Structure Viruses in ''Pestivirus'' are enveloped, with spherical geometries. Their diameter is around 50 nm. Genomes are linear and not segmented, around 12kb in length. Lifecycle Entry into the host cell is achieved by attachment of the viral envelope protein E2 to host receptors, which mediates clathrin-mediated endocytosis. The main viral replication process happens in host cytoplasm. Replication follows the Positive-strand RNA virus, positive strand RNA virus replication model. An Internal ribosome entry site, IRES RNA element at the 5'-nontranslated region (NTR) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
