Chronic Superficial Keratitis
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Chronic Superficial Keratitis
Chronic superficial keratitis (CSK), also known as pannus or Uberreiter's disease, is an inflammatory condition of the cornea in dogs, particularly seen in the German Shepherd. Both eyes are usually affected. The corneas gradually become pigmented and infiltrated by blood vessels, and the dog may eventually become blind. Signs and symptoms CSK is usually a bilateral progressive condition, however the lesions are not symmetrical nor are they painful. Signs include pigmentation and vascularization of the cornea (extension of blood vessels onto the cornea). It is usually first seen at the lateral (temporal) limbus (the junction between the cornea and sclera), although it eventually can extend from any part of the limbus to cover the entire cornea. Severe cases can cause blindness. Although CSK is usually identifiable by the appearance of the eye and the breed of the affected dog, cytology will reveal the presence of lymphocytes and plasma cells. Cause CSK is immune-mediated in ...
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Canine Pannus
Canine may refer to: Zoology and anatomy * a dog-like Canid animal in the subfamily Caninae ** '' Canis'', a genus including dogs, wolves, coyotes, and jackals ** Dog, the domestic dog * Canine tooth, in mammalian oral anatomy People with the surname * Henry Canine (), American football coach * Ralph Canine (1895–1969), founding director of the United States National Security Agency Other uses * Canine, a fictional dog in the '' Glenn Martin, DDS'' animated television series * Canine Hills, Antarctic landform in the Bowers Mountains, Victoria Land See also * K9 (other) * Kanine (other) * Canina (other) * Cani (other) * List of canids Canidae is a family of mammals in the order Carnivora, which includes domestic dogs, wolves, coyotes, foxes, jackals, dingoes, and many other extant and extinct dog-like mammals. A member of this family is called a canid; all extant species are a ...
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Pimecrolimus
Pimecrolimus is an immunomodulating agent of the calcineurin inhibitor class used in the treatment of atopic dermatitis (eczema). It is available as a topical cream, once marketed by Novartis (however, Galderma has been promoting the compound in Canada since early 2007) under the trade name Elidel. Medical uses It has been proven to be effective in various inflammatory skin diseases, e.g., seborrheic dermatitis, cutaneous lupus erythematosus, oral lichen planus, vitiligo, and psoriasis. Tacrolimus and pimecrolimus are both calcineurin inhibitors and function as immunosuppressants. Side effects In January 2006, the United States Food and Drug Administration (FDA) announced that Elidel packaging would be required to carry a black box warning regarding the potential increased risk of lymph node or skin cancer, as for the similar drug tacrolimus, whereas current practice by UK dermatologists is not to consider this a significant real concern and they are increasingly recommend ...
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Uveal Cyst
Iris cysts are hollow cavities in the eye filled with secretion. They come in various sizes, numbers, shapes, pigments and can be free-floating, attached to the pupillary margin or within the posterior chamber. Most frequently iris cysts don't cause any issues, but they can cause problems like: " fly biting" behavior, corneal endothelial pigment, lens capsular pigmentation, altered iris movement, decreased aqueous outflow with subsequent glaucoma or block the vision when grown too big. They can be acquired or innate. Possible causes are inflammation, drug-induced, uveitis, a trauma, tumor-induced, parasitic or implantation. Most frequently iris cysts are benign and need no treatment. Sometimes iris cysts are causing problems and need to be deflated. Iris cysts can be treated with trans corneal diode laser treatment, fine-needle aspiration or surgical excision. For the treatment of iris cysts is a conservative approach favored. Introduction Mackenzie diagnosed the first iris cys ...
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Border Collie
The Border Collie is a Scottish breed of herding dog of medium size. Widely considered to be the most intelligent dog breed, they are descended from landrace sheepdogs once found all over the British Isles, but became standardised in the Anglo-Scottish border region. They are now mostly used as working dogs to herd livestock, specifically sheep. Border Collies are extremely energetic, acrobatic, and athletic. They frequently compete with great success in sheepdog trials and a range of dog sports like dog obedience, disc dog, herding and dog agility. Border Collies continue to be employed in their traditional work of herding livestock throughout the world and are kept as pets. Description In general, Border Collies are medium-sized dogs with a moderate amount of coat, which is more often thick and prone to shedding. They have a double coat that varies from smooth to rough and is occasionally curled. While black and white is the most commonly seen colour pattern of the Bor ...
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Australian Shepherd
The Australian Shepherd is a breed of herding dog from the United States. The name of the breed is technically a misnomer, as it was developed in California in the 19th century; the breed was unknown in Australia at the time. It is claimed that Australian Shepherds descend from a variety of herding breeds, including collies imported, alongside sheep, from Australia and New Zealand; the breed reportedly took its name from this trade. Originally used solely as a herding dog, the Australian Shepherd has become one of the most popular companion dog breeds in North America. History The Australian Shepherd descends in part from pastoral dogs brought to herd Spanish flocks in North America as early as the 1500s. There is some speculation that these dogs included the Carea Leonés, a mountain sheepdog that can display the eye color and merle coat found in many contemporary Australian Shepherds. It is sometimes claimed that the Basque Shepherd Dog and the Pyrenean Sheepdog were also amon ...
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Greyhound
The English Greyhound, or simply the Greyhound, is a breed of dog, a sighthound which has been bred for coursing, greyhound racing and hunting. Since the rise in large-scale adoption of retired racing Greyhounds, the breed has seen a resurgence in popularity as a family pet. Greyhounds are defined as a tall, muscular, smooth-coated, "S-shaped" type of sighthound with a long tail and tough feet. Greyhounds are a separate breed from other related sighthounds, such as the Italian greyhound. The Greyhound is a gentle and intelligent breed whose combination of long, powerful legs, deep chest, flexible spine, and slim build allows it to reach average race speeds exceeding . The Greyhound can reach a full speed of within , or six strides from the boxes, traveling at almost for the first of a race. Appearance Males are usually tall at the withers, and weigh on average . Females tend to be smaller, with shoulder heights ranging from and weights from , although weights ca ...
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Belgian Tervuren
The Belgian Shepherd (also known as the Belgian Sheepdog, Belgian Malinois, or the Chien de Berger Belge) is a Dog breed, breed of medium-sized herding dog from Belgium. While predominantly considered a single breed, it is bred in four distinct varieties based on coat type and colour; the long-haired black Groenendael, the rough-haired fawn Laekenois, the short-haired fawn Malinois, and the long-haired fawn Tervuren; in the United States the American Kennel Club considers the four varieties to be separate breeds. The breed descends from a common type of shepherd dog found throughout Western Europe that includes such modern breeds as the Bouvier des Ardennes, Dutch Shepherd and German Shepherd. A common sight in the service of Belgian shepherds for centuries, it was not until the end of the 19th century that a breed club was formed and attempts were made to standardise the breed. In addition to its historical role as a herding dog, Belgian Shepherds have been used as assistan ...
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Sunglasses
Sunglasses or sun glasses (informally called shades or sunnies; more names below) are a form of protective eyewear designed primarily to prevent bright sunlight and high-energy visible light from damaging or discomforting the eyes. They can sometimes also function as a visual aid, as variously termed spectacles or glasses exist, featuring lenses that are colored, polarized or darkened. In the early 20th century, they were also known as sun cheaters (cheaters then being an American slang term for glasses). Since the 1930s, sunglasses have been a popular fashion accessory, especially on the beach. The American Optometric Association recommends wearing sunglasses that block ultraviolet radiation (UV) whenever a person is in the sunlight to protect the eyes from UV and blue light, which can cause several serious eye problems. Their usage is mandatory immediately after some surgical procedures, such as LASIK, and recommended for a certain time period in dusty areas, when leaving ...
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Radiation Therapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. Ionizing radiation works by damaging the DNA of cancerous tissue ...
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Strontium-90
Strontium-90 () is a radioactive isotope of strontium produced by nuclear fission, with a half-life of 28.8 years. It undergoes β− decay into yttrium-90, with a decay energy of 0.546 MeV. Strontium-90 has applications in medicine and industry and is an isotope of concern in fallout from nuclear weapons, nuclear weapons testing, and nuclear accidents. Radioactivity Naturally occurring strontium is nonradioactive and nontoxic at levels normally found in the environment, but 90Sr is a radiation hazard. 90Sr undergoes β− decay with a half-life of 28.79 years and a decay energy of 0.546 MeV distributed to an electron, an antineutrino, and the yttrium isotope 90Y, which in turn undergoes β− decay with a half-life of 64 hours and a decay energy of 2.28 MeV distributed to an electron, an antineutrino, and 90Zr (zirconium), which is stable. Note that 90Sr/Y is almost a pure beta particle source; the gamma photon emission from the decay of 90Y is so infrequent that it ...
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Cytokines are peptides and cannot cross the lipid bilayer of cells to enter the cytoplasm. Cytokines have been shown to be involved in autocrine, paracrine and endocrine signaling as immunomodulating agents. Cytokines include chemokines, interferons, interleukins, lymphokines, and tumour necrosis factors, but generally not hormones or growth factors (despite some overlap in the terminology). Cytokines are produced by a broad range of cells, including immune cells like macrophages, B lymphocytes, T lymphocytes and mast cells, as well as endothelial cells, fibroblasts, and various stromal cells; a given cytokine may be produced by more than one type of cell. They act through cell surface receptors and are especially important in the immune system; cytokines modulate the balance between humoral and cell-based immune responses, and they regulate the maturation, growth, and res ...
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