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Christophe Fraser
Christophe Fraser is a professor of Infectious Disease Epidemiology in the Big Data Institute, part of the Nuffield Department of Medicine at the University of Oxford. Fraser's PhD and initial postdoctoral research were in theoretical particle physics. He converted to infectious disease epidemiology in 1998, based first at the University of Oxford then at Imperial College London, where he became Chair of Theoretical Epidemiology and served as deputy director of the MRC Centre for Outbreak Analysis and Modelling under director Neil Ferguson (epidemiologist). He returned to the University of Oxford in 2016 as Senior Group Leader in Pathogen Dynamics at the Big Data Institute. In 2022 he was appointed Moh Family Foundation Professor of Infectious Disease Epidemiology as part of the University of Oxford's newly created Pandemic Sciences Institute. Research on HIV Fraser and colleagues were among the first to hypothesise that the large variability in virulence observed b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heritability
Heritability is a statistic used in the fields of breeding and genetics that estimates the degree of ''variation'' in a phenotypic trait in a population that is due to genetic variation between individuals in that population. The concept of heritability can be expressed in the form of the following question: "What is the proportion of the variation in a given trait within a population that is ''not'' explained by the environment or random chance?" Other causes of measured variation in a trait are characterized as environmental factors, including observational error. In human studies of heritability these are often apportioned into factors from "shared environment" and "non-shared environment" based on whether they tend to result in persons brought up in the same household being more or less similar to persons who were not. Heritability is estimated by comparing individual phenotypic variation among related individuals in a population, by examining the association between ind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2012 MERS Outbreak
Middle East respiratory syndrome outbreak (MERS outbreak) may refer to: * 2012 Middle East respiratory syndrome outbreak (2012 MERS outbreak) * 2015 Middle East respiratory syndrome outbreak in South Korea (2015 MERS outbreak) * 2018 Middle East respiratory syndrome outbreak (2018 MERS outbreak) See also *MERS Middle East respiratory syndrome (MERS) is a viral respiratory infection caused by ''Middle East respiratory syndrome–related coronavirus'' (MERS-CoV). Symptoms may range from none, to mild, to severe. Typical symptoms include fever, cough, ..., Middle East respiratory syndrome, a disease ** Middle East respiratory syndrome–related coronavirus, the virus that causes the disease * Severe acute respiratory syndrome outbreak (other) {{disambiguation Outbreaks 2012 disease outbreaks 2015 disease outbreaks 2018 disease outbreaks ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2009 Swine Flu Pandemic
The 2009 swine flu pandemic, caused by the H1N1 influenza virus and declared by the World Health Organization (WHO) from June 2009 to August 2010, is the third recent flu pandemic involving the H1N1 virus (the first being the 1918–1920 Spanish flu pandemic and the second being the 1977 Russian flu). The first two cases were discovered independently in the United States in April 2009. The virus appeared to be a new strain of H1N1 that resulted from a previous triple reassortment of bird, swine, and human flu viruses which further combined with a Eurasian pig flu virus, leading to the term "swine flu". Some studies estimated that the real number of cases including asymptomatic and mild cases could be 700 million to 1.4 billion people—or 11 to 21 percent of the global population of 6.8 billion at the time. The lower value of 700 million is more than the 500 million people estimated to have been infected by the Spanish flu pandemic. However, the Spanish flu infected approxima ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2002–2004 SARS Outbreak
The 2002–2004 outbreak of SARS, caused by severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), infected over 8,000 people from 29 countries and territories, and resulted in at least 774 deaths worldwide. The outbreak was first identified in Foshan, Guangdong, China, in November 2002. The World Health Organization (WHO) was notified of the outbreak in February 2003, and issued a global alert in March 2003. Initially, the cause of the outbreak was unknown, and some media outlets reported that an influenza virus was a potential culprit. The major part of the outbreak lasted about 8 months, and the World Health Organization declared SARS contained on 5 July 2003. However, several SARS cases were reported until May 2004. In late December 2019, SARS-CoV-2, a new strain of coronavirus closely related to the one that caused SARS, was discovered in Wuhan, Hubei, China. The new strain causes COVID-19, a disease which has since spread worldwide, leading to an ongo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Outbreaks
In epidemiology, an outbreak is a sudden increase in occurrences of a disease when cases are in excess of normal expectancy for the location or season. It may affect a small and localized group or impact upon thousands of people across an entire continent. The number of cases varies according to the disease-causing agent, and the size and type of previous and existing exposure to the agent. Outbreaks include many epidemics, which term is normally only for infectious diseases, as well as diseases with an environmental origin, such as a water or foodborne disease. They may affect a region in a country or a group of countries. Pandemics are near-global disease outbreaks when multiple and various countries around the Earth are soon infected. Definition The terms "outbreak" and "epidemic" have often been used interchangeably. Researchers Manfred S. Green and colleagues propose that the latter term be restricted to larger events, pointing out that '' Chambers Concise Dictionary'' and ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agent-based Model
An agent-based model (ABM) is a computational model for simulating the actions and interactions of autonomous agents (both individual or collective entities such as organizations or groups) in order to understand the behavior of a system and what governs its outcomes. It combines elements of game theory, complex systems, emergence, computational sociology, multi-agent systems, and evolutionary programming. Monte Carlo methods are used to understand the stochasticity of these models. Particularly within ecology, ABMs are also called individual-based models (IBMs). A review of recent literature on individual-based models, agent-based models, and multiagent systems shows that ABMs are used in many scientific domains including biology, ecology and social science. Agent-based modeling is related to, but distinct from, the concept of multi-agent systems or multi-agent simulation in that the goal of ABM is to search for explanatory insight into the collective behavior of agents obeying ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthony Finkelstein
Sir Anthony Charles Wiener Finkelstein (born 28 July 1959 ) is a British engineer and computer scientist. He is the President of City, University of London. He was Chief Scientific Adviser for National Security to HM Government until 2021. Education and early life Anthony Finkelstein was born on 28 July 1959. He was educated at University College School, the University of Bradford (BEng), the London School of Economics (MSc) and the Royal College of Art (PhD, 1985). Career and research Finkelstein's scientific work is in the broad area of software development tools and processes. He has also worked on applications of systems modelling in the life sciences. He was appointed President of City, University of London in June 2021. He is a member of Council of UK Research and Innovation (UKRI) and Chair of the Police Science Council established by the National Police Chiefs' Council (NPCC). He was Chief Scientific Adviser for National Security to HM Government from 2015 until 20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a provisional name, 2019 novel coronavirus (2019-nCoV), and has also been called the human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization declared the outbreak a public health emergency of international concern on January 30, 2020, and a pandemic on March 11, 2020. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is contagious in humans. SARS‑CoV‑2 is a virus of the species ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV), related to the SARS-CoV-1 virus that caused the 2002–2004 SARS outbreak. Despite its close relation to SARS-CoV-1, its closest known relatives, with which it forms a sister group, are the derived SARS ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Apps
COVID-19 apps include mobile-software applications for digital contact-tracing - i.e. the process of identifying persons ("contacts") who may have been in contact with an infected individual - deployed during the COVID-19 pandemic. Numerous tracing applications have been developed or proposed, with official government support in some territories and jurisdictions. Several frameworks for building contact-tracing apps have been developed. Privacy concerns have been raised, especially about systems that are based on tracking the geographical location of app users. Less overtly intrusive alternatives include the co-option of Bluetooth signals to log a user's proximity to other cellphones. (Bluetooth technology has form in tracking cell-phones' locations.) On 10 April 2020, Google and Apple jointly announced that they would integrate functionality to support such Bluetooth-based apps directly into their Android and iOS operating systems. India's COVID-19 tracking app ''Aarogya Se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic
The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identified in an outbreak in the Chinese city of Wuhan in December 2019. Attempts to contain it there failed, allowing the virus to spread to other areas of Asia and later worldwide. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern on 30 January 2020, and a pandemic on 11 March 2020. As of , the pandemic had caused more than cases and confirmed deaths, making it one of the deadliest in history. COVID-19 symptoms range from undetectable to deadly, but most commonly include fever, dry cough, and fatigue. Severe illness is more likely in elderly patients and those with certain underlying medical conditions. COVID-19 transmits when people breathe in air contaminated by droplets and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UNAIDS
The Joint United Nations Programme on HIV and AIDS (UNAIDS) (, ONUSIDA) is the main advocate for accelerated, comprehensive and coordinated global action on the HIV/AIDS pandemic. The mission of UNAIDS is to lead, strengthen and support an expanded response to HIV and AIDS that includes preventing transmission of HIV, providing care and support to those already living with the virus, reducing the vulnerability of individuals and communities to HIV and alleviating the impact of the epidemic. UNAIDS seeks to prevent the HIV/AIDS epidemic from becoming a severe pandemic. UNAIDS is headquartered in Geneva, Switzerland, where it shares some site facilities with the World Health Organization. It is a member of the United Nations Development Group. Currently, Winnie Byanyima leads UNAIDS as executive director. Former executive directors are Peter Piot (1995–2008) and Michel Sidibé (2009–2019). The agency promotes the GIPA principle (greater involvement of people living with HI ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
