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Christiane Nüsslein-Volhard
Christiane (Janni) Nüsslein-Volhard (; born 20 October 1942) is a German developmental biologist and a 1995 Nobel Prize in Physiology or Medicine laureate. She is the only woman from Germany to have received a Nobel Prize in the sciences. Nüsslein-Volhard earned her PhD in 1974 from the University of Tübingen, where she studied protein-DNA interaction. She won the Albert Lasker Award for Basic Medical Research in 1991 and the Nobel Prize in Physiology or Medicine in 1995, together with Eric Wieschaus and Edward B. Lewis, for their research on the genetic control of embryonic development. Early life and education Nüsslein-Volhard was born in Magdeburg on 20 October 1942, the second of five children to Rolf Volhard, an architect, and Brigitte Haas Volhard, a nursery school teacher. She has four siblings: three sisters and one brother. She grew up and went to school in south Frankfurt, exposed to art and music and thus was "trained in looking at things and recognizing thing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magdeburg
Magdeburg (; nds, label=Low Saxon, Meideborg ) is the capital and second-largest city of the German state Saxony-Anhalt. The city is situated at the Elbe river. Otto I, the first Holy Roman Emperor and founder of the Archdiocese of Magdeburg, was buried in the city's cathedral after his death. Magdeburg's version of German town law, known as Magdeburg rights, spread throughout Central and Eastern Europe. In the Late Middle Ages, Magdeburg was one of the largest and most prosperous German cities and a notable member of the Hanseatic League. One of the most notable people from the city is Otto von Guericke, famous for his experiments with the Magdeburg hemispheres. Magdeburg has been destroyed twice in its history. The Catholic League sacked Magdeburg in 1631, resulting in the death of 25,000 non-combatants, the largest loss of the Thirty Years' War. During the World War II the Allies bombed the city in 1945 and destroying much of it. After World War II the city belonged t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Biologist
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryonic development of animals are: tissue patterning (via regional specification and patterned cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing to a specific region or part of the organism. These are defined ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Franz Volhard
Franz Volhard (2 May 1872 – 24 May 1950) was a German internist born in Munich. Academic career He studied medicine at the universities of Bonn, Strasbourg, and Halle. As a student his instructors included Eduard Friedrich Wilhelm Pflüger (1829–1910), Bernhard Naunyn (1839–1925), Oswald Schmiedeberg (1838–1921), and Joseph von Mering (1849–1908). From 1897 to 1905 he worked at the university medical clinic at Giessen under Franz Riegel (1843–1904). In 1905 he became head of the medical department at the city hospital in Dortmund, and in 1908 was named director of the ''Krankenanstalt'' in Mannheim, now University Hospital Mannheim. Afterwards, he served as a professor at the universities of Halle (from 1918) and Frankfurt (from 1927). Medical research Volhard made several important contributions in the fields of cardiology and nephrology. He is especially remembered for his collaborative work with pathologist Karl Theodor Fahr (1877–1945) in Mannheim, where th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jacob Volhard
Jacob Volhard (4 June 1834 – 14 January 1910) was the German chemist who discovered, together with his student Hugo Erdmann, the Volhard–Erdmann cyclization reaction. He was also responsible for the improvement of the Hell–Volhard–Zelinsky halogenation. From 1852 to 1855 he studied chemistry at the University of Giessen, and afterwards, furthered his education at the University of Heidelberg. For two years he worked as an assistant under Justus von Liebig at the University of Munich, and in 1860/61 studied with August Wilhelm von Hofmann in London. In 1863 he obtained his habilitation at Munich, where he subsequently became an associate professor. In the meantime, he worked in the Institute of Plant Physiology at the Bavarian Academy of Sciences (1865–76). In 1879 he was named a professor of organic chemistry at the University of Erlangen, then in 1882 relocated to the University of Halle, where he served as a professor up until 1908. Selected works * ''Die Begrün ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frankfurt
Frankfurt, officially Frankfurt am Main (; Hessian: , "Frank ford on the Main"), is the most populous city in the German state of Hesse. Its 791,000 inhabitants as of 2022 make it the fifth-most populous city in Germany. Located on its namesake Main River, it forms a continuous conurbation with the neighboring city of Offenbach am Main and its urban area has a population of over 2.3 million. The city is the heart of the larger Rhine-Main metropolitan region, which has a population of more than 5.6 million and is Germany's second-largest metropolitan region after the Rhine-Ruhr region. Frankfurt's central business district, the Bankenviertel, lies about northwest of the geographic center of the EU at Gadheim, Lower Franconia. Like France and Franconia, the city is named after the Franks. Frankfurt is the largest city in the Rhine Franconian dialect area. Frankfurt was a city state, the Free City of Frankfurt, for nearly five centuries, and was one of the most import ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of Regeneration (biology), regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryogenesis, embryonic development of animals are: tissue patterning (via regional specification and patterned cellular differentiation, cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embryo
An embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres are arranged as a solid ball that when reaching a certain size, called a morula, takes in fluid to create a cavity called a blastocoel. The structure is then termed a blastula, or a blastocyst in mammals. The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. Gastrulation is the formation of the three germ layers that will form all of the different parts of the body. Neurulation forms the nervous ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward B
Edward is an English given name. It is derived from the Anglo-Saxon name ''Ēadweard'', composed of the elements '' ēad'' "wealth, fortune; prosperous" and '' weard'' "guardian, protector”. History The name Edward was very popular in Anglo-Saxon England, but the rule of the Norman and Plantagenet dynasties had effectively ended its use amongst the upper classes. The popularity of the name was revived when Henry III named his firstborn son, the future Edward I, as part of his efforts to promote a cult around Edward the Confessor, for whom Henry had a deep admiration. Variant forms The name has been adopted in the Iberian peninsula since the 15th century, due to Edward, King of Portugal, whose mother was English. The Spanish/Portuguese forms of the name are Eduardo and Duarte. Other variant forms include French Édouard, Italian Edoardo and Odoardo, German, Dutch, Czech and Romanian Eduard and Scandinavian Edvard. Short forms include Ed, Eddy, Eddie, Ted, Teddy and Ned ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eric F
The given name Eric, Erich, Erikk, Erik, Erick, or Eirik is derived from the Old Norse name ''Eiríkr'' (or ''Eríkr'' in Old East Norse due to monophthongization). The first element, ''ei-'' may be derived from the older Proto-Norse ''* aina(z)'', meaning "one, alone, unique", ''as in the form'' ''Æ∆inrikr'' explicitly, but it could also be from ''* aiwa(z)'' "everlasting, eternity", as in the Gothic form ''Euric''. The second element ''- ríkr'' stems either from Proto-Germanic ''* ríks'' "king, ruler" (cf. Gothic ''reiks'') or the therefrom derived ''* ríkijaz'' "kingly, powerful, rich, prince"; from the common Proto-Indo-European root * h₃rḗǵs. The name is thus usually taken to mean "sole ruler, autocrat" or "eternal ruler, ever powerful". ''Eric'' used in the sense of a proper noun meaning "one ruler" may be the origin of ''Eriksgata'', and if so it would have meant "one ruler's journey". The tour was the medieval Swedish king's journey, when newly elected, to s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein-DNA Interaction
DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. Sequence-specific DNA-binding proteins generally interact with the major groove of B-DNA, because it exposes more functional groups that identify a base pair. However, there are some known minor groove DNA-binding ligands such as netropsin, distamycin, Hoechst 33258, pentamidine, DAPI and others. Examples DNA-binding proteins include transcription factors which modulate the process of transcription, various polymerases, nucleases which cleave DNA molecules, and histones which are involved in chromosome packaging and transcription in the cell nucleus. DNA-binding proteins can incorporate such domains as the zinc finger, the helix-turn-helix, and the leucine zipper (among many others) that facilitate binding to nucleic acid. There are also more unusual examples such as transcription activator like effectors. Non-specific DNA-protein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize In Literature
) , image = Nobel Prize.png , caption = , awarded_for = Outstanding contributions in literature , presenter = Swedish Academy , holder = Annie Ernaux (2022) , location = Stockholm, Sweden , year = 1901 , reward = 10 million SEK (2022) , website = , year2 = 2022 , holder_label = Currently held by , previous = 2021 , main = 2022 , next = 2023 The Nobel Prize in Literature (here meaning ''for'' literature) is a Swedish literature prize that is awarded annually, since 1901, to an author from any country who has, in the words of the will of Swedish industrialist Alfred Nobel, "in the field of literature, produced the most outstanding work in an idealistic direction" (original Swedish: ''den som inom litteraturen har producerat det utmärktaste i idealisk rigtning''). Though individual works are sometimes cited as being particularly noteworthy, the award is based on an author's body of work as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
