Christian Sell
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Christian Sell
Christian Sell is an American scientist who works as an associate professor in the department of biochemistry and molecular biology at the Drexel University College of Medicine. Education and career Sell attended the State University of New York at Binghampton, and received his bachelor's degree in biology in 1982. He then moved to Albany Medical College, where he received his PhD in pathology in 1990. He then continued his research career as a postdoctoral researcher, first at Temple University and then at Thomas Jefferson University. Finally, he joined the Medical College of Pennsylvania as an assistant professor in 1994. He moved to the Lankenau Institute for Medical Research as an associate investigator in 1998, and since 2005 has been a tenured associate professor at the Drexel University College of Medicine. From 2017 to 2018 Sell served as president of the American Aging Association, the largest scientific society devoted to the study of the biology of aging in the United ...
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Drexel University College Of Medicine
Drexel University College of Medicine is the medical school of Drexel University, a private research university in Philadelphia, Pennsylvania. The medical school represents the consolidation of two medical schools: the first U.S. medical school for women and the nation's first college of homeopathy. With one of the nation's largest enrollments for a private medical school, Drexel University College of Medicine is the second most applied-to medical school in the United States. It is ranked no. 83 in research by '' U.S. News & World Report''. The college is housed in East Falls, Philadelphia, Pennsylvania, at the Queen Lane Campus, near the Henry Ave site of the former Woman's Medical College of Pennsylvania. The Queen Lane Campus is primarily used by students during their preclinical training. The Center City Hahnemann University Hospital Campus was the college's primary teaching hospital until its closure in 2019. The College of Medicine follows a systems-based curriculum that ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Fellows Of The Gerontological Society Of America
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places * Fellows, California, USA * Fellows, Wisconsin, ghost town, USA Other uses * Fellows Auctioneers, established in 1876. *Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton * Fellows (surname) See also *North Fellows Historic District, listed on the National Register of Historic Places in Wapello County, Iowa *Justice Fellows (other) Justice Fellows may refer to: * Grant Fellows (1865–1929), associate justice of the Michigan Supreme Court * Raymond Fellows (1885–1957), associate justice of the Maine Supreme Judicial Court {{disambiguation, tndis ...
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Albany Medical College Alumni
Albany, derived from the Gaelic for Scotland, most commonly refers to: *Albany, New York, the capital of the State of New York and largest city of this name *Albany, Western Australia, port city in the Great Southern Albany may also refer to: Arts and music * "Albany" (1981), a German language schlager by the British singer Roger Whittaker * Albany Theatre (formerly the Albany Empire), in Deptford, South London, England Organizations and institutions England * Albany Academy, Chorley * Hornchurch High School, London, formerly The Albany School United States Georgia * Albany Movement, desegregation coalition formed in Albany, Georgia in 1961 * Albany State University, Albany New York * Albany Great Danes, the athletic program of the University at Albany * Albany Records, a record label in Albany * Albany Symphony Orchestra * University at Albany, SUNY People * Albany Leon Bigard, better known as Barney Bigard, a jazz musician * Duke of Albany, a Scottish, and later, Briti ...
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Binghamton University Alumni
Binghamton () is a city in the U.S. state of New York, and serves as the county seat of Broome County. Surrounded by rolling hills, it lies in the state's Southern Tier region near the Pennsylvania border, in a bowl-shaped valley at the confluence of the Susquehanna and Chenango Rivers. Binghamton is the principal city and cultural center of the Binghamton metropolitan area (also known as Greater Binghamton, or historically the Triple Cities, including Endicott and Johnson City), home to a quarter million people. The city's population, according to the 2020 census, is 47,969. From the days of the railroad, Binghamton was a transportation crossroads and a manufacturing center, and has been known at different times for the production of cigars, shoes, and computers. IBM was founded nearby, and the flight simulator was invented in the city, leading to a notable concentration of electronics- and defense-oriented firms. This sustained economic prosperity earned Binghamton the mon ...
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Drexel University Faculty
Drexel may refer to: People * Drexel (name) Places * Drexel, Missouri * Drexel, North Carolina * Drexel, Ohio * Drexel Hill, Pennsylvania Other uses * Disappearance of Brittanee Drexel * Drexel Heritage, a furniture manufacturer * Drexel University * Drexel Burnham Lambert, a now defunct investment bank * Drexel Dragons, the athletic program of Drexel University * The Drexel Collection of books about music and musical scores donated by Joseph William Drexel to The New York Public Library in 1888 ** Drexel 4041, a 17th-century British music manuscript commonplace book ** Drexel 4257 Drexel 4257, also known by an inscription on its first page, " John Gamble, his booke, amen 1659" is a music manuscript commonplace book. It is the largest collection of English songs from the first half to the middle of the 17th century, and is ..., a 17th-century British music manuscript commonplace book See also * Drexler {{disambiguation, geo ...
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American Biochemists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * ...
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calenda ...
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Sirolimus
Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumor ( PEComa). It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It is a mechanistic target of rapamycin kinase (mTOR) inhibitor that inhibits activation of T cells and B cells by reducing their sensitivity to interleukin-2 (IL-2). It is produced by the bacterium ''Streptomyces hygroscopicus'' and was isolated for the first time in 1972, from samples of ''Streptomyces hygroscopicus'' found on Easter Island. The compound was originally named rapamycin after the native name of the island, Rapa Nui. Sirolimus was initially developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent im ...
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Albany Medical College
Albany Medical College (AMC) is a private medical school in Albany, New York. It was founded in 1839 by Alden March and James H. Armsby and is one of the oldest medical schools in the nation. The college is part of the Albany Medical Center, which includes the Albany Medical Center Hospital. Along with Albany College of Pharmacy, Albany Law School, the Dudley Observatory, the Graduate College of Union University, and Union College, it is one of the constituent entities of Union University. Over its 170-year history, Albany Medical College has attracted and produced many leaders in medicine and research. Among its present and past faculty, researchers, and alumni there are two Nobel Prize winners, two Lasker Award winners, two MacArthur Fellowship recipients, one Gairdner Foundation International Award winner, former Surgeon General of the United States Army, former Surgeon General of the United States Air Force, several presidents and CEOs of major academic hospitals, as we ...
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Cellular Senescence
Cellular senescence is a phenomenon characterized by the cessation of cell division. In their experiments during the early 1960s, Leonard Hayflick and Paul Moorhead found that normal human fetal fibroblasts in culture reach a maximum of approximately 50 cell population doublings before becoming senescent. This process is known as "replicative senescence", or the Hayflick limit. Hayflick's discovery of mortal cells paved the path for the discovery and understanding of cellular aging molecular pathways. Cellular senescence can be initiated by a wide variety of stress inducing factors. These stress factors include both environmental and internal damaging events, abnormal cellular growth, oxidative stress, autophagy factors, among many other things. The physiological importance for cell senescence has been attributed to prevention of carcinogenesis, and more recently, aging, development, and tissue repair. Senescent cells contribute to the aging phenotype, including frailty syndr ...
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MTOR
The mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the ''MTOR'' gene. mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR links with other proteins and serves as a core component of two distinct protein complexes, mTOR complex 1 and mTOR complex 2, which regulate different cellular processes. In particular, as a core component of both complexes, mTOR functions as a serine/threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. As a core component of mTORC2, mTOR also functions as a tyrosine protein kinase that promotes the activation of insulin receptors and insulin-like growth factor 1 receptors. mTORC2 has also been implicated in the control and maintenance ...
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