Chlorfenvinfos
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Chlorfenvinfos
Chlorfenvinphos is the common name of an organophosphorus compound that was widely used as an insecticide and an acaricide. The molecule itself can be described as an enol ester derived from dichloro acetophenone and diethylphosphonic acid. Chlorfenvinphos has been included in many products since its first use in 1963. However, because of its toxic effect as a cholinesterase inhibitor it has been banned in several countries, including the United States and the European Union. Its use in the United States was cancelled in 1991. EFS. 1995. Reference Files System. Chemistry for chlorfenvinphos data report./ref> The pure chemical is a colorless solid, but for commercial purposes, it is often marketed as an amber liquid. The insecticides, mostly used in liquid form, contain between 50% and 90% chlorfenvinphos. The substance easily mixes with acetone, ethanol, and propylene glycol. Furthermore, chlorfenvinphos is corrosive to metal and hydrolyzes in the environment. .S. Department of ...
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List Of Extremely Hazardous Substances
This is the list of extremely hazardous substances defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002). The list can be found as an appendix to 40 C.F.R. 355. Updates as of 2006 can be seen on the Federal Register, 71 FR 47121 (August 16, 2006). The data were provided by the United States Environmental Protection Agency (EPA). __NOTOC__ A * Acetone cyanohydrin * Acetone thiosemicarbazide * Acrolein * Acrylamide * Acrylonitrile * Acryloyl chloride * Adiponitrile * Aldicarb * Aldrin * Allyl alcohol * Allylamine * Aluminum phosphide * Aminopterin * Amiton * Amiton oxalate * Ammonia * Amphetamine * Aniline * Aniline, 2,4,6-trimethyl- * Antimony pentafluoride * Antimycin A * ANTU (Alpha-Naphthylthiourea) * Arsenic pentoxide * Arsenous oxide * Arsenous trichloride * Arsine * Azinphos-ethyl * Azinphos-methyl B * Benzal chloride * Benzenamine, 3-(trifluoromethyl)- * Benzenearsonic acid * Benzimidazole, 4,5-dichloro-2-(tri ...
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Organophosphorus Compound
Organophosphorus compounds are organic compounds containing phosphorus. They are used primarily in pest control as an alternative to chlorinated hydrocarbons that persist in the environment. Some organophosphorus compounds are highly effective insecticides, although some are extremely toxic to humans, including sarin and VX nerve agents. Organophosphorus chemistry is the corresponding science of the properties and reactivity of organophosphorus compounds. Phosphorus, like nitrogen, is in group 15 of the periodic table, and thus phosphorus compounds and nitrogen compounds have many similar properties. The definition of organophosphorus compounds is variable, which can lead to confusion. In industrial and environmental chemistry, an organophosphorus compound need contain only an organic substituent, but need not have a direct phosphorus-carbon (P-C) bond. Thus a large proportion of pesticides (e.g., malathion), are often included in this class of compounds. Phosphorus can adopt ...
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Fly Spray
Fly spray is a chemical insecticide that comes in an aerosol can that is sprayed into the air to kill flies. Fly sprays will kill various insects such as house flies and wasps. Principles Fly spray contains chemicals (including many organophosphate compounds) that bind to and permanently block the action of an enzyme called acetylcholinesterase. Acetyl choline (ACh) is the nerve transmitter substance released by motor neurones (at a site called the neuromuscular junction) to stimulate muscle contraction. The muscles relax (stop contracting) when the ACh is removed from the neuromuscular junction (NMJ) by the action of acetylcholinesterase. By inhibiting the cholinesterase the insect can no longer break down ACh in the NMJ and so its muscles lock up in a state of tetany (continuous contraction) making flying and respiration impossible, and the insect then dies of asphyxiation. The Fly spray is shown to be effective against black flies. The U.S. Environmental Protection Agency ...
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Cytochrome P450
Cytochromes P450 (CYPs) are a Protein superfamily, superfamily of enzymes containing heme as a cofactor (biochemistry), cofactor that functions as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance (pharmacology), clearance of various compounds, as well as for hormone synthesis and breakdown. In 1963, Ronald W. Estabrook, Estabrook, David Y. Cooper, Cooper, and Otto Rosenthal, Rosenthal described the role of CYP as a catalyst in steroid hormone synthesis and drug metabolism. In plants, these proteins are important for the biosynthesis of secondary metabolite, defensive compounds, fatty acids, and hormones. CYP enzymes have been identified in all kingdom (biology), kingdoms of life: animals, plants, fungus, fungi, protists, bacteria, and archaea, as well as in viruses. However, they are not omnipresent; for example, they have not been found in ''Escherichia coli''. , more than 300,000 distinct CYP proteins ...
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Toxics Release Inventory
The Toxics Release Inventory (TRI) is a publicly available database containing information on toxic chemical releases and other waste management activities in the United States. Summary of requirements The database is available from the United States Environmental Protection Agency (EPA) and contains information reported annually by some industry groups as well as federal facilities. Each year, companies across a wide range of industries (including chemical manufacturing, metal mining, coal- or oil-burning electric utilities, and other industries) that manufacture, process, or otherwise use more than a certain amount of a listed chemical must report it to the TRI. For most listed chemicals, facilities must report if they manufacture 25,000 pounds or process or otherwise use 10,000 pounds of the chemical, but some chemicals have lower reporting thresholds. Origins The inventory was first proposed in a 1985 ''New York Times'' op-ed piece written by David Sarokin and Warren Muir, r ...
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Triethylphosphite
Triethyl phosphite is an organophosphorus compound with the formula P(OCH2CH3)3, often abbreviated P(OEt)3. It is a colorless, malodorous liquid. It is used as a ligand in organometallic chemistry and as a reagent in organic synthesis The molecule features a pyramidal phosphorus(III) center bound to three ethoxide groups. Its 31P NMR spectrum features a signal at around +139 ppm vs phosphoric acid standard. Triethylphosphite is prepared by treating phosphorus trichloride with ethanol in the presence of a base, typically a tertiary amine: :PCl3 + 3 EtOH + 3 R3N → P(OEt)3 + 3 R3NH + Cl− In the absence of the base, the reaction affords diethylphosphite ((EtO)2P(O)H). Of the many related compounds can be prepared similarly, triisopropyl phosphite is an example (b.p. 43.5 °C/1.0 mm; CAS# 116-17-6). As a ligand In coordination chemistry and homogeneous catalysis, triethylphosphite finds use as a soft ligand. Its complexes are generally lipophilic and feature met ...
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American Cyanamid Company
American Cyanamid Company was a leading American conglomerate which became one of the nation's top 100 manufacturing companies during the 1970s and 1980s, according to the Fortune 500 listings at the time. It started in fertilizer, but added many other lines of business. In merged with American Home Products in 1994. The combined company sold off most of its lines of business except pharmaceuticals, adopted the name of its remaining Wyeth division, and was bought by Pfizer in 2009, becoming defunct as a separate concern. History The company was founded by engineers Frank S. Washburn and Charles H. Baker in New York City in 1907, to capitalize on a German patent they had licensed for the manufacture of nitrogen products for fertilizer. The company's name is derived from the chemical ''calcium cyanamide'', the fertilizer they would manufacture. They soon set up headquarters in Nashville, investing a million dollars in several corporations underpinning the manufacturing operatio ...
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Allied Chemical Corporation
Allied Corp. was a major American company with operations in the chemical, aerospace, automotive, oil and gas industries. It was initially formed in 1920 as the Allied Chemical and Dye Corporation as an amalgamation of five chemical companies. In 1958, it was renamed Allied Chemical Corporation when it diversified into oil and gas exploration. Allied Chemical then became Allied Corporation in 1981. In 1985, Allied merged with the Signal Companies to become AlliedSignal. AlliedSignal would eventually acquire Honeywell in 1999 and then adopt its name. History During World War I, Imperial Germany controlled much of the world's chemical production. This resulted in critical shortages of certain dyes, drugs and especially ammonia, a vital compound used to make fertilizers and explosives. Allied Chemical and Dye Corporation In 1920, publisher Eugene Meyer and noted chemist William Ripley Nichols founded Allied Chemical and Dye Corporation in order to address this shortcoming in ...
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Royal Dutch Shell
Shell plc is a British multinational oil and gas company headquartered in London, England. Shell is a public limited company with a primary listing on the London Stock Exchange (LSE) and secondary listings on Euronext Amsterdam and the New York Stock Exchange. It is one of the oil and gas "supermajors" and by revenue and profits is consistently one of the largest companies in the world. Measured by both its own emissions, and the emissions of all the fossil fuels it sells, Shell was the ninth-largest corporate producer of greenhouse gas emissions in the period 1988–2015. Shell was formed in 1907 through the merger of Royal Dutch Petroleum Company of the Netherlands and The "Shell" Transport and Trading Company of the United Kingdom. The combined company rapidly became the leading competitor of the American Standard Oil and by 1920 Shell was the largest producer of oil in the world. Shell first entered the chemicals industry in 1929. Shell was one of the " Seven Sisters" whi ...
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Veterinary Medicine
Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in animals. Along with this, it deals with animal rearing, husbandry, breeding, research on nutrition, and product development. The scope of veterinary medicine is wide, covering all animal species, both domesticated and wild, with a wide range of conditions that can affect different species. Veterinary medicine is widely practiced, both with and without professional supervision. Professional care is most often led by a veterinary physician (also known as a veterinarian, veterinary surgeon, or "vet"), but also by paraveterinary workers, such as veterinary nurses or technicians. This can be augmented by other paraprofessionals with specific specialties, such as animal physiotherapy or dentistry, and species-relevant roles such as farriers. Veterinary science helps human health through the monitoring and control of zoonotic disease ...
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Inhalation Exposure
Inhalation is a major route of exposure that occurs when an individual breathes in polluted air which enters the respiratory tract. Identification of the pollutant uptake by the respiratory system can determine how the resulting exposure contributes to the dose. In this way, the mechanism of pollutant uptake by the respiratory system can be used to predict potential health impacts within the human population. Definition Exposure is commonly understood to be the concentration of the airborne pollutant in the air at the mouth and nose boundary. Outdoor concentrations are often measured at fixed sites or estimated with models. The fraction of this ambient concentration that is inhaled by a person depends mainly on their location (indoor or outdoor), distance to pollution sources and their minute ventilation. Traditionally exposure is estimated based on outdoor concentrations at the residential address. Trips to other locations and physical activity level are mostly neglected alth ...
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Toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word toxic. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Toxins are largely secondary metabolites, which are organic compounds that are not directly involved in an organism's growth, development, or reproduction, instead often aiding it in matters of defense. Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Le ...
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