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China–Cornell–Oxford Project
The China–Cornell–Oxford Project, short for the "China-Oxford-Cornell Study on Dietary, Lifestyle and Disease Mortality Characteristics in 65 Rural Chinese Counties," was a large observational study conducted throughout the 1980s in rural China, a partnership between Cornell University, the University of Oxford, and the government of China. The study compared the health consequences of diets rich in animal-based foods to diets rich in plant-based foods among people who were genetically similar. In May 1990, ''The New York Times'' termed the study "the Grand Prix of epidemiology". Background The idea for the study began in 1980–81 during discussions between T. Colin Campbell at Cornell University and Chen Junshi, Deputy Director of Institute of Nutrition and Food Hygiene at the Chinese Academy of Preventive Medicine. They were later joined by Richard Peto of the University of Oxford—Professor of Medical Statistics and Epidemiology as of 2012—and Li Junyao of the China C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Observational Study
In fields such as epidemiology, social sciences, psychology and statistics, an observational study draws inferences from a sample (statistics), sample to a statistical population, population where the dependent and independent variables, independent variable is not under the Scientific control, control of the researcher because of ethical concerns or logistical constraints. One common observational study is about the possible effect of a treatment on subjects, where the assignment of subjects into a treated group versus a control group is outside the control of the investigator. This is in contrast with experiments, such as randomized controlled trials, where each subject is Random assignment, randomly assigned to a treated group or a control group. Observational studies, for lacking an assignment mechanism, naturally present difficulties for inferential analysis. Motivation The independent variable may be beyond the control of the investigator for a variety of reasons: * A ran ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Peto
Sir Richard Peto (born 14 May 1943) is an English statistician and epidemiologist who is Professor of Medical Statistics and Epidemiology at the University of Oxford, England. Education He attended Taunton's School in Southampton and subsequently studied the Natural Sciences Tripos at Trinity College, Cambridge followed by a Master of Science degree in Statistics at Imperial College London. Career and research His career has included collaborations with Richard Doll beginning at the Medical Research Council Statistical Research Unit in London. He set up the Clinical Trial Service Unit (CTSU) in Oxford in 1975 and is currently co-director. Peto's paradox is named after him. Awards and honours He was elected a Fellow of the Royal Society in 1989 for his contributions to the development of meta-analysis. He is a leading expert on deaths related to tobacco use. "When Sir Richard Peto began work with the late Richard Doll fifty years ago, the UK had the worst death rates from s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health In China
Health in China over the course of the twentieth century has gone from being a largely private and family concern, using traditional medicine, to being a major concern of the state as well. Beginning in 1905, the Qing dynasty established the first Department of Health. The Republic of China after 1912 moved to expand public health measures and to control and license medical doctors. Governments debated the value of Chinese traditional or "folk" medicine, and moved toward Western healthcare models, especially after the Chinese Nationalist Party came to power in 1928 and during the Second Sino-Japanese War (1937-1945). China's health system has undergone basic changes since the Chinese Communist Revolution and declaration of the People's Republic of China in 1949. From 1949 until 1976, the Ministry of Health in Beijing and provincial ministries set policy and supported medical training, but primary responsibility for health care and public health lay with the work-unit, that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidemiological Study Projects
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. Epid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1980s In China
__NOTOC__ Year 198 (CXCVIII) was a common year starting on Sunday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Sergius and Gallus (or, less frequently, year 951 ''Ab urbe condita''). The denomination 198 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire *January 28 **Publius Septimius Geta, son of Septimius Severus, receives the title of Caesar (title), Caesar. **Caracalla, son of Septimius Severus, is given the title of Augustus (title), Augustus. China *Winter – Battle of Xiapi: The allied armies led by Cao Cao and Liu Bei defeat Lü Bu; afterward Cao Cao has him executed. By topic Religion * Marcus I of Byzantium, Marcus I succeeds Olympianus of Byzantium, Olympianus as Ecumenical Patriarch of Constantinople, Patriarch of Constantinople (until 211). ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Framingham Heart Study
The Framingham Heart Study is a long-term, ongoing cardiovascular cohort study of residents of the city of Framingham, Massachusetts. The study began in 1948 with 5,209 adult subjects from Framingham, and is now on its third generation of participants. Prior to the study almost nothing was known about the epidemiology of hypertensive or arteriosclerotic cardiovascular disease. Much of the now-common knowledge concerning heart disease, such as the effects of diet, exercise, and common medications such as aspirin, is based on this longitudinal study. It is a project of the National Heart, Lung, and Blood Institute, in collaboration with (since 1971) Boston University. Various health professionals from the hospitals and universities of Greater Boston staff the project. History In 1948, the study was commissioned by Congress, with a choice made between Framingham, Massachusetts and Paintsville, Kentucky. Framingham was chosen when residents showed more general interest in heart rese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caerphilly Heart Disease Study
The Caerphilly Heart Disease Study, also known as the Caerphilly Prospective Study (CaPS), is an epidemiological prospective cohort, set up in 1979 in a representative population sample drawn from Caerphilly, a typical small town in South Wales, UK. The initial aim was to examine relationships between a wide range of social, lifestyle, dietary and other factors with incident vascular disease. Opportunity was also taken, in collaboration with a range of clinical and laboratory colleagues, to collect data on a wide range of factors with possible relevance to diseases other than vascular, and at the same time to collect clinical information on incident disease events. The study was initiated by Professor Peter Elwood OBE, Director of the Medical Research Council (MRC) Epidemiology Unit for South Wales. The work has so far led to over 400 publications in the medical press. History In 1948, an MRC epidemiological unit was set up in Cardiff, South Wales, under Professor Archie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Busselton Health Study
__NOTOC__ The Busselton Health Study is a long-term , on-going health cohort study of residents of the Western Australian city of Busselton. Over 20,000 Busselton residents have participated in surveys concerning such health topics as cardiovascular disease, pulmonary function, diabetes, and cancer, resulting in over 400 publications. The program was initiated by Kevin Cullen, a local general practitioner, and is administered by the Busselton Population Medical Research Institute, which was established in 2000 as the Busselton Population Medical Research Foundation, and the School of Population and Global Health, University of Western Australia. Data from the study was used in a 1996 paper in ''Nature'' showing some of the first genetic links to asthma, along with a 1999 paper in the ''New England Journal of Medicine'' that was the first to describe the impact of the newly discovered HFE gene causing HFE hereditary haemochromatosis on a population with normal rates of sympt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The China Study
''The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health'' is a book by T. Colin Campbell and his son, Thomas M. Campbell II. The book argues for health benefits of a whole food plant-based diet. It was first published in the United States in January 2005 and had sold over one million copies as of October 2013, making it one of America's best-selling books about nutrition. Synopsis ''The China Study'' examines the link between the consumption of animal products (including dairy) and chronic illnesses such as Coronary artery disease, coronary heart disease, diabetes, breast cancer, prostate cancer, and bowel cancer. The book is "loosely based" on the China–Cornell–Oxford Project, a 20-year study which looked at mortality rates from cancer and other chronic diseases from 1973 to 1975 in 65 counties in China, and correlated this data with 1983–84 dietary surveys and blood work fro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rural Society In China
Rural society in the People's Republic of China encompasses less than half of China's population (roughly 45%) and has a varied range of standard of living and means of living. Life in rural China differs from that of urban China. In southern and coastal China, rural areas are developing and, in some cases, statistically approaching urban economies. In northwest and western regions, rural society is still perceived as lowly and primitive. Basic needs such as running water and accessible transportation are a problem in these areas. History Founding of the People's Republic One of the major avowed objectives of the Communist Party of China (CPC) during its rise to prominence between 1921 and 1949 was the improvement of the standard of living of the average Chinese citizen, the vast majority of whom were rural dwellers. During the pre-1936 period, the CPC played a major role in transforming rural life in areas it influenced or controlled. A major area was land reform, where contr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Distance
Genetic distance is a measure of the genetic divergence between species or between populations within a species, whether the distance measures time from common ancestor or degree of differentiation. Populations with many similar alleles have small genetic distances. This indicates that they are closely related and have a recent common ancestor. Genetic distance is useful for reconstructing the history of populations, such as the multiple human expansions out of Africa. It is also used for understanding the origin of biodiversity. For example, the genetic distances between different breeds of domesticated animals are often investigated in order to determine which breeds should be protected to maintain genetic diversity. Biological foundation In the genome of an organism, each gene is located at a specific place called the locus for that gene. Allelic variations at these loci cause phenotypic variation within species (e.g. hair colour, eye colour). However, most alleles do not hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
