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Chihuahua (dog)
The Chihuahua or es, Chihuahueño, italic=no is a Mexican breed of toy dog. It is named for the Mexican state of Chihuahua and is among the smallest of all dog breeds. It is usually kept as a companion animal or for showing. History DNA studies suggest that native American dogs entered North America from Siberia roughly 10,000 years ago, and were then isolated for some 9000 years until the arrival of the first Europeans; these pre-contact dogs exhibited a unique genetic signature that is now almost gone. A study based on sequencing of ancient dog genomes, published in 2020, suggests that this pre-colonial ancestry survives in two Mexican breeds, to the extent of about 4% in the Chihuahua (and some 3% in the Xoloitzcuintli). Colonial records refer to small, nearly hairless dogs at the beginning of the nineteenth century; one claims that sixteenth-century conquistadores found them plentiful in the region later known as Chihuahua. In a letter written in 1520, Hernan Cor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Dog Breeds
This list of dog breeds includes both Neontology#Extant taxa versus extinct taxa, extant and extinct dog breeds, Designer breed, varieties, landraces, and dog types. A research article on genomics, dog genomics published in Science/AAAS defines modern dog breeds as "a recent invention defined by conformation to a physical ideal and purity of lineage". Extant breeds, landraces, varieties and types Note: not all dogs listed below are recognized breeds by an official breed registry that can certify the dog is a purebred, including The Kennel Club (TKC - 1873), the oldest and first official dog breed registry in the world, located in the United Kingdom, and the three oldest breed registries in North America, and largest in the world, including the American Kennel Club (AKC - 1884), United Kennel Club (UKC - 1898), and Canadian Kennel Club (CKC - 1888). A–C D–K L–R S–Z Extinct breeds, landraces, varieties and types Notes References Citations Bib ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conformation Show
A dog show is an event where dogs are exhibited. A conformation show, also referred to as a ''breed show'', is a kind of dog show in which a judge, familiar with a specific dog breed, evaluates individual purebred dogs for how well the dogs ''conform'' to the established breed type for their breed, as described in a breed's individual breed standard. Such shows are useful to breeders as a means of evaluating dogs for breeding purposes. A conformation championship from a recognised national kennel club is generally considered a reasonably objective indication of merit, as it indicates that the dog has been found to be a superior example of its breed by a number of different judges on a number of separate occasions. Many breeders consider championship a prerequisite for breeding. Conformation shows have been controversial, as critics argue that the shows encourage selective breeding of traits and lower genetic diversity, which reduces the health, happiness and longevity of the do ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radiographical
Radiography is an imaging technique using X-rays, gamma rays, or similar ionizing radiation and non-ionizing radiation to view the internal form of an object. Applications of radiography include medical radiography ("diagnostic" and "therapeutic") and industrial radiography. Similar techniques are used in airport security (where "body scanners" generally use backscatter X-ray). To create an image in conventional radiography, a beam of X-rays is produced by an X-ray generator and is projected toward the object. A certain amount of the X-rays or other radiation is absorbed by the object, dependent on the object's density and structural composition. The X-rays that pass through the object are captured behind the object by a detector (either photographic film or a digital detector). The generation of flat two dimensional images by this technique is called projectional radiography. In computed tomography (CT scanning) an X-ray source and its associated detectors rotate around the sub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroaxonal Dystrophy
Infantile neuroaxonal dystrophy is a rare pervasive developmental disorder that primarily affects the nervous system. Individuals with infantile neuroaxonal dystrophy typically do not have any symptoms at birth, but between the ages of about 6 and 18 months they begin to experience delays in acquiring new motor and intellectual skills, such as crawling or beginning to speak. Eventually they lose previously acquired skills. Cause This condition is inherited in an autosomal recessive pattern, which means two copies of the gene (''PLA2G6'') in each cell are altered. Most often, the parents of an individual with an autosomal recessive disorder each carry one copy of the altered gene but do not show signs and symptoms of the disorder. Pathophysiology Mutations in the ''PLA2G6'' gene have been identified in most individuals with infantile neuroaxonal dystrophy. The ''PLA2G6'' gene provides instructions for making an enzyme called an A2 phospholipase. This enzyme family is involved i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Necrotizing Meningoencephalitis
Necrotizing meningoencephalitis (NME) is a fatal inflammatory central nervous system (CNS) disorder, where an extensive cerebral necrosis is associated with a multifocal, non-suppurative meningoencephalitis of the neuro cortex. It was originally identified and recorded in the 1960s in pure breed pugs, with which this disease is nowadays mostly associated with, occurring essentially in small breed dogs ranging from six months to seven years of age. It causes intense necrotizing inflammatory lesions in the brain stem and Cerebellum. Thetiopathologyis still unclear. The pathogen that triggers the disease and contributes to its development has not yet been identified. It is presumed to have a multifactorial, heritable, autoimmune etiology. The process is rapidly progressive, culminating in status epilepticus and ending fatally for the dog. Although the pattern of inflammation is similar to other neuropathological conditions, resembling CNS inflammatory diseases which produces lesions al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Muscular Dystrophy
Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time. The disorders differ as to which muscles are primarily affected, the degree of weakness, how fast they worsen, and when symptoms begin. Some types are also associated with problems in other organs. Over 30 different disorders are classified as muscular dystrophies. Of those, Duchenne muscular dystrophy (DMD) accounts for approximately 50% of cases and affects males beginning around the age of four. Other relatively common muscular dystrophies include Becker muscular dystrophy, facioscapulohumeral muscular dystrophy, and myotonic dystrophy, whereas limb–girdle muscular dystrophy and congenital muscular dystrophy are themselves groups of several – usually ultrarare – genetic disorders. Muscular dystrophies are caused by mutations in genes, usually those involved in making muscle proteins. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Hydrocephalus
Hydrocephalus is a condition in which an accumulation of cerebrospinal fluid (CSF) occurs within the brain. This typically causes increased pressure inside the skull. Older people may have headaches, double vision, poor balance, urinary incontinence, personality changes, or mental impairment. In babies, it may be seen as a rapid increase in head size. Other symptoms may include vomiting, sleepiness, seizures, and downward pointing of the eyes. Hydrocephalus can occur due to birth defects or be acquired later in life. Associated birth defects include neural tube defects and those that result in aqueductal stenosis. Other causes include meningitis, brain tumors, traumatic brain injury, intraventricular hemorrhage, and subarachnoid hemorrhage. The four types of hydrocephalus are communicating, noncommunicating, ''ex vacuo'', and normal pressure. Diagnosis is typically made by physical examination and medical imaging. Hydrocephalus is typically treated by the surgical placeme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Deafness
Hearing loss is a partial or total inability to hear. Hearing loss may be present at birth or acquired at any time afterwards. Hearing loss may occur in one or both ears. In children, hearing problems can affect the ability to acquire spoken language, and in adults it can create difficulties with social interaction and at work. Hearing loss can be temporary or permanent. Hearing loss related to age usually affects both ears and is due to cochlear hair cell loss. In some people, particularly older people, hearing loss can result in loneliness. Deaf people usually have little to no hearing. Hearing loss may be caused by a number of factors, including: genetics, ageing, exposure to noise, some infections, birth complications, trauma to the ear, and certain medications or toxins. A common condition that results in hearing loss is chronic ear infections. Certain infections during pregnancy, such as cytomegalovirus, syphilis and rubella, may also cause hearing loss in the child. He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ceroid Lipofuscinosis
Neuronal ceroid lipofuscinosis is the general name for a family of at least eight genetically separate neurodegenerative lysosomal storage diseases that result from excessive accumulation of lipopigments (lipofuscin) in the body's tissues. These lipopigments are made up of fats and proteins. Their name comes from the word stem "lipo-", which is a variation on lipid, and from the term "pigment", used because the substances take on a greenish-yellow color when viewed under an ultraviolet light microscope. These lipofuscin materials build up in neuronal cells and many organs, including the liver, spleen, myocardium, and kidneys. Signs and symptoms The classic characterization of the group of neurodegenerative, lysosomal storage disorders called the neuronal ceroid lipofuscinoses (NCLs) is through the progressive, permanent loss of motor and psychological ability with a severe intracellular accumulation of lipofuscins, with the United States and Northern European populations having sli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atlantoaxial Instability
In anatomy, the transverse ligament of the atlas is a ligament which arches across the ring of the atlas (the topmost cervical vertebra, which directly supports the skull), and keeps the odontoid process in contact with the atlas. Anatomy It is concave in front, convex behind, broader and thicker in the middle than at the ends, and firmly attached on either side to a small tubercle on the medial surface of the lateral mass of the atlas.Gray's anatomy, 1918 As it crosses the odontoid process, a small fasciculus (''crus superius'') is prolonged upward, and another (''crus inferius'') downward, from the superficial or posterior fibers of the ligament. The former is attached to the basilar part of the occipital bone, in close relation with the membrana tectoria; the latter is fixed to the posterior surface of the body of the axis; hence, the whole ligament is named the cruciate ligament of the atlas. The transverse ligament divides the ring of the atlas into two unequal parts: of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurological Disease
A neurological disorder is any disorder of the nervous system. Structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves can result in a range of symptoms. Examples of symptoms include paralysis, muscle weakness, poor coordination, loss of sensation, seizures, confusion, pain and altered levels of consciousness. There are many recognized neurological disorders, some relatively common, but many rare. They may be assessed by neurological examination, and studied and treated within the specialities of neurology and clinical neuropsychology. Interventions foneurological disordersinclude preventive measures, lifestyle changes, physiotherapy or other therapy, neurorehabilitation, pain management, medication, operations performed by neurosurgeons or a specific diet. The World Health Organization estimated in 2006 that neurological disorders and their sequelae (direct consequences) affect as many as one billion people worldwide, and identified heal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Predisposition
A genetic predisposition is a genetic characteristic which influences the possible phenotypic development of an individual organism within a species or population under the influence of environmental conditions. In medicine, genetic susceptibility to a disease refers to a genetic predisposition to a health problem, which may eventually be triggered by particular environmental or lifestyle factors, such as tobacco smoking or diet. Genetic testing is able to identify individuals who are genetically predisposed to certain diseases. Behavior Predisposition is the capacity humans are born with to learn things such as language and concept of self. Negative environmental influences may block the predisposition (ability) one has to do some things. Behaviors displayed by animals can be influenced by genetic predispositions. Genetic predisposition towards certain human behaviors is scientifically investigated by attempts to identify patterns of human behavior that seem to be invariant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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