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Cherenkov Luminescence Imaging
Cherenkov luminescence imaging (CLI) is an emerging imaging modality, similar to bioluminescence imaging Bioluminescence imaging (BLI) is a technology developed over the past decade that allows for the noninvasive study of ongoing biological processes. Recently, bioluminescence tomography (BLT) has become possible and several systems have become com ..., that captures visible photons emitted by Cherenkov radiation. It basically is the optical imaging of radiotracers that emit charged particles traveling faster than the phase velocity of light in that particular medium. It can be used to quickly evaluate radio tracers in preclinical research but also to obtain clinical images in patients. While radioactivity itself can not be modified, the emitted light provides an opportunity to generate radioactivity-based activatable or "smart" imaging agents that sense for example enzymatic activity. References * External links * Imaging {{measurement-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioluminescence Imaging
Bioluminescence imaging (BLI) is a technology developed over the past decade that allows for the noninvasive study of ongoing biological processes. Recently, bioluminescence tomography (BLT) has become possible and several systems have become commercially available. In 2011, PerkinElmer acquired one of the most popular lines of optical imaging systems with bioluminescence from Caliper Life Sciences. Background Bioluminescence is the process of light emission in living organisms. Bioluminescence imaging utilizes native light emission from one of several organisms which bioluminesce. The three main sources are the North American firefly, the sea pansy (and related marine organisms), and bacteria like ''Photorhabdus luminescens'' and ''Vibrio fischeri''. The DNA encoding the luminescent protein is incorporated into the laboratory animal either via a viral vector or by creating a transgenic animal. Rodent models of cancer spread can be studied through bioluminescence imaging.for e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philosophical Transactions Of The Royal Society A
''Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences'' is a fortnightly peer-reviewed scientific journal published by the Royal Society. It publishes original research and review content in a wide range of physical scientific disciplines. Articles can be accessed online a few months prior to the printed journal. All articles become freely accessible two years after their publication date. The current editor-in-chief is John Dainton. Overview ''Philosophical Transactions of the Royal Society A'' publishes themed journal issues on topics of current scientific importance and general interest within the physical, mathematical and engineering sciences, edited by leading authorities and comprising original research, reviews and opinions from prominent researchers. Past issue titles include "Supercritical fluids - green solvents for green chemistry?", "Tsunamis: Bridging science, engineering and society", "Spatial transformations: from f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |