Charles V. Shank
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Charles V. Shank
Charles Vernon (Chuck) Shank (born July 12, 1943) is an American physicist, best known as the director of the Lawrence Berkeley National Laboratory from 1989 to 2004. Early life and education Charles Vernon (Chuck) Shank was born in Mount Holly, New Jersey, on July 12, 1943. He entered the University of California, Berkeley, where he earned his Bachelor of Science (B.S.) degree in 1965, his Master of Science (M.S.) in 1966, and his Doctor of Philosophy (Ph.D.) in 1969, all in electrical engineering, writing his doctoral thesis on "Nonlinear Wave Interaction Spectroscopy", under the supervision of Steven E. Schwartz. Career After graduation, Shank joined the staff of the Bell Laboratories as a researcher. He would remain there for 20 years, becoming head of its Quantum Physics and Electronic Research Department in 1976, and director of its Electronics Research Laboratory in 1983. Shank introduced the use of short laser pulses to study ultrafast events, ones that take place in a ...
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Mount Holly, New Jersey
Mount Holly is a township that is the county seat of Burlington County in the U.S. state of New Jersey. It is an eastern suburb of Philadelphia, the nation's sixth largest city as of 2020, As of the 2020 U.S. census, the township's population was 9,981. What is now Mount Holly was originally formed as Northampton on November 6, 1688. Northampton was incorporated as one of New Jersey's initial group of 104 townships created by an act of the New Jersey Legislature on February 21, 1798. Portions of the township were taken to form Little Egg Harbor Township (February 13, 1740, now part of Ocean County), Washington Township (November 19, 1802), Pemberton borough (December 15, 1826), Coaxen Township (March 10, 1845, now known as Southampton Township), Pemberton Township (March 10, 1846), Westampton Township (March 6, 1850) and Lumberton Township (March 14, 1860). The township was renamed Mount Holly as of November 6, 1931, based on the results of a referendum held three days e ...
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Ultrafast Science
In optics, an ultrashort pulse, also known as an ultrafast event, is an electromagnetic pulse whose time duration is of the order of a picosecond (10−12 second) or less. Such pulses have a broadband optical spectrum, and can be created by mode-locked oscillators. Amplification of ultrashort pulses almost always requires the technique of chirped pulse amplification, in order to avoid damage to the gain medium of the amplifier. They are characterized by a high peak intensity (or more correctly, irradiance) that usually leads to nonlinear interactions in various materials, including air. These processes are studied in the field of nonlinear optics. In the specialized literature, "ultrashort" refers to the femtosecond (fs) and picosecond (ps) range, although such pulses no longer hold the record for the shortest pulses artificially generated. Indeed, x-ray pulses with durations on the attosecond time scale have been reported. The 1999 Nobel Prize in Chemistry was awarded ...
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Joint Dark Energy Mission
The Joint Dark Energy Mission (JDEM) was an Einstein probe that planned to focus on investigating dark energy. JDEM was a partnership between NASA and the U.S. Department of Energy (DOE). In August 2010, the Board on Physics and Astronomy of the National Science Foundation (NSF) recommended the Wide Field Infrared Survey Telescope (WFIRST) mission, a renamed JDEM-Omega proposal which has superseded SNAP, Destiny, and Advanced Dark Energy Physics Telescope (ADEPT), as the highest priority for development in the decade around 2020. This would be a 1.5-meter telescope with a 144-megapixel HgCdTe focal plane array, located at the Sun-Earth L2 Lagrange point. The expected cost is around US$1.6 billion. Earlier proposals Dark Energy Space Telescope (Destiny) The Dark Energy Space Telescope (Destiny), was a planned project by NASA and DOE, designed to perform precision measurements of the universe to provide an understanding of dark energy. The space telescope will derive t ...
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Chromosome 19 (human)
Chromosome 19 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 19 spans more than 58.6 million base pairs, the building material of DNA. It is considered the most gene-rich chromosome containing roughly 1,500 genes, despite accounting for only 2 percent of the human genome. Genes Number of genes The following are some of the gene count estimates of human chromosome 19. Because researchers use different approaches to genome annotation, their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project ( CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. Gene list The following is a partial list of genes on human chromosome 19. For complete list, see the link in the infobox on the right. ...
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Chromosome 16 (human)
Chromosome 16 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 16 spans about 90 million base pairs (the building material of DNA) and represents just under 3% of the total DNA in cells. Genes Number of genes The following are some of the gene count estimates of human chromosome 16. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project ( CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. Gene list The following is a partial list of genes on human chromosome 16. For complete list, see the link in the infobox on the right. Diseases and disorders *Attention deficit hyperactivity disorder (ADHD) *Asperger syndro ...
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Chromosome 5 (human)
Chromosome 5 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 5 spans about 181 million base pairs (the building blocks of DNA) and represents almost 6% of the total DNA in cells. Chromosome 5 is the 5th largest human chromosome, yet has one of the lowest gene densities. This is partially explained by numerous gene-poor regions that display a remarkable degree of non-coding and syntenic conservation with non-mammalian vertebrates, suggesting they are functionally constrained. Because chromosome 5 is responsible for many forms of growth and development (cell divisions) changes may cause cancers. One example would be acute myeloid leukemia (AML). Genes Number of genes The following are some of the gene count estimates of human chromosome 5. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction ...
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Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It remains the world's largest collaborative biological project. Planning started after the idea was picked up in 1984 by the US government, the project formally launched in 1990, and was declared essentially complete on April 14, 2003, but included only about 85% of the genome. Level "complete genome" was achieved in May 2021, with a remaining only 0.3% bases covered by potential issues. The final gapless assembly was finished in January 2022. Funding came from the United States government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by the ...
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Joint Genome Institute
The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), first located in Walnut Creek then Berkeley, California, was created in 1997 to unite the expertise and resources in genome mapping, DNA sequencing, technology development, and information sciences pioneered at the DOE genome centers at Lawrence Berkeley National Laboratory (Berkeley Lab), Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory (LANL). As a DOE Office of Science User Facility of Berkeley Lab, the JGI staff is composed of employees from Berkeley Lab, LLNL and the HudsonAlpha Institute for Biotechnology. The JGI also collaborates with other DOE-supported programs and facilities, such as the Environmental Molecular Sciences Laboratory at Pacific Northwest National Laboratory (PNNL), the National Energy Research Scientific Computing Center, or NERSC, and the DOE Bioenergy Research Centers. History In 1999, the University of California, which manages the three national labs for ...
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Los Alamos National Laboratory
Los Alamos National Laboratory (often shortened as Los Alamos and LANL) is one of the sixteen research and development laboratories of the United States Department of Energy (DOE), located a short distance northwest of Santa Fe, New Mexico, in the American southwest. Best known for its central role in helping develop the first atomic bomb, LANL is one of the world's largest and most advanced scientific institutions. Los Alamos was established in 1943 as Project Y, a top-secret site for designing nuclear weapons under the Manhattan Project during World War II.The site was variously called Los Alamos Laboratory and Los Alamos Scientific Laboratory. Chosen for its remote yet relatively accessible location, it served as the main hub for conducting and coordinating nuclear research, bringing together some of the world's most famous scientists, among them numerous Nobel Prize winners. The town of Los Alamos, directly north of the lab, grew extensively through this period. After ...
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Lawrence Livermore National Laboratory
Lawrence Livermore National Laboratory (LLNL) is a federal research facility in Livermore, California, United States. The lab was originally established as the University of California Radiation Laboratory, Livermore Branch in 1952 in response to the detonation of the first atomic bomb by the Soviet Union during the Cold War. It later became autonomous in 1971 and was designated a national laboratory in 1981. A federally funded research and development center, Lawrence Livermore Lab is primarily funded by the U.S. Department of Energy and it is managed privately and operated by Lawrence Livermore National Security, LLC (a partnership of the University of California), Bechtel, BWX Technologies, AECOM, and Battelle Memorial Institute in affiliation with the Texas A&M University System. In 2012, the laboratory had the synthetic chemical element livermorium (element 116) named after it. Overview LLNL is self-described as a "premier research and development institution for sci ...
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Supercomputing
A supercomputer is a computer with a high level of performance as compared to a general-purpose computer. The performance of a supercomputer is commonly measured in floating-point operations per second (FLOPS) instead of million instructions per second (MIPS). Since 2017, there have existed supercomputers which can perform over 1017 FLOPS (a hundred quadrillion FLOPS, 100 petaFLOPS or 100 PFLOPS). For comparison, a desktop computer has performance in the range of hundreds of gigaFLOPS (1011) to tens of teraFLOPS (1013). Since November 2017, all of the world's fastest 500 supercomputers run on Linux-based operating systems. Additional research is being conducted in the United States, the European Union, Taiwan, Japan, and China to build faster, more powerful and technologically superior exascale supercomputers. Supercomputers play an important role in the field of computational science, and are used for a wide range of computationally intensive tasks in vario ...
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National Energy Research Scientific Computing Center
The National Energy Research Scientific Computing Center (NERSC), is a high-performance computing (supercomputer) National User Facility operated by Lawrence Berkeley National Laboratory for the United States Department of Energy Office of Science. As the mission computing center for the Office of Science, NERSC houses high performance computing and data systems used by 9,000 scientists at national laboratories and universities around the country. NERSC's newest and largest supercomputer is Perlmutter (supercomputer), Perlmutter, which debuted in 2021 ranked 5th on the TOP500 list of world's fastest supercomputers. History NERSC was founded in 1974 as the Controlled Thermonuclear Research Computer Center, or CTRCC, at Lawrence Livermore National Laboratory. The center was created to provide computing resources to the fusion energy research community, and began with a Control Data Corporation 6600 computer (SN-1). The first machine procured directly by the center was a CDC 7600, in ...
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