Charles Alexander MacMunn
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Charles Alexander MacMunn
Dr Charles Alexander MacMunn (11 April 1852 – 18 February 1911) was the first to describe the respiratory pigment in blood, known today as Cytochrome1. It was one of the most significant discoveries made by an Irish doctor. Biography MacMunn was born on 11 April 1852 in Easkey, County Sligo, Ireland, the son of James MacMunn MD. He was educated at Trinity College Dublin, graduating BA with honours in 1871, MB in 1872, MD in 1875. He studied under William Stokes. He moved to Wolverhampton in 1873 to work within his cousin's practice, subsequently taking over the practice on his cousin's death. He had a loft of his stable converted to a laboratory work he could carry out work on his spectroscopy when not otherwise engaged with the practice. He was the author of numerous papers on medicine, physiology and biology. His seminal paper was published in 1880 entitled "The Spectroscope in Medicine". He used the spectroscope to study pigments in microorganisms and muscular tissue. ...
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Respiratory Pigment
A respiratory pigment is a metalloprotein that serves a variety of important functions, its main being O2 transport. Other functions performed include O2 storage, CO2 transport, and transportation of substances other than respiratory gases. There are four major classifications of respiratory pigment: hemoglobin, hemocyanin, erythrocruorin– chlorocruorin, and hemerythrin. The heme-containing globin is the most commonly-occurring respiratory pigment, occurring in at least 9 different phyla of animals. Comparing Respiratory Pigments Hemoglobin, erythrocruorin, and chlorocruorin are all globins, iron-heme proteins with a common core. Their color comes from the absorption spectra of heme with Fe2+. Erythrocruorin and chlorocruorin are closely related giant globins found used by some invertebrates. Chlorocruorin has a special heme group, giving it different colors. Globins The globin is thought to be a very ancient molecule, even acting as a molecular clock of sorts. It has ...
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Boer War
The Second Boer War ( af, Tweede Vryheidsoorlog, , 11 October 189931 May 1902), also known as the Boer War, the Anglo–Boer War, or the South African War, was a conflict fought between the British Empire and the two Boer Republics (the South African Republic and the Orange Free State) over the Empire's influence in Southern Africa from 1899 to 1902. Following the discovery of gold deposits in the Boer republics, there was a large influx of "foreigners", mostly British from the Cape Colony. They were not permitted to have a vote, and were regarded as "unwelcome visitors", invaders, and they protested to the British authorities in the Cape. Negotiations failed and, in the opening stages of the war, the Boers launched successful attacks against British outposts before being pushed back by imperial reinforcements. Though the British swiftly occupied the Boer republics, numerous Boers refused to accept defeat and engaged in guerrilla warfare. Eventually, British scorched e ...
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People From County Sligo
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
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Irish Military Doctors
Irish may refer to: Common meanings * Someone or something of, from, or related to: ** Ireland, an island situated off the north-western coast of continental Europe ***Éire, Irish language name for the isle ** Northern Ireland, a constituent unit of the United Kingdom of Great Britain and Northern Ireland ** Republic of Ireland, a sovereign state * Irish language, a Celtic Goidelic language of the Indo-European language family spoken in Ireland * Irish people, people of Irish ethnicity, people born in Ireland and people who hold Irish citizenship Places * Irish Creek (Kansas), a stream in Kansas * Irish Creek (South Dakota), a stream in South Dakota * Irish Lake, Watonwan County, Minnesota * Irish Sea, the body of water which separates the islands of Ireland and Great Britain People * Irish (surname), a list of people * William Irish, pseudonym of American writer Cornell Woolrich (1903–1968) * Irish Bob Murphy, Irish-American boxer Edwin Lee Conarty (1922–1961) * Irish ...
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1911 Deaths
A notable ongoing event was the Comparison of the Amundsen and Scott Expeditions, race for the South Pole. Events January * January 1 – A decade after federation, the Northern Territory and the Australian Capital Territory are added to the Commonwealth of Australia. * January 3 ** 1911 Kebin earthquake: An earthquake of 7.7 Moment magnitude scale, moment magnitude strikes near Almaty in Russian Turkestan, killing 450 or more people. ** Siege of Sidney Street in London: Two Latvian people, Latvian anarchists die, after a seven-hour siege against a combined police and military force. Home Secretary Winston Churchill arrives to oversee events. * January 5 – Egypt's Zamalek SC is founded as a general sports and Association football club by Belgian lawyer George Merzbach as Qasr El Nile Club. * January 14 – Roald Amundsen's South Pole expedition makes landfall, on the eastern edge of the Ross Ice Shelf. * January 18 – Eugene B. El ...
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1852 Births
Year 185 ( CLXXXV) was a common year starting on Friday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Lascivius and Atilius (or, less frequently, year 938 '' Ab urbe condita''). The denomination 185 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Nobles of Britain demand that Emperor Commodus rescind all power given to Tigidius Perennis, who is eventually executed. * Publius Helvius Pertinax is made governor of Britain and quells a mutiny of the British Roman legions who wanted him to become emperor. The disgruntled usurpers go on to attempt to assassinate the governor. * Tigidius Perennis, his family and many others are executed for conspiring against Commodus. * Commodus drains Rome's treasury to put on gladiatorial spectacles and confiscates property to su ...
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Institute Of Technology, Sligo
The Institute of Technology, Sligo (ITS; ga, Institiúid Teicneolaíochta, Sligeach) was an institute of technology, located in Sligo, Ireland. In April 2022, it was formally dissolved, and its functions became part of Atlantic Technological University (ATU). As of 2021, the institute had three faculties and nine departments. History The institute opened in 1970 as a Regional Technical College, and adopted its present name on 7 May 1997. The first students graduated with degrees from Sligo RTC in 1986. Con Power served as principal of the college from its foundation in 1972 until 1979. Prof. Terri Scott was the institute's first female president, serving from 2008 until 2014. She was succeeded by Prof. Vincent Cunnane in October 2014. Dr. Brendan McCormack was appointed president of the institute in September 2016. Development IT Sligo developed a number of distance learning options, and as of 2016 reportedly had 1,800 online learners registered on various online programmes ...
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Queen's South Africa Medal
The Queen's South Africa Medal is a British campaign medal awarded to British and Colonial military personnel, and to civilians employed in an official capacity, who served in the Second Boer War in South Africa. Altogether twenty-six clasps were awarded, to indicate participation in particular actions and campaigns. Institution The Queen's South Africa Medal was instituted by Queen Victoria in 1900, for award to military personnel and civilian officials who served in South Africa during the Second Boer War from 11 October 1899 to 31 May 1902.The Queen's South Africa Medal 1899 - 1902
Retrieved March 13, 2015.
Three versions of the medal are known. Since the war was initially expected to be of short duration and to reach its conclusion in 1900, the first medals were struck w ...
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David Keilin
David Keilin FRS (21 March 1887 – 27 February 1963) was a Jewish scientist focusing mainly on entomology. Background and education He was born in Moscow in 1887 and his family returned to Warsaw early in his youth. He did not attend school until age ten due to ill health and asthma. Only seven years later, in 1904, he enrolled in the University of Liège. He later studied at Magdalene College, Cambridge, and became a British citizen. Career Keilin became research assistant to George Nuttall, first Quick Professor of Biology at the University of Cambridge, in 1915, and spent the rest of his career there, succeeding Nuttall as Quick Professor and director of the Molteno Institute in 1931. He retired in 1952. He made extensive contributions to entomology and parasitology during his career. He published thirty-nine papers between 1914 and 1923 on the reproduction of lice, the life-cycle of the horse bot-fly, the respiratory adaptations in fly larvae, and other subjects. He ...
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Easkey
Easky or Easkey (; ) is a village in County Sligo, Ireland. It is on the Atlantic coast, from Sligo and from Ballina, County Mayo. The village name derives from the Irish language term for fish ("iasc") and "Iascaigh" literally means "abounding in fish", due to the Easky River that lies adjacent to the village itself. Easky, as a parish, was originally called "Imleach Iseal". The area is a tourist destination on account of its scenery and water sports. Easky is a designated area on Ireland's Wild Atlantic Way tourist route. History The parish of Easky is part of the barony of Tireragh. Tireragh is a corruption of '' Tír Fhíacrach Múaidhe'' in Irish, meaning "the land of Fiachra of the Moy". This tuath was founded by the Uí Fiachrach Muaidhe, who were, themselves, a branch of the Uí Fiachrach dynasty of Connachta. Easky was originally named "Imleach Iseal/Isil" which means the "low imleach", or "low land verging on the water". The first settlements in the area seem t ...
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Felix Hoppe-Seyler
Ernst Felix Immanuel Hoppe-Seyler (''né'' Felix Hoppe; 26 December 1825 – 10 August 1895) was a German physiologist and chemist, and the principal founder of the disciplines of biochemistry and molecular biology. Biography Hoppe-Seyler was born in Freyburg an der Unstrut in the Province of Saxony. He originally trained to be a physician in Halle and Leipzig, and received his medical doctorate from Berlin in 1851. Afterwards, he was an assistant to Rudolf Virchow at the Pathological Institute in Berlin. Hoppe-Seyler preferred scientific research to medicine, and later held positions in anatomy, applied chemistry, and physiological chemistry in Greifswald, Tübingen and Strasbourg. At Strasbourg, he was head of the department of biochemistry, the only such institution in Germany at the time. His work also led to advances in organic chemistry by his students and by immunologist Paul Ehrlich. Among his students and collaborators were Friedrich Miescher (1844–1895) and Nobel ...
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Cytochrome
Cytochromes are redox-active proteins containing a heme, with a central Fe atom at its core, as a cofactor. They are involved in electron transport chain and redox catalysis. They are classified according to the type of heme and its mode of binding. Four varieties are recognized by the International Union of Biochemistry and Molecular Biology (IUBMB), cytochromes a, cytochromes b, cytochromes c and cytochrome d. Cytochrome function is linked to the reversible redox change from ferrous (Fe(II)) to the ferric (Fe(III)) oxidation state of the iron found in the heme core. In addition to the classification by the IUBMB into four cytochrome classes, several additional classifications such as cytochrome o and cytochrome P450 can be found in biochemical literature. History Cytochromes were initially described in 1884 by Charles Alexander MacMunn as respiratory pigments (myohematin or histohematin). In the 1920s, Keilin rediscovered these respiratory pigments and named them the c ...
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