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Charged Aerosol Detector
The Charged Aerosol Detector (CAD) is a detector used in conjunction with high-performance liquid chromatography (HPLC) and ultra high-performance liquid chromatography (UHPLC) to measure the amount of chemicals in a sample by creating charged aerosol particles which are detected using an electrometer An electrometer is an electrical instrument for measuring electric charge or electrical potential difference. There are many different types, ranging from historical handmade mechanical instruments to high-precision electronic devices. Modern ....Gamache P. (2005HPLC analysis of nonvolatile analytes using charged aerosol detectionretrieved September 17, 2015. It is commonly used for the analysis of compounds that cannot be detected using traditional UV/Vis approaches due to their lack of a chromophore. The CAD can measure all non-volatile and many semi-volatile analytes including, but not limited to, antibiotics, excipients, ions, lipids, natural products, biofuels, sugars and su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
High-performance Liquid Chromatography
High-performance liquid chromatography (HPLC), formerly referred to as high-pressure liquid chromatography, is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out of the column. HPLC has been used for manufacturing (''e.g.'', during the production process of pharmaceutical and biological products), legal (''e.g.'', detecting performance enhancement drugs in urine), research (''e.g.'', separating the components of a complex biological sample, or of similar synthetic chemicals from each other), and medical (''e.g.'', detecting vitamin D levels in blood serum) purposes. Chrom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrometer
An electrometer is an electrical instrument for measuring electric charge or electrical potential difference. There are many different types, ranging from historical handmade mechanical instruments to high-precision electronic devices. Modern electrometers based on vacuum tube or solid-state technology can be used to make voltage and charge measurements with very low leakage currents, down to 1 femtoampere. A simpler but related instrument, the electroscope, works on similar principles but only indicates the relative magnitudes of voltages or charges. Historical electrometers Gold-leaf electroscope The gold-leaf electroscope was one of the instruments used to indicate electric charge. It is still used for science demonstrations but has been superseded in most applications by electronic measuring instruments. The instrument consists of two thin leaves of gold foil suspended from an electrode. When the electrode is charged by induction or by contact, the leaves acquire simi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evaporative Light Scattering Detector (ELSD)
An evaporative light scattering detector (ELSD) is a detector used in conjunction with high-performance liquid chromatography (HPLC), Ultra high-performance liquid chromatography (UHPLC), Purification liquid chromatography such as flash or preparative chromatography, countercurrent or centrifugal partition chromatographies and Supercritical Fluid chromatography (SFC). It is commonly used for analysis of compounds where UV detection might be a restriction and therefore used where compounds do not efficiently absorb UV radiation, such as sugars, antivirals, antibiotics, fatty acids, lipids, oils, phospholipids, polymers, surfactants, terpenoids and triglycerides. ELSDs is related to the charged aerosol detector (CAD) and like the CAD, falls under the category of destructive detectors. An evaporative light scattering detector (ELSD) is able to detect all compound which are less volatile than the mobile phase, i.e. non volatile and semi-volatile compounds. Principles of operation ELS ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromatography Detector
A chromatography detector is a device used in gas chromatography (GC) or liquid chromatography (LC) to detect components of the mixture being eluted off the chromatography column. There are two general types of detectors: destructive and non-destructive. The destructive detectors perform continuous transformation of the column effluent (burning, evaporation or mixing with reagents) with subsequent measurement of some physical property of the resulting material (plasma, aerosol or reaction mixture). The non-destructive detectors are directly measuring some property of the column eluent (for example UV absorption) and thus affords greater analyte recovery. Destructive detectors In liquid chromatography: * Charged aerosol detector (CAD) * Evaporative light scattering detector (ELSD) In gas chromatography: * Flame ionization detector (FID) * Flame photometric detector (FPD) * Nitrogen Phosphorus Detector (NPD) * Atomic-emission detector (AED) In all types of chromatography: * Ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pittcon Editors' Awards
Pittcon Editors’ Awards honoured the best new products on show at the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, or Pittcon, for 20 years from 1996 having been established by Dr Gordon Wilkinson, managing editor of ''Analytical Instrument Industry Report'' (later ''Instrumenta''). On 8 March 2015, the event returned to the Morial Convention Center in New Orleans and this was the last occasion when the awards were presented. The independent awards, which represented the results of an informal poll of leading editors, had become an important feature of the world's largest trade show for the laboratory equipment industry. Pittcon organisers and media center supported the scheme and provided details and photographs on the exhibition's Press and Media Information page. In 2016 the group of editors and journalists that formed the core of the judging panel reluctantly decided to discontinue the awards program citing gradually dwindling support from ever-bus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evaporative Light Scattering Detector (ELSD)
An evaporative light scattering detector (ELSD) is a detector used in conjunction with high-performance liquid chromatography (HPLC), Ultra high-performance liquid chromatography (UHPLC), Purification liquid chromatography such as flash or preparative chromatography, countercurrent or centrifugal partition chromatographies and Supercritical Fluid chromatography (SFC). It is commonly used for analysis of compounds where UV detection might be a restriction and therefore used where compounds do not efficiently absorb UV radiation, such as sugars, antivirals, antibiotics, fatty acids, lipids, oils, phospholipids, polymers, surfactants, terpenoids and triglycerides. ELSDs is related to the charged aerosol detector (CAD) and like the CAD, falls under the category of destructive detectors. An evaporative light scattering detector (ELSD) is able to detect all compound which are less volatile than the mobile phase, i.e. non volatile and semi-volatile compounds. Principles of operation ELS ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
