Chaetomium Perlucidum
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Chaetomium Perlucidum
''Chaetomium perlucidum'' is a neurotropic dematiaceous (melanated cell wall) fungus that is naturally found in the soil, including in agricultural soil, and in the stems of dead plants. The fungus can also be found on the feathers of birds, manure, seeds, and even paper. It is able to thrive at temperatures of . The fungus is an invasive opportunist to humans that can cause diseases such as onychomycosis (fungus on nails), otolaryngologic (head and neck) or respiratory inflammations (like sinusitis, pneumonia, and empyema), and brain necrosis. History It was first formally recorded in 1956 in Ukraine by K. S. Sergeeva. Morphology ''Chaetomium perlucidum'' is pigmented and dark in colour, appearing hairy and wooly, with a growth rate of 4-5 mm/day. Perithecia (fruiting body) ''Chaetomium perlucidum'''s fruiting bodies become fully mature in 13-16 days. The fruiting body's structural width is 90-200 μm, with an ostiolar pore (open pore) width of 30-50 μm. Seta ...
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Klavdia Spiridonovna Sergeeva
Klavdia ( el, Κλαυδιά; tr, Klavya or ) is a village in the Larnaca District of Cyprus, located west of Larnaca. Prior to 1974, the village was inhabited solely by Turkish Cypriots Turkish Cypriots or Cypriot Turks ( tr, Kıbrıs Türkleri or ''Kıbrıslı Türkler''; el, Τουρκοκύπριοι, Tourkokýprioi) are ethnic Turks originating from Cyprus. Following the Ottoman conquest of the island in 1571, about 30,00 .... References Communities in Larnaca District Turkish Cypriot villages depopulated after the 1974 Turkish invasion of Cyprus {{cyprus-geo-stub ...
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Stearic Acid
Stearic acid ( , ) is a saturated fatty acid with an 18-carbon chain. The IUPAC name is octadecanoic acid. It is a waxy solid and its chemical formula is C17H35CO2H. Its name comes from the Greek word στέαρ "''stéar''", which means tallow. The salts and esters of stearic acid are called stearates. As its ester, stearic acid is one of the most common saturated fatty acids found in nature following palmitic acid.Gunstone, F. D., John L. Harwood, and Albert J. Dijkstra "The Lipid Handbook with Cd-Rom. 3rd ed. Boca Raton: CRC Press, 2007. , The triglyceride derived from three molecules of stearic acid is called stearin. Occurrence and production Stearic acid is more abundant in animal fat (up to 30%) than in vegetable fat (typically <5%). The important exceptions are the foods (34%) and
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Lobectomy
Lobectomy means ''surgical excision of a lobe''. This may refer to a lobe of the lung (also simply called a lobectomy), a lobe of the thyroid (hemithyroidectomy), a lobe of the brain (as in anterior temporal lobectomy), or a lobe of the liver (hepatectomy). __TOC__ Lung lobectomy A lobectomy of the lung is performed in early-stage non-small cell lung cancer patients. It is not performed on patients that have lung cancer that has spread to other parts of the body. Tumor size, type, and location are major factors as to whether a lobectomy is performed. This can be due to cancer or smoking. Lung lobectomies are performed on patients as young as eleven or twelve who have no cancer or smoking history, but have conditions from birth or early childhood that necessitate the operation. Such patients will have reduced lung capacity which tends to limit their range of activities through life. They often need to use inhalers on a daily basis, and are often classified as being asthma ...
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Acute Inflammation
Inflammation (from la, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out necrotic cells and tissues damaged from the original insult and the inflammatory process, and initiate tissue repair. The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin ''calor'', ''dolor'', ''rubor'', ''tumor'', and ''functio laesa''). Inflammation is a generic response, and therefore it is considered as a mechanism of innate immunity, as compared to adaptive immunity, which is specific for each pathogen. Too little inflammation could lead to progressive tissue destruction by the harmful stimulus (e.g. bacteria) and compromise the survival of the organism. In contrast, too much inflammation, in the ...
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Amphotericin B
Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. For certain infections it is given with flucytosine. It is typically given intravenously (injection into a vein). Common side effects include a reaction with fever, chills, and headaches soon after the medication is given, as well as kidney problems. Allergic symptoms including anaphylaxis may occur. Other serious side effects include low blood potassium and myocarditis (inflammation of the heart). It appears to be relatively safe in pregnancy. There is a lipid formulation that has a lower risk of side effects. It is in the polyene class of medications and works in part by interfering with the cell membrane of the fungus. Amphotericin B was isolated from '' Streptomyces nodosus'' in 1955 at the Squibb For Medical Research Institute from c ...
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Phaeohyphomycosis
Phaeohyphomycosis is a diverse group of fungal infections, caused by dematiaceous fungi whose morphologic characteristics in tissue include hyphae, yeast-like cells, or a combination of these. It can be associated an array of melanistic filamentous fungi including ''Alternaria'' species'','' ''Exophiala jeanselmei,'' and ''Rhinocladiella mackenziei''. The term "phaeohyphomycosis" was introduced to determine infections caused by dematiaceous (pigmented) filamentous fungi which contain melanin in their cell walls. Phaeohyphomycosis is an uncommon infection, but the number of cases reported has been increasing in recent years. Fungal melanin is thought to be a virulence factor. The outcome of antifungal treatment is poor, and mortality is almost 80%.Sanjay G.R., J.E. Patterson, D.DA. Sutton, R.Pullen, and M.G. Rinaldi. 2002. Disseminated phaeohyphomycosis:review of an emerging Mycosis. Clinical Infectious Disease 34:467-476. Phaeohyphomycosis has been attributed to more than 100 s ...
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Linoleic Acid
Linoleic acid (LA) is an organic compound with the formula COOH(CH2)7CH=CHCH2CH=CH(CH2)4CH3. Both alkene groups are cis-trans isomerism, ''cis''. It is a fatty acid sometimes denoted 18:2 (n-6) or 18:2 ''cis''-9,12. A linoleate is a salt (chemistry), salt or ester of this acid. Linoleic acid is a polyunsaturated fatty acid, polyunsaturated omega-6 fatty acid. It is a colorless liquid that is virtually insoluble in water but soluble in many organic solvents. It typically occurs in nature as a triglyceride (ester of glycerol, glycerin) rather than as a free fatty acid. It is one of two essential fatty acids for humans, who must obtain it through their diet, and the most essential, because the body uses it as a base to make the others. The word "linoleic" derives from the Latin ''linum'' "flax" + ''oleum'' "oil", reflecting the fact that it was first isolated from linseed oil. History In 1844, F. Sacc, working at the laboratory of Justus von Liebig, isolated linoleic acid from l ...
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Oleic Acid
Oleic acid is a fatty acid that occurs naturally in various animal and vegetable fats and oils. It is an odorless, colorless oil, although commercial samples may be yellowish. In chemical terms, oleic acid is classified as a monounsaturated omega-9 fatty acid, abbreviated with a lipid number of 18:1 ''cis''-9, and a main product of Δ9 desaturase. It has the formula CH3(CH2)7CH=CH(CH2)7COOH. The name derives from the Latin word ''oleum'', which means oil. It is the most common fatty acid in nature. The salts and esters of oleic acid are called oleates. Occurrence Fatty acids (or their salts) often do not occur as such in biological systems. Instead fatty acids such as oleic acid occur as their esters, commonly triglycerides, which are the greasy materials in many natural oils. Oleic acid is the most common monounsaturated fatty acid in nature. It is found in fats (triglycerides), the phospholipids that make membranes, cholesterol esters, and wax esters. Triglycerides of oleic ...
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Palmitoleic Acid
Palmitoleic acid, or (9''Z'')-hexadec-9-enoic acid, is an omega-7 monounsaturated fatty acid (16:1n-7) with the formula CH3(CH2)5CH=CH(CH2)7COOH that is a common constituent of the glycerides of human adipose tissue. It is present in all tissues but, in general, found in higher concentrations in the liver. It is biosynthesized from palmitic acid by the action of the enzyme Stearoyl-CoA desaturase-1. Animal and cell culture studies indicate that palmitoleic acid is anti-inflammatory, and improves insulin sensitivity in liver and skeletal muscles, but more studies are required to establish its actions in humans. Many of the effects of palmitoleic acid are due to its activation of PPAR-alpha. Dietary sources Palmitoleic acid can be abbreviated as 16:1∆9. Dietary sources of palmitoleic acid include breast milk, a variety of animal fats, vegetable oils, and marine oils. Macadamia oil (''Macadamia integrifolia'') and sea buckthorn oil (''Hippophae rhamnoides ''Hippophae rha ...
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Opportunism
Opportunism is the practice of taking advantage of circumstances – with little regard for principles or with what the consequences are for others. Opportunist actions are expedient actions guided primarily by self-interested motives. The term can be applied to individual humans and living organisms, groups, organizations, styles, behaviors, and trends. Opportunism or "opportunistic behaviour" is an important concept in such fields of study as biology, transaction cost economics, game theory, ethics, psychology, sociology and politics. Definitions Opportunism is the conscious policy and practice of taking selfish advantage of circumstances. Although in many societies opportunism often has a strong negative moral connotation, it may also be defined more neutrally as putting self-interest before other interests when there is an opportunity to do so, or flexibly adapting to changing circumstances to maximize self-interest (though usually in a way that negates some principle prev ...
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Palmitic Acid
Palmitic acid (hexadecanoic acid in IUPAC nomenclature) is a fatty acid with a 16-carbon chain. It is the most common saturated fatty acid found in animals, plants and microorganisms.Gunstone, F. D., John L. Harwood, and Albert J. Dijkstra. The Lipid Handbook, 3rd ed. Boca Raton: CRC Press, 2007. , Its chemical formula is CH3(CH2)14COOH, and its C:D (the total number of carbon atoms to the number of carbon-carbon double-bonds) is 16:0. It is a major component of the oil from the fruit of oil palms ( palm oil), making up to 44% of total fats. Meats, cheeses, butter, and other dairy products also contain palmitic acid, amounting to 50–60% of total fats. Palmitates are the salts and esters of palmitic acid. The palmitate anion is the observed form of palmitic acid at physiologic pH (7.4). Occurrence and production Palmitic acid was discovered by Edmond Frémy in 1840, in saponified palm oil. This remains the primary industrial route for its production, with the triglycerides (fa ...
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Pentadecanoic Acid
Pentadecylic acid, also known as pentadecanoic acid or C15:0 is an odd-chain saturated fatty acid. It is a colorless solid. A laboratory preparation involves permanganate oxidation of 1-hexadecene (CH3(CH2)13CH=CH2). Pentadecylic acid is found primarily in dairy fat, as well as in ruminant meat and some types of fish and plants. Its molecular formula is CH3(CH2)13CO2H. It is one of the most common odd-chain fatty acids, although it is rare in nature, comprising 1.2% of milk fat from cows. The butterfat in cows milk is its major dietary source and it is used as a marker for butterfat consumption. Pentadecylic acid also occurs in hydrogenated mutton fat. Higher circulating concentrations of C15:0 have been associated with a lower risk of developing type 2 diabetes and cardiovascular disease. Higher C15:0 concentrations have also been linked to a lower risk of chronic inflammation, adiposity, metabolic syndrome, nonalcoholic steatohepatitis, chronic obstructive pulmonary disease, ...
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