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Cephalotaxus Harringtonii
''Cephalotaxus harringtonia'', commonly known as Japanese plum-yew, Harrington's cephalotaxus, or cowtail pine, is a coniferous bush or small tree in the family Taxaceae. It is native to Japan, but is occasionally utilised in western gardens and several cultivars exist for these purposes. Japanese plum yew has been in cultivation in Europe since 1829, and many modern horticulturists are familiar with this Japanese species, named in honor of Charles Stanhope, 4th Earl of Harrington, one of the first to grow the plant in a European garden, at Elvaston. Description New shoots of ''C. harringtonii'' remain green for three years after forming and have ribs at the leaf bases. The buds are green in colour, globular in shape and very small at only 1 mm in length. There is one rank of leaves present on either side of the shoot, and these rise up above it and curve slightly inwards, forming a narrow V-shape somewhat akin to a dove's wings. The ranks are often vertical, but can be more ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Botanical Garden In Berlin
The Berlin Botanic Garden and Botanical Museum (german: Botanischer Garten und Botanisches Museum Berlin) is a botanical garden in the locality of the borough of , Berlin, Germany. Constructed between 1897 and 1910 under the guidance of architect Adolf Engler, it has an area of and around 22,000 different plant species. The garden is part of the Free University of Berlin. The most well-known part of the garden is the Great Pavilion (), and among its many tropical plants, it hosts giant bamboo. The garden complex consists of several buildings, including glass-houses with a total area of . These include the glass Cactus Pavilion and the glass Pavilion Victoria; the latter features a collection of orchids, carnivorous plants and the giant white water lily ''Victoria amazonica'' (). The open-air areas are sorted by geographical origin and encompass about . The arboretum is about . The Botanical Museum (), the (B) and a large scientific library are attached to the garden. The i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cephalotaxus Koreana
''Cephalotaxus koreana'', commonly called the Korean plum yew, is a coniferous shrub or small tree in the family Taxaceae. It is native to Korea, Japan and northeast China. Some botanists consider it synonymous with '' C. harringtonii''. ''Cephalotaxus koreana'' contains catechin-7-O-glucoside Catechin-7-''O''-glucoside is a flavan-3-ol glycoside formed from catechin. Natural occurrences Catechin-7-''O''-glucoside can be isolated from the hemolymph of the European pine sawfly ('' Neodiprion sertifer''). It also occurs in relatively ....Inhibitors of Osteoclast Differentiation from Cephalotaxus koreana. Kee Dong Yoon, Doc Gyun Jeong, Yun Ha Hwang, Jei Man Ryu and Jinwoong Kim, J. Nat. Prod., 2007, 70, pages 2029–2032, References {{Taxonbar, from=Q3445020 Flora of China Flora of Japan Trees of Korea Flora of Asia koreana Taxa named by Takenoshin Nakai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cephalotaxus
''Cephalotaxus'', commonly called plum yew or cowtail pine, is a genus of conifers comprising 11 species, treated in either the Cephalotaxaceae, or in the Taxaceae when that family is considered in a broad sense. The genus is endemic to eastern Asia, though fossil evidence shows it had a wider Northern Hemisphere distribution in the past. The species are evergreen shrubs and small trees reaching (rarely to ) tall. Taxonomy Molecular studies place ''Cephalotaxus'' as the most basal member of the Taxaceae, having a very ancient divergence from them during the late Triassic. Description The leaves are spirally arranged on the shoots, but twisted at the base to lie in two flat ranks (except on erect leading shoots); they are linear, long and broad, soft in texture, with a blunt tip; this helps distinguish them from the related genus ''Torreya'', which has spine-tipped leaves. The species can be either monoecious or dioecious; when monoecious, the male and female cones are often ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leukemia
Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ''leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia— acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myeloi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Omacetaxine
Omacetaxine mepesuccinate (INN, trade names Synribo ), formerly named as homoharringtonine or HHT, is a pharmaceutical drug substance that is indicated for treatment of chronic myeloid leukemia (CML). HHT is a natural plant alkaloid derived from ''Cephalotaxus fortunei''. HHT and related compound esters of cephalotaxine were described first in 1970, and were the subject of intensive research efforts by Chinese investigators to clarify their role as anticancer and antileukemic agents from the 1970s until the present. It was approved by the US FDA in October 2012 for the treatment of adult patients with CML with resistance and/or intolerance to two or more tyrosine kinase inhibitors (TKIs). Medical uses Omacetaxine/homoharringtonine is indicated for use as a treatment for patients with chronic myeloid leukaemia who are resistant or intolerant of tyrosine kinase inhibitors. In June 2009, results of a long-term open label Phase II study were published, which investigated the use o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and Northern Ireland. The United Kingdom includes the island of Great Britain, the north-eastern part of the island of Ireland, and many smaller islands within the British Isles. Northern Ireland shares a land border with the Republic of Ireland; otherwise, the United Kingdom is surrounded by the Atlantic Ocean, the North Sea, the English Channel, the Celtic Sea and the Irish Sea. The total area of the United Kingdom is , with an estimated 2020 population of more than 67 million people. The United Kingdom has evolved from a series of annexations, unions and separations of constituent countries over several hundred years. The Treaty of Union between the Kingdom of England (which included Wales, annexed in 1542) and the Kingdom of Scotland in 170 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Honshū
, historically called , is the largest and most populous island of Japan. It is located south of Hokkaidō across the Tsugaru Strait, north of Shikoku across the Inland Sea, and northeast of Kyūshū across the Kanmon Straits. The island separates the Sea of Japan, which lies to its north and west, from the North Pacific Ocean to the south and east. It is the seventh-largest island in the world, and the second-most populous after the Indonesian island of Java. Honshu had a population of 104 million , constituting 81.3% of the entire population of Japan, and is mostly concentrated in the coastal areas and plains. Approximately 30% of the total population resides in the Greater Tokyo Area on the Kantō Plain. As the historical center of Japanese cultural and political power, the island includes several past Japanese capitals, including Kyōto, Nara and Kamakura. Much of the island's southern shore forms part of the Taiheiyō Belt, a megalopolis that spans several of the Japanese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hiroshima Prefecture
is a Prefectures of Japan, prefecture of Japan located in the Chūgoku region of Honshu. Hiroshima Prefecture has a population of 2,811,410 (1 June 2019) and has a geographic area of 8,479 km² (3,274 sq mi). Hiroshima Prefecture borders Okayama Prefecture to the east, Tottori Prefecture to the northeast, Shimane Prefecture to the north, and Yamaguchi Prefecture to the southwest. Hiroshima is the capital and largest city of Hiroshima Prefecture, and the largest city in the Chūgoku region, with other major cities including Fukuyama, Hiroshima, Fukuyama, Kure, Hiroshima, Kure, and Higashihiroshima. Hiroshima Prefecture is located on the Seto Inland Sea across from the island of Shikoku, and is bounded to the north by the Chūgoku Mountains. Hiroshima Prefecture is one of the three prefectures of Japan with more than one UNESCO World Heritage Site. History The area around Hiroshima was formerly divided into Bingo Province and Aki Province. This location has been a center of tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nagasaki Prefecture
is a Prefectures of Japan, prefecture of Japan located on the island of Kyūshū. Nagasaki Prefecture has a population of 1,314,078 (1 June 2020) and has a geographic area of 4,130 Square kilometre, km2 (1,594 sq mi). Nagasaki Prefecture borders Saga Prefecture to the northeast. Nagasaki is the capital and largest city of Nagasaki Prefecture, with other major cities including Sasebo, Nagasaki, Sasebo, Isahaya, Nagasaki, Isahaya, and Ōmura, Nagasaki, Ōmura. Nagasaki Prefecture is located in western Kyūshū with a territory consisting of many mainland peninsulas centered around Ōmura Bay, as well as islands and archipelagos including Tsushima Island, Tsushima and Iki Island, Iki in the Korea Strait and the Gotō Islands in the East China Sea. Nagasaki Prefecture is known for its century-long Nanban trade, trading history with the Europeans and as the sole place of direct trade and exchange between Japan and the outside world during the ''Sakoku'' period. Nagasaki Prefecture is h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Awa Province (Chiba)
was a province of Japan in the area of modern Chiba Prefecture. Nussbaum, Louis-Frédéric. (2005). "''Awa no Kuni''" in . It lies on the tip of the Bōsō Peninsula (房総半島), whose name takes its first ''kanji'' from the name of Awa Province and its second from Kazusa and Shimōsa Provinces. Its abbreviated form name was or . Awa Province in Shikoku phonetically has the same name, but is written with different ''kanji'' (阿波国). Awa is classified as one of the provinces of the Tōkaidō. Under the ''Engishiki'' classification system, Awa was ranked as a "middle country" (中国) and a "far country" (遠国). History Awa was originally one of four districts of Kazusa Province. It was well-known to the Imperial Court in Nara period Japan for its bountiful seafoods, and is mentioned in Nara period records as having supplied fish to the Court as early as the reign of the semi-legendary Emperor Keikō. On May 2, 718 the district of Awa was elevated into status to a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Awa District, Chiba
is a district located in Chiba Prefecture, Japan. As of August 2010, the district had an estimated population of 8,992 and a density of 198 persons per km2. Its total area was . Awa District at present consists only of the town of Kyonan History Awa District was one of the ancient districts of Kazusa Province, and originally covered all of the southern end of Bōsō Peninsula. In 718, it was separated from Kazusa to become the separate province of Awa, which existed to the Meiji Restoration of 1868. In the cadastral reforms of the early Meiji period, Awa Province was divided into four modern districts in 1868: , , and (formerly called Heguri). At the time of its formation, Awa District consisted of 93 hamlets, divided evenly between Tateyama Domain and Nagao Domain. These were consolidated into two towns (Tateyama and Hōjō, which merged with Tateyama in 1993) and nine villages. In 1897, three districts of Asai, Hei and Nagasa were absorbed into Awa District, at which time Aw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chiba Prefecture
is a prefecture of Japan located in the Kantō region of Honshu. Chiba Prefecture has a population of 6,278,060 (1 June 2019) and has a geographic area of . Chiba Prefecture borders Ibaraki Prefecture to the north, Saitama Prefecture to the northwest, and Tokyo to the west. Chiba is the capital and largest city of Chiba Prefecture, with other major cities including Funabashi, Matsudo, Ichikawa and Kashiwa. Chiba Prefecture is located on Japan's eastern Pacific coast to the east of Tokyo, and is part of the Greater Tokyo Area, the most populous metropolitan area in the world. Chiba Prefecture largely consists of the Bōsō Peninsula, which encloses the eastern side of Tokyo Bay and separates it from Kanagawa Prefecture. Chiba Prefecture is home to Narita International Airport, the Tokyo Disney Resort, and the Keiyō Industrial Zone. Etymology The name of Chiba Prefecture in Japanese is formed from two kanji characters. The first, , means "thousand" and the second, means " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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