Cataracts (canine)

	Cataracts (canine) Canine cataracts are a prevalent cause of visual loss in dogs, frequently resulting in blindness. Cataracts typically occur when proteins break down in the lens of a dog's eye and clump together, obstructing the passage of light. There are several reasons cataracts may occur in dogs, such as heredity, trauma, aging, diabetes, glaucoma, and progressive retinal atrophy. Causes Cataracts can be genetic, existing in breeds who are predisposed to developing them. Canine diabetes is another common cause of canine cataracts, due to the increased concentration of glucose in the lens, which swells the lens. A third prevalent cause of canine cataracts is developmental, in which certain embryological conditions, like toxins or infections, cause cataracts present at birth. Two different mutations in the HSF4 Heat shock factor protein 4 is a protein that in humans is encoded by the ''HSF4'' gene. Heat-shock transcription factors (HSFs) activate heat-shock response genes under condition ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Cão Com Catarata Parte Cao or CAO may refer to: Mythology Cao (bull), a legendary bull in Meitei mythology Companies or organizations Air China Cargo, ICAO airline designator CAO * CA Oradea, Romanian football club * CA Osasuna, Spanish football club * Canadian Association of Orthodontists * Central Allocation Office, cross border electricity transmission capacity auction office * Central Applications Office, Irish organisation that oversees college applications Civil Aviation Office of Poland Iran Civil Aviation Organization Office of the Compliance Advisor/Ombudsman Job titles Chief Academic Officer of a University, often titled the Provost Chief accounting officer of a company Chief administrative officer of a company Chief analytics officer of a company Compliance Advisor/Ombudsman, an independent office that reviews complaints Names * Cao (Chinese surname) (曹) * Cao (Vietnamese surname) People Cao (footballer, born 1968), Portuguese footballer Cao Cao (died 220), founder of Cao ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Cataract A cataract is a cloudy area in the lens of the eye that leads to a decrease in vision. Cataracts often develop slowly and can affect one or both eyes. Symptoms may include faded colors, blurry or double vision, halos around light, trouble with bright lights, and trouble seeing at night. This may result in trouble driving, reading, or recognizing faces. Poor vision caused by cataracts may also result in an increased risk of falling and depression. Cataracts cause 51% of all cases of blindness and 33% of visual impairment worldwide. Cataracts are most commonly due to aging but may also occur due to trauma or radiation exposure, be present from birth, or occur following eye surgery for other problems. Risk factors include diabetes, longstanding use of corticosteroid medication, smoking tobacco, prolonged exposure to sunlight, and alcohol. The underlying mechanism involves accumulation of clumps of protein or yellow-brown pigment in the lens that reduces transmission of li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Diabetes In Dogs Diabetes mellitus is a disease in which the beta cells of the endocrine pancreas either stop producing insulin or can no longer produce it in enough quantity for the body's needs. The disease can affect humans as well as animals such as dogs. The condition is treatable and need not shorten the animal's life span or interfere with quality of life. If left untreated, the condition can lead to cataracts, increasing weakness in the legs (neuropathy), malnutrition, ketoacidosis, dehydration, and death. Diabetes mainly affects middle-age and older dogs, but there are juvenile cases. (PDF) The typical canine diabetes patient is middle-age, female, and overweight at diagnosis. The number of dogs diagnosed with diabetes mellitus has increased three-fold in thirty years. In survival rates from almost the same time, only 50% survived the first 60 days after diagnosis and went on to be successfully treated at home. Currently, diabetic dogs receiving treatment have the same expected lifespan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Glaucoma Glaucoma is a group of eye diseases that result in damage to the optic nerve (or retina) and cause vision loss. The most common type is open-angle (wide angle, chronic simple) glaucoma, in which the drainage angle for fluid within the eye remains open, with less common types including closed-angle (narrow angle, acute congestive) glaucoma and normal-tension glaucoma. Open-angle glaucoma develops slowly over time and there is no pain. Peripheral vision may begin to decrease, followed by central vision, resulting in blindness if not treated. Closed-angle glaucoma can present gradually or suddenly. The sudden presentation may involve severe eye pain, blurred vision, mid-dilated pupil, redness of the eye, and nausea. Vision loss from glaucoma, once it has occurred, is permanent. Eyes affected by glaucoma are referred to as being glaucomatous. Risk factors for glaucoma include increasing age, high pressure in the eye, a family history of glaucoma, and use of steroid medication. F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Progressive Retinal Atrophy Progressive retinal atrophy (PRA) is a group of genetic diseases seen in certain breeds of dogs and, more rarely, cats. Similar to retinitis pigmentosa in humans, it is characterized by the bilateral degeneration of the retina, causing progressive vision loss culminating in blindness. The condition in nearly all breeds is inherited as an autosomal recessive trait, with the exception of the Siberian Husky (inherited as an X chromosome linked trait) and the Bullmastiff (inherited as an autosomal dominant trait). There is no treatment. Types of PRA In general, PRAs are characterised by initial loss of rod photoreceptor cell function followed by that of the cones and for this reason night blindness is the first significant clinical sign for most dogs affected with PRA. As other retinal disorders, PRA can be divided into either dysplastic disease, where the cells develop abnormally, and degenerative, where the cells develop normally but then degenerate during the dog's lifetime. Ge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	HSF4 Heat shock factor protein 4 is a protein that in humans is encoded by the ''HSF4'' gene. Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described. See also * Heat shock factor In molecular biology, heat shock factors (HSF), are the transcription factors that regulate the expression of the heat shock proteins. A typical example is the heat shock factor of ''Drosophila melanogaster''. Function Heat shock factors (H ... References Further reading * * * * * * * * * * External links * Transcription factors {{gene-16-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]