|
Casimir Funk
Kazimierz Funk (; February 23, 1884 – November 19, 1967), commonly anglicized as Casimir Funk, was a Polish-American biochemist generally credited with being among the first to formulate (in 1912) the concept of vitamins, which he called "vital amines" or "vitamines". Achievements After reading an article by the Dutchman Christiaan Eijkman that indicated that persons who ate brown rice were less vulnerable to beri-beri than those who ate only the fully milled product, Funk tried to isolate the substance responsible, and he succeeded. Because that substance contained an amine group, he called it "vitamine". It was later to be known as vitamin B3 (niacin), though he thought that it would be thiamine (vitamin B1) and described it as "anti-beri-beri-factor". In 1911 he published his first paper in English, on dihydroxyphenylalanine. Funk was sure that more than one substance like Vitamin B1 existed, and in his 1912 article for the Journal of State Medicine, he proposed the existenc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thiamine
Thiamine, also known as thiamin and vitamin B1, is a vitamin, an essential micronutrient, that cannot be made in the body. It is found in food and commercially synthesized to be a dietary supplement or medication. Phosphorylated forms of thiamine are required for some metabolic reactions, including the breakdown of glucose and amino acids. Food sources of thiamine include whole grains, legumes, and some meats and fish. Grain processing removes much of the vitamin content, so in many countries cereals and flours are enriched with thiamine. Supplements and medications are available to treat and prevent thiamine deficiency and disorders that result from it include beriberi and Wernicke encephalopathy. They are also used to treat maple syrup urine disease and Leigh syndrome. Supplements and medications are typically taken by mouth, but may also be given by intravenous or intramuscular injection. Thiamine supplements are generally well tolerated. Allergic reactions, including ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beriberi
Thiamine deficiency is a medical condition of low levels of thiamine (Vitamin B1). A severe and chronic form is known as beriberi. The two main types in adults are wet beriberi and dry beriberi. Wet beriberi affects the cardiovascular system, resulting in a fast heart rate, shortness of breath, and leg swelling. Dry beriberi affects the nervous system, resulting in numbness of the hands and feet, confusion, trouble moving the legs, and pain. A form with loss of appetite and constipation may also occur. Another type, acute beriberi, found mostly in babies, presents with loss of appetite, vomiting, lactic acidosis, changes in heart rate, and enlargement of the heart. Risk factors include a diet of mostly white rice, alcoholism, dialysis, chronic diarrhea, and taking high doses of diuretics. In rare cases, it may be due to a genetic condition that results in difficulties absorbing thiamine found in food. Wernicke encephalopathy and Korsakoff syndrome are forms of dry beriberi. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hilary Koprowski
Hilary Koprowski (5 December 191611 April 2013) was a Polish virologist and immunologist active in the United States who demonstrated the world's first effective live polio vaccine. He authored or co-authored over 875 scientific papers and co-edited several scientific journals. Koprowski received many academic honors and national decorations, including the Belgian Order of the Lion, the French Order of Merit and Legion of Honour, Finland's Order of the Lion, and the Order of Merit of the Republic of Poland. Koprowski was the target of accusations in the press related to the " oral polio vaccine AIDS hypothesis", which posited that the AIDS pandemic originated from live polio vaccines such as Koprowski's. This allegation has long been refuted by evidence showing that the HIV-1 virus was introduced to humans before his polio-vaccine trials were conducted in Africa. The case was settled out of court with a formal apology from ''Rolling Stone'' magazine. Life Hilary Koprowski ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aleksander Wolszczan
Aleksander Wolszczan (born 29 April 1946) is a Polish astronomer. He is the co-discoverer of the first confirmed extrasolar planets and pulsar planets. Early life and education Wolszczan was born on 29 April 1946 in Szczecinek located in present-day West Pomeranian Voivodeship, Poland; in the 1950s his family moved to Szczecin. His father Jerzy Wolszczan taught economics at former Szczecin Polytechnic (currently West Pomeranian University of Technology) and his mother, Zofia, worked for the Polish Writers' Union. His early interest in astronomy was inspired by his father who told him stories and myths connected with stellar constellations. As a seven-year-old he already learned the basics of astronomy. He observed the night sky using a small telescope he constructed himself. He graduated from Stefan Czarniecki VI High School in Szczecin. Scientific career Wolszczan sat for an M.Sc. in 1969 and a Ph.D. in 1975 at the Nicolaus Copernicus University in Toruń, Poland. Between ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roald Hoffmann
Roald Hoffmann (born Roald Safran; July 18, 1937) is a Polish Americans, Polish-American theoretical chemistry, theoretical chemist who won the 1981 Nobel Prize in Chemistry. He has also published plays and poetry. He is the Frank H. T. Rhodes Professor of Humane Letters, Emeritus, at Cornell University, in Ithaca, New York. Early life Escape from the Holocaust Hoffmann was born in Złoczów, Second Polish Republic (now Zolochiv, Ukraine), to a Polish-Jewish family, and was named in honor of the Norway, Norwegian explorer Roald Amundsen. His parents were Clara (Rosen), a teacher, and Hillel Safran, a civil engineer. After Germany invaded Poland and occupied the town, his family was placed in a labor camp where his father, who was familiar with much of the local infrastructure, was a valued prisoner. As the situation grew more dangerous, with prisoners being transferred to extermination camps, the family bribed guards to allow an escape. They arranged with a Ukrainian neighbor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polish Institute Of Arts And Sciences Of America
The Polish Institute of Arts and Sciences of America (PIASA) is a Polish-American scholarly institution headquartered in Manhattan (New York City), at 208 East 30th Street. History The Institute was founded during the height of World War II, in 1942, by Polish scholars, including historian Stanisław Kot, anthropologist Bronisław Malinowski, poet Jan Lechoń, and historians Oskar Halecki and Rafał Taubenschlag, to continue the work and tradition of the prewar Polish Academy of Learning (''Polska Akademia Umiejętności''), headquartered in Kraków, Poland, which had been destroyed by Nazi Germany in 1939. Since World War II, the Institute has continued its work of promoting Polish and Polish-American excellence in learning, and of advancing the knowledge of Polish history and culture in the English-speaking world. Since Poland's resumption of a more complete sovereignty following the collapse of communism in central and eastern Europe, the Polish Institute has established coll ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neoplasm
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peptic Ulcer
Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. The most common symptoms of a duodenal ulcer are waking at night with upper abdominal pain and upper abdominal pain that improves with eating. With a gastric ulcer, the pain may worsen with eating. The pain is often described as a burning or dull ache. Other symptoms include belching, vomiting, weight loss, or poor appetite. About a third of older people have no symptoms. Complications may include bleeding, perforation, and blockage of the stomach. Bleeding occurs in as many as 15% of cases. Common causes include the bacteria ''Helicobacter pylori'' and non-steroidal anti-inflammatory drugs (NSAIDs). Other, less common causes include tobacco smoking, stress as a result of other serious health conditions, Behçet's di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diabetes
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to lo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hormone
A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are required for the correct development of animals, plants and fungi. Due to the broad definition of a hormone (as a signaling molecule that exerts its effects far from its site of production), numerous kinds of molecules can be classified as hormones. Among the substances that can be considered hormones, are eicosanoids (e.g. prostaglandins and thromboxanes), steroids (e.g. oestrogen and brassinosteroid), amino acid derivatives (e.g. epinephrine and auxin), protein or peptides (e.g. insulin and CLE peptides), and gases (e.g. ethylene and nitric oxide). Hormones are used to communicate between organs and tissues. In vertebrates, hormones are responsible for regulating a variety of physiological processes and behavioral activities such as diges ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coeliac Disease
Coeliac disease (British English) or celiac disease (American English) is a long-term autoimmune disorder, primarily affecting the small intestine, where individuals develop intolerance to gluten, present in foods such as wheat, rye and barley. Classic symptoms include gastrointestinal problems such as chronic diarrhoea, abdominal distention, malabsorption, loss of appetite, and among children failure to grow normally. This often begins between six months and two years of age. Non-classic symptoms are more common, especially in people older than two years. There may be mild or absent gastrointestinal symptoms, a wide number of symptoms involving any part of the body, or no obvious symptoms. Coeliac disease was first described in childhood; however, it may develop at any age. It is associated with other autoimmune diseases, such as Type 1 diabetes mellitus and Hashimoto's thyroiditis, among others. Coeliac disease is caused by a reaction to gluten, a group of various prote ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
