Carol Orzel
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Carol Orzel
Carol Orzel (April 20, 1959 – February 2018) was an American woman with fibrodysplasia ossificans progressiva (FOP). She advocated for research into FOP and was an activist for disability rights. Before her death, she requested that her skeleton be displayed in the Mütter Museum. Early life Orzel was born in Philadelphia in 1959 and diagnosed with FOP, a rare disease that causes tissue to ossify. In 1982 at age 23, she moved to Inglis House, a nursing-care facility, at its Belmont Avenue campus. Advocacy and association with University of Pennsylvania After moving to Inglis House, Orzel became a patient of doctor Frederick Kaplan at the University of Pennsylvania. Kaplan had never before met someone with FOP, and the disease would become his focus. Orzel gave annual talks to incoming medical students at University of Pennsylvania to help them better understand treating people with disabilities. The Mütter Museum notes that she "advocated for more research, established netw ...
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Philadelphia, Pennsylvania
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since 1854, the city has been coextensive with Philadelphia County, the most populous county in Pennsylvania and the urban core of the Delaware Valley, the nation's seventh-largest and one of world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, an English Quaker. The city served as capital of the Pennsylvania Colony during the British colonial era and went on to play a historic and vital role as the central meeting place for the nation's founding fathers whose plans and actions in Philadelphia ultimately inspired the American Revolution and the nation's inde ...
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Harry Raymond Eastlack
Harry Raymond Eastlack, Jr. (17 November 1933 – 11 November 1973) was the subject of the most recognized case of FOP (fibrodysplasia ossificans progressiva) from the 20th century. His case is also particularly acknowledged, by scientists and researchers, for his contribution to medical advancement. After suffering from a rare, disabling, and currently incurable genetic disease, Eastlack decided to have his skeleton and medical history donated to the Mütter Museum of the College of Physicians of Philadelphia in support of FOP research. His skeleton is one of the few FOP-presenting, fully articulated ones in existence, and it has proved valuable to the study of the disease. As is characteristic of FOP patients, Eastlack did not demonstrate any possible sign of a disease at birth except for a malformation of the big toes. At the time it was not recognized as the first clinical sign of FOP. It was not until 1937 when the first heterotopic ossification symptom surfaced. By the time ...
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People From Philadelphia
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
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2018 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ...
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1959 Births
Events January * January 1 - Cuba: Fulgencio Batista flees Havana when the forces of Fidel Castro advance. * January 2 - Lunar probe Luna 1 was the first man-made object to attain escape velocity from Earth. It reached the vicinity of Earth's Moon, and was also the first spacecraft to be placed in heliocentric orbit. * January 3 ** The three southernmost atolls of the Maldive archipelago ( Addu Atoll, Huvadhu Atoll and Fuvahmulah island) declare independence. ** Alaska is admitted as the 49th U.S. state. * January 4 ** In Cuba, rebel troops led by Che Guevara and Camilo Cienfuegos enter the city of Havana. ** Léopoldville riots: At least 49 people are killed during clashes between the police and participants of a meeting of the ABAKO Party in Léopoldville in the Belgian Congo. * January 6 ** Fidel Castro arrives in Havana. ** The International Maritime Organization is inaugurated. * January 7 – The United States recognizes the new Cuban government of F ...
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Skulls Unlimited International
Skulls Unlimited International, Inc. is a commercial supplier of osteological specimens located in Oklahoma City, Oklahoma. Skulls Unlimited Inc. provides a skull cleaning service, using dermestid beetles to strip the flesh from skulls and skeletons. The bones are later whitened using hydrogen peroxide. Skulls Unlimited processes approximately 25,000 skull specimens per year. History In the summer of 1986, Jay Villemarette found himself out of work after being laid off from his auto body job and started considering the possibility of working full-time with skulls. In June of that year he established Skulls Unlimited International Inc. His fascination with skulls and bones began when he was seven years old, after he found a dog skull in the woods near his home. That interest, along with encouragement from his father, led Villemarette to begin collecting other animal skulls. After graduating from high school, he collected and sold skulls in his spare time while working as an aut ...
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Curator
A curator (from la, cura, meaning "to take care") is a manager or overseer. When working with cultural organizations, a curator is typically a "collections curator" or an "exhibitions curator", and has multifaceted tasks dependent on the particular institution and its mission. In recent years the role of curator has evolved alongside the changing role of museums, and the term "curator" may designate the head of any given division. More recently, new kinds of curators have started to emerge: "community curators", "literary curators", " digital curators" and " biocurators". Collections curator A "collections curator", a "museum curator" or a "keeper" of a cultural heritage institution (e.g., gallery, museum, library or archive) is a content specialist charged with an institution's collections and involved with the interpretation of heritage material including historical artifacts. A collections curator's concern necessarily involves tangible objects of some sort—artwork, c ...
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Hospital Of The University Of Pennsylvania
The Hospital of the University of Pennsylvania (HUP) is the flagship hospital of Penn Medicine and is located in the University City section of West Philadelphia. It is consistently ranked as one of the top hospitals in the United States. History The hospital was founded at its current location in 1874 by the University of Pennsylvania School of Medicine, making it the oldest university-owned teaching hospital in the country. The hospital is located on the campus of the University of Pennsylvania, along with several other related organizations including a medical school, a nursing school, veterinary and dental schools, research laboratories and outpatient facilities including the Abramson Cancer Center and the Roberts Proton Therapy Center. The Children's Hospital of Philadelphia (CHOP) is also located on this campus. Although it engages in many collaborative efforts with Penn Medicine, CHOP is not part of the University of Pennsylvania Health System. The Chester County Ho ...
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National Geographic
''National Geographic'' (formerly the ''National Geographic Magazine'', sometimes branded as NAT GEO) is a popular American monthly magazine published by National Geographic Partners. Known for its photojournalism, it is one of the most widely read magazines of all time. The magazine was founded in 1888 as a scholarly journal, nine months after the establishment of the society, but is now a popular magazine. In 1905, it began including pictures, a style for which it became well-known. Its first color photos appeared in the 1910s. During the Cold War, the magazine committed itself to present a balanced view of the physical and human geography of countries beyond the Iron Curtain. Later, the magazine became outspoken on environmental issues. Since 2019, controlling interest has been held by The Walt Disney Company. Topics of features generally concern geography, history, nature, science, and world culture. The magazine is well known for its distinctive appearance: a thick squa ...
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Fibrodysplasia Ossificans Progressiva
Fibrodysplasia ossificans progressiva (; FOP; also called Münchmeyer disease and formerly called myositis ossificans progressiva or Stoneman disease) is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue. It is the only known medical condition where one organ system changes into another. It is a severe, disabling disorder with no current cure or treatment. FOP is caused by a mutation of the gene ACVR1. The mutation affects the body's repair mechanism, causing fibrous tissue including muscle, tendons, and ligaments to become ossified, either spontaneously or when damaged as the result of trauma. In many cases, otherwise minor injuries can cause joints to become permanently fused as new bone forms, replacing the damaged muscle tissue. This new bone formation (known as "heterotopic ossification") eventually forms a secondary skeleton and progressively restricts the patient's ability to move. ...
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International FOP Association
The International Fibrodysplasia Ossificans Progressiva Association (IFOPA) is a US-based 501(c)(3) non-profit organization supporting medical research, education and communication for those afflicted by the rare genetic condition Fibrodysplasia Ossificans Progressiva (FOP). IFOPA's mission is to fund research to find a cure for FOP while supporting, connecting, and advocating for individuals with FOP and their families, and raising awareness worldwide. IFOPA is governed by a volunteer board of directors which may range in number from 9 to 15, at least one of whom must have FOP. The association's location is 1520 Clay St., Suite H2, North Kansas City, MO, 64116, part of the Kansas City, Missouri metropolitan area. Founding and history IFOPA was founded in 1988 by Jeannie L. Peeper. Diagnosed with FOP in 1962 at age four, Peeper graduated from college in 1985 with a bachelor of arts degree in social work. Michael Zasloff, then at the National Institutes of Health (NIH), was stu ...
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University Of Pennsylvania
The University of Pennsylvania (also known as Penn or UPenn) is a private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest-regarded universities by numerous organizations and scholars. While the university dates its founding to 1740, it was created by Benjamin Franklin and other Philadelphia citizens in 1749. It is a member of the Ivy League. The university has four undergraduate schools as well as twelve graduate and professional schools. Schools enrolling undergraduates include the College of Arts and Sciences, the School of Engineering and Applied Science, the Wharton School, and the School of Nursing. Among its highly ranked graduate schools are its law school, whose first professor wrote the first draft of the United States Constitution, its medical school, the first in North America, and Wharton, the first collegiate business school. Penn's endowment is US$20.7 billio ...
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