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Carl-Gustav Groth
Carl-Gustav Groth (15 October 1933 – 16 February 2014) was a Swedish transplant surgeon. He studied in Colorado under the supervision of transplantation pioneer Thomas Starzl, and returned to Sweden to work at the Karolinska Institute and Karolinska University Hospital, where he performed the first pancreas, liver and islet cell transplantation surgeries in Sweden. Early life Groth was born in 1933 in Helsinki to Carl-Johan Groth, a businessman, and Margareta Groth (née Sonkin). He and his parents moved to Stockholm during the Second World War, when he was aged 11. He studied medicine at the Karolinska Institute, receiving an MD in 1961. Career Groth began his career at Serafimer Hospital in Stockholm, working in the department of surgery. He gained a PhD in 1965 with a thesis on red blood cell aggregation in trauma. After deciding to focus on transplantation surgery, Groth was awarded a research fellowship from the United States National Institutes of Health to study trans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plarr's Lives Of The Fellows
''Plarr's Lives of the Fellows'' is a biographical register of the fellows of the Royal College of Surgeons of England that contains over 9,000 obituaries.' The first printed volumes of the work were produced by Victor Plarr Victor Gustave Plarr (21 June 1863 – 28 January 1929) was an English poet; he is probably best known for the poem ''Epitaphium Citharistriae''. Life He was born near Strasbourg, France, of a French father from Alsace, Gustave Plarr, and an En ... (1863-1929), who was the College's librarian from 1897 until his death, and published posthumously in 1930. The last of the nine printed volumes was published in 2005 and profiled all the fellows (FRCS) known to have died between the establishment of the College in 1843 and 2002. Since 2006, ''Plarr's'' has been published online and continues to be updated with new entries monthly. References External links Biographical dictionaries {{ref-book-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions. In general, deliberately induced immunosuppression is performed to prevent the body from rejecting an organ transplant. Additionally, it is used for treating graft-versus-host disease after a bone marrow transplant, or for the treatment of auto-immune diseases such as systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, or Crohn's disease. This is typically done using medications, but may involve surgery (splenectomy), plasmapheresis, or radiation. A person who is undergoing immunosuppression, or whose immune system is weak for some other reasons (such as chemotherapy or HIV), is said to be ''immunocompromised''. Deliberately induced Administration of immunosuppressive medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haemorrhages
Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, vagina or anus, or through a puncture in the skin. Hypovolemia is a massive decrease in blood volume, and death by excessive loss of blood is referred to as exsanguination. Typically, a healthy person can endure a loss of 10–15% of the total blood volume without serious medical difficulties (by comparison, blood donation typically takes 8–10% of the donor's blood volume). The stopping or controlling of bleeding is called hemostasis and is an important part of both first aid and surgery. Types * Upper head ** Intracranial hemorrhage – bleeding in the skull. ** Cerebral hemorrhage – a type of intracranial hemorrhage, bleeding within the brain tissue itself. ** Intracerebral hemorrhage – bleeding in the brain caused by the ruptu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coronary Artery Bypass Surgery
Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage") is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve chest pain caused by CAD, slow the progression of CAD, and increase life expectancy. It aims to bypass narrowings in heart arteries by using arteries or veins harvested from other parts of the body, thus restoring adequate blood supply to the previously ischemic (deprived of blood) heart. There are two main approaches. The first uses a cardiopulmonary bypass machine, a machine which takes over the functions of the heart and lungs during surgery by circulating blood and oxygen. With the heart in arrest, harvested arteries and veins are used to connect across problematic regions—a construction known as surgical anastomosis. In the second approach, called the off-pump coronary artery bypass graft (OPCABG), these anastomoses are constructed while t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of The Seraphim
The Royal Order of the Seraphim ( sv, Kungliga Serafimerorden; ''Seraphim'' being a category of angels) is a Swedish order of chivalry created by Frederick I of Sweden, King Frederick I on 23 February 1748, together with the Order of the Sword and the Order of the Polar Star. The order has only one class with the dignity of ''Knight'' (''Member'' for women and ''Member of the Cloth'' for clergymen), and is the foremost order of Sweden. The three above-mentioned Orders together with the Order of Vasa form the Orders of His Majesty the King (Swedish language, Swedish ''Kungl. Maj:ts Orden''). A Swedish Knight of the Order of the Seraphim is not referred to as a Knight of the Seraphim, but rather as a ''Knight and Commander of the Orders of His Majesty the King'' ( sv, Riddare och Kommendör av Kunglig Majestäts Orden). This form is used because the Swedish word ''orden'' is an old plural form which indicates that a knight has to be a Commander Grand Cross or Commander of at least ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Assembly At The Karolinska Institute
The Nobel Assembly at the Karolinska Institute is a body at Karolinska Institute which awards the Nobel Prize in Physiology or Medicine. It is headquartered in the Nobel Forum on the grounds of the Karolinska Institute campus. Originally the Nobel Assembly was not a formal body but rather the collective of all professors (holders of chairs, i.e. full professors) at Karolinska Institute. In 1977 the Nobel Assembly became a separate private organization hosted by Karolinska Institute. Until 1984 all Karolinska Institute professors belonged to the Assembly; from 1984 the membership is restricted to 50 Karolinska Institute professors.Karolinska Institutet: ''Nobelpriset - den ärofyllda traditionen'' accessed on August 3, 2009 The main work involved in collecting nominations and screening no ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Islet Cell Transplantation
Islet transplantation is the transplantation of isolated islets from a donor pancreas into another person. It is an experimental treatment for type 1 diabetes mellitus. Once transplanted, the islets begin to produce insulin, actively regulating the level of glucose in the blood. Islets are usually infused into the person's liver. If the cells are not from a genetically identical donor the person's body will recognize them as foreign and the immune system will begin to attack them as with any transplant rejection. To prevent this immunosuppressant drugs are used. A study from 2005 showed that islet transplantation has progressed to the point that 58% of the people were insulin independent one year after the operation. A review published 2016 reported a 50 – 70% rate of insulin independence after five years, in five studies from leading transplant centers published 2005 – 2012. In the period from 1999 to 2004, 471 people with type 1 diabetes received islet transplants at 43 inst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xenotransplantation
Xenotransplantation (''xenos-'' from the Greek meaning "foreign" or strange), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with allotransplantation (from other individual of same species), syngeneic transplantation or isotransplantation (grafts transplanted between two genetically identical individuals of the same species) and autotransplantation (from one part of the body to another in the same person). Xenotransplantation of human tumor cells into immunocompromised mice is a research technique frequently used in pre-clinical oncology research. Human xenotransplantation offers a potential treatment for end-stage organ failure, a significant health problem in parts of the industrialized world. It also raises many novel medical, legal and ethical issues. A continuing concern is that many animals, such as pigs, have a s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bone Marrow Transplantation
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce additional normal blood cells. It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin). It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient's immune system is usually destroyed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic HSCT. HSCT remains a dangerous procedure with many possible complications; it is reserved for patients with life-threatening diseases. As survival following the procedure has increased, its use has expanded beyond cancer to autoimm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kidney Transplantation
Kidney transplant or renal transplant is the organ transplant of a kidney into a patient with end-stage kidney disease (ESRD). Kidney transplant is typically classified as deceased-donor (formerly known as cadaveric) or living-donor transplantation depending on the source of the donor organ. Living-donor kidney transplants are further characterized as genetically related (living-related) or non-related (living-unrelated) transplants, depending on whether a biological relationship exists between the donor and recipient. Before receiving a kidney transplant, a person with ESRD must undergo a thorough medical evaluation to make sure that they are healthy enough to undergo transplant surgery. If they are deemed a good candidate, they can be placed on a waiting list to receive a kidney from a deceased donor. Once they are placed on the waiting list, they can receive a new kidney very quickly, or they may have to wait many years; in the United States, the average waiting time is three t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pancreas Transplantation
A pancreas transplant is an organ transplant that involves implanting a healthy pancreas (one that can produce insulin) into a person who usually has diabetes. Overview Because the pancreas is a vital organ, performing functions necessary in the digestion process, the recipient's native pancreas is left in place, and the donated pancreas is attached in a different location. In the event of rejection of the new pancreas, which would quickly cause life-threatening diabetes, there would be a significant chance the recipient would not survive very well for long without the native pancreas, however dysfunctional, still in place. The healthy pancreas comes from a donor who has just died or it may be a partial pancreas from a living donor. At present, pancreas transplants are usually performed in persons with insulin-dependent diabetes, who can develop severe complications. Patients with the most common, and deadliest, form of pancreatic cancer ( pancreatic adenomas, which are usually m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
