Capripoxvirus
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Capripoxvirus
''Capripoxvirus'' is a genus of viruses in the subfamily ''Chordopoxvirinae'' and the family ''Poxviridae''. Capripoxviruses are among the most serious of all animal poxviruses. All CaPV are notifiable diseases to the OIE (World Organisation for Animal Health). Sheep, goat, and cattle serve as natural hosts. These viruses cause negative economic consequences by damaging hides and wool and forcing the establishment of trade restrictions in response to an outbreak. The genus consists of three species: sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV). They share no serological relationship with camel pox, horse pox, or avian poxes. Capripoxviruses for sheeppox and goatpox infect only sheep and goat respectively. However, it is probable that North American relatives, the mountain goat and mountain sheep, may be susceptible to the strains but has not been experimentally proven. Lumpy skin disease virus affects primarily cattle, but studies have been show ...
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Chordopoxvirinae
''Chordopoxvirinae'' is a subfamily of viruses in the family ''Poxviridae''. Humans, vertebrates, and arthropods serve as natural hosts. Currently, 52 species are placed in this subfamily, divided among 18 genera. Diseases associated with this subfamily include smallpox. Four genera in this subfamily contain species that infect humans: ''Molluscipoxvirus, Orthopoxvirus, Parapoxvirus'', and ''Yatapoxvirus''. Virology The virions are generally enveloped though the intracellular mature virion form of the virus, which contains a different envelope, and is also infectious. They vary in their shape depending upon the species, but are generally shaped like a brick or as an oval form similar to a rounded brick because they are wrapped by the endoplasmic reticulum. The virion is exceptionally large, around 200 nm in diameter and 300 nm in length, and carries its genome in a single, double-stranded segment of DNA. Genomes are linear, around 130-375kb in length. Lifecycle Viral r ...
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Poxviridae
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox. Four genera of poxviruses may infect humans: ''Orthopoxvirus'', ''Parapoxvirus'', ''Yatapoxvirus'', ''Molluscipoxvirus''. ''Orthopoxvirus'': smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus; ''Parapoxvirus'': orf virus, pseudocowpox, bovine papular stomatitis virus; ''Yatapoxvirus'': tanapox virus, yaba monkey tumor virus; ''Molluscipoxvirus'': molluscum contagiosum virus (MCV). The most common are vaccinia (seen on the Indian subcontinent) and molluscum contagiosum, but monkeypox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster. Etymology ...
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Lumpy Skin Disease Virus
Lumpy skin disease (LSD) is an infectious disease in cattle caused by a virus of the family ''Poxviridae'', also known as Neethling virus. The disease is characterized by large fever, enlarged superficial lymph nodes and multiple nodules (measuring in diameter) on the skin and mucous membranes (including those of the respiratory and gastrointestinal tracts). Infected cattle also may develop edematous swelling in their limbs and exhibit lameness. The virus has important economic implications since affected animals tend to have permanent damage to their skin, lowering the commercial value of their hide. Additionally, the disease often results in chronic debility, reduced milk production, poor growth, infertility, abortion, and sometimes death. Onset of fever occurs almost one week after infection by the virus. This initial fever may exceed and persist for one week. At this time, all of the superficial lymph nodes become enlarged. The nodules, in which the disease is characterized ...
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Sheeppox Virus
Sheeppox (or sheep pox, known as in Latin, in French, in German) is a highly contagious disease of sheep caused by a poxvirus different from the benign orf (or contagious ecthyma). This virus is in the family ''Poxviridae'' and genus '' Capripoxvirus''. ''Sheeppox virus'' (SPV) is the most severe of all the animal pox diseases and can result in some of the most significant economic consequences due to poor wool and leather quality. Goatpox is a similar disease of goats, caused by a virus antigenically distinct from ''sheeppox virus''. Virology Structure Sheeppox virus is approximately 150 kbp and shares 96% and 97% nucleotide identity with goatpox virus and lumpy skin disease virus, respectively. This virus has a linear, dsDNA genome and is thus apart of group I according to the Baltimore Classification System. The virus has a complex coat and capsid symmetry. Host The hosts for sheeppox virus are all breeds of wild and domesticated sheep. However, those animals nativ ...
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Goatpox Virus
Variola caprina (goat pox) is a contagious viral disease caused by ''Goatpox virus'', a pox virus that affects goats. The virus usually spreads via the respiratory system, and sometimes spreads through abraded skin. It is most likely to occur in crowded stock. Sources of the virus include cutaneous lesions, saliva, nasal secretions and faeces. There are two types of the disease: the papulo-vesicular form and the nodular form (stone pox). The incubation period is usually 8–13 days, but it may be as short as four days. It is thought the same virus spreads sheep pox, to which European sheep breeds are highly susceptible. The virus may be present in dried scabs for up to six months. In endemic areas the morbidity rate is 70–90% and the mortality rate is 5–10%. The mortality rate may reach nearly 100% in imported animals. Resistant animals may show only a mild form of the disease, which may be missed as only a few lesions are present, usually around the ears or the tail. Sp ...
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Elsevier
Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell'', the ScienceDirect collection of electronic journals, '' Trends'', the '' Current Opinion'' series, the online citation database Scopus, the SciVal tool for measuring research performance, the ClinicalKey search engine for clinicians, and the ClinicalPath evidence-based cancer care service. Elsevier's products and services also include digital tools for data management, instruction, research analytics and assessment. Elsevier is part of the RELX Group (known until 2015 as Reed Elsevier), a publicly traded company. According to RELX reports, in 2021 Elsevier published more than 600,000 articles annually in over 2,700 journals; as of 2018 its archives contained over 17 million documents and 40,000 e-books, with over one billion annual downloads. Researchers have criticized Elsevier for its high profit marg ...
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St Louis, Missouri
St. Louis () is the second-largest city in Missouri, United States. It sits near the confluence of the Mississippi and the Missouri Rivers. In 2020, the city proper had a population of 301,578, while the bi-state metropolitan area, which extends into Illinois, had an estimated population of over 2.8 million, making it the largest metropolitan area in Missouri and the second-largest in Illinois. Before European settlement, the area was a regional center of Native American Mississippian culture. St. Louis was founded on February 14, 1764, by French fur traders Gilbert Antoine de St. Maxent, Pierre Laclède and Auguste Chouteau, who named it for Louis IX of France. In 1764, following France's defeat in the Seven Years' War, the area was ceded to Spain. In 1800, it was retroceded to France, which sold it three years later to the United States as part of the Louisiana Purchase; the city was then the point of embarkation for the Corps of Discovery on the Lewis and Clark Ex ...
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Notifiable Disease
A notifiable disease is any disease that is required by law to be reported to government authorities. The collation of information allows the authorities to monitor the disease, and provides early warning of possible outbreaks. In the case of livestock diseases, there may also be the legal requirement to kill the infected livestock upon notification. Many governments have enacted regulations for reporting of both human and animal (generally livestock) diseases. Global Human The World Health Organization's ''International Health Regulations 1969'' require disease reporting to the organization in order to help with its global surveillance and advisory role. The current (1969) regulations are rather limited with a focus on reporting of three main diseases: cholera, yellow fever and plague. Smallpox was a contagious disease during the 18th-20th century. It was endemic until mass vaccination, after which WHO certified Smallpox to be eradicated. This marked the first human diseas ...
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World Organisation For Animal Health
The World Organisation for Animal Health (WOAH), formerly the (OIE), is an intergovernmental organization coordinating, supporting and promoting animal disease control. Mission and status The main objective of the WOAH is to control epizootic diseases and thus to prevent their spread. Other objectives consist of: transparency, scientific information, international solidarity, sanitary safety, the promotion of Veterinary Services, food safety and animal welfare. It is recognized as a reference organisation by the World Trade Organization (WTO) and in 2018 had a total of 182 member states. Its newest member state is Saint Lucia. The WOAH maintains permanent relations with 45 other international and regional organisations and has Regional and sub-regional Offices on every continent. The WOAH does not depend on the UN system; its autonomy is both institutional and financial and its activities are governed by its own constitutional texts. Since its first General Session held in ...
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