Cancer And Leukemia Group B
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Cancer And Leukemia Group B
Cancer and Leukemia Group B (CALGB; former name: Acute Leukemia Group B, ALGB) is a cancer research cooperative group in the United States. CALGB research is focused on seven major disease areas: leukemia, lymphoma, breast cancer, lung cancer, gastrointestinal malignancies, genito-urinary malignancies, and melanoma. In each of these areas, multi-modality treatment programs are designed by national experts. CALGB is headquartered at the University of Chicago in Chicago, Illinois and maintains its statistical centers at Mayo Clinic in Rochester, Minnesota and Duke University in Durham, North Carolina. History The group that was to become known as the CALGB got its roots when James F. Holland initiated a clinical trial for acute leukemia in 1953 while at the National Cancer Institute. In 1954, before the trial was complete, Holland moved to Roswell Park Comprehensive Cancer Center (then known as Roswell Park Memorial Institute), but the new chief of oncology Gordon Zubrod at th ...
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Cancer and Leukemia Group B (CALGB; former name: Acute Leukemia Group B, ALGB) is a cancer research cooperative group in the United States. CALGB research is focused on seven major disease areas: leukemia, lymphoma, breast cancer, lung cancer, gastrointestinal malignancies, genito-urinary malignancies, and melanoma. In each of these areas, multi-modality treatment programs are designed by national experts. CALGB is headquartered at the University of Chicago in Chicago, Illinois and maintains its statistical centers at Mayo Clinic in Rochester, Minnesota and Duke University in Durham, North Carolina. History The group that was to become known as the CALGB got its roots when James F. Holland initiated a clinical trial for acute leukemia in 1953 while at the National Cancer Institute. In 1954, before the trial was complete, Holland moved to Roswell Park Comprehensive Cancer Center (then known as Roswell Park Memorial Institute), but the new chief of oncology Gordon Zubrod at the ...
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National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship. NCI is the oldest and has the largest budget and research program of the 27 institutes and centers of the NIH ($6.9 billion in 2020). It fulfills the majority of its mission via an extramural program that provides grants for cancer research. Additionally, the National Cancer Institute has intramural research programs in Bethesda, Maryland, and at the Frederick National Laboratory for Cancer Research at Fort Detrick in Frederick, Maryland. The NCI receives more than in funding each ...
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Eastern Cooperative Oncology Group
The Eastern Cooperative Oncology Group (ECOG) began in 1955 as one of the first publicly funded cooperative groups to perform multi-center clinical trials for cancer research. A cooperative group in oncology constitutes a large network of private and public medical institutions developing protocols for cancer treatments. Institutional members include universities, medical centers, governments, and other cooperative groups. Research results are often provided through scientific publications, but the group also works closely with the pharmaceutical industry to test potential cancer drugs. According to ECOG's website, there are "more than 90 active clinical trials in all types of adult malignancies. Annual accrual is 6,000 patients, with more than 20,000 patients in follow-up." ECOG's coordinating center is based in Boston, Massachusetts while its Group Chair's office is located in Philadelphia, Pennsylvania Philadelphia, often called Philly, is the largest city in th ...
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Children's Oncology Group
The Children's Oncology Group (COG), a clinical trials group supported by the National Cancer Institute (NCI), is the world's largest organization devoted exclusively to pediatric cancer research. The COG conducts a spectrum of clinical research and translational research trials for infants, children, adolescents, and young adults with cancer. Almost all centers that treat children with cancer in the US and Canada are part of the COG, with more than 200 centers in the United States, Canada, Switzerland, the Netherlands, Australia, and New Zealand. The member institutions have multidisciplinary teams consisting of physicians, research scientists, nurses, psychologists, pharmacists and other specialists. The group, with more than 7,500 experts worldwide, has nearly 100 active clinical-translational trials open at any given time. These trials include treatment for many types of childhood cancers, studies aimed at determining the underlying biology of these diseases, and trials invo ...
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Diagnostic Imaging
Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging. Measurement and recording techniques that are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), electrocardiography (ECG), and others, represent other technologies that produce data susceptible to representation as a parameter graph versus time or maps that contain data about the measurement lo ...
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Radiotherapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. Ionizing radiation works by damaging the DNA of cancerous tissue l ...
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Lincoln, Rhode Island
Lincoln is a town in Providence County, Rhode Island, United States. The population was 22,529 at the 2020 census. Lincoln is located in northeastern Rhode Island, north of Providence. Lincoln is part of the Providence metropolitan statistical area and the Greater Boston combined statistical area. Lincoln was settled in the 17th century as part of the Louisquisset grant, and several colonial stone-enders still exist in the town. Lincoln Woods State Park is located within the town. Limestone quarrying has occurred there since colonial times at the village of Lime Rock. Lincoln was a part of the town of Smithfield until 1871, when it was split off and named in honor of Abraham Lincoln. Lincoln became an important mill town in the late 19th century, with many textile factories running along the Blackstone River. Lincoln's villages include Manville, Albion, Lime Rock, Lonsdale, Fairlawn, Quinnville, and Saylesville. In 2008, the town was ranked #63 in Money Magazine's "Best P ...
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Quality Assurance Review Center
The Imaging and Radiation Oncology Core (IROC) is a center for the evaluation of data produced by clinical trials funded by the National Cancer Institute, as part of the National Clinical Trials Network "to provide integrated radiation oncology and diagnostic imaging quality control programs... thereby assuring high quality data for clinical trials designed to improve the clinical outcomes for cancer patients worldwide." Centers There are currently five centers: IROC Houston QA Center, at the MD Anderson Cancer Center IROC Ohio QA Center, at Ohio State University Wexner Medical Center and James Comprehensive Cancer Center. IROC Rhode Island QA Center in Lincoln, Rhode Island, administered by the University of Massachusetts Medical School IROC Philadelphia (RT) QA Center, at the ACR Research center in Philadelphia, IROC Philadelphia (Imaging) QA Center, at the ACR Research center in Philadelphia, IROC St Louis QA Center at Washington University History The history of the ...
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Alliance For Clinical Trials In Oncology
The Alliance for Clinical Trials in Oncology is a national clinical trials network sponsored by the National Cancer Institute (NCI) that consists of about 10,000 cancer specialists at hospitals, medical centers, and community clinics across the United States and Canada. The Alliance develops and conducts clinical trials with promising new cancer therapies, and utilizes scientific research to develop treatment and prevention strategies for cancer, as well as researching methods to alleviate side effects of cancer and cancer treatments. The Alliance seeks to reduce the impact of cancer on people by uniting a broad community of scientists and clinicians from many disciplines, committed to discovering, validating and disseminating effective strategies for the prevention and treatment of cancer. The Alliance conducts trials in the following disease and modality areas: breast, gastrointestinal (GI), genitourinary (GU), leukemia, lymphoma, myeloma, neuro-oncology, respiratory, exper ...
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North Central Cancer Treatment Group
The North Central Cancer Treatment Group (NCCTG) is an international clinical research group sponsored by the National Cancer Institute. The NCCTG consists of a network of cancer specialists at community clinics, hospitals and medical centers in the United States, Canada and Mexico. The research base for NCCTG is located at Mayo Clinic in Rochester, Minnesota Minnesota () is a state in the upper midwestern region of the United States. It is the 12th largest U.S. state in area and the 22nd most populous, with over 5.75 million residents. Minnesota is home to western prairies, now given over to .... External linksNorth Central Cancer Treatment Group References Cancer organizations based in the United States Medical and health organizations based in Minnesota {{US-health-org-stub ...
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Children's Cancer Study Group
The Children's Oncology Group (COG), a clinical trials group supported by the National Cancer Institute (NCI), is the world's largest organization devoted exclusively to pediatric cancer research. The COG conducts a spectrum of clinical research and translational research trials for infants, children, adolescents, and young adults with cancer. Almost all centers that treat children with cancer in the US and Canada are part of the COG, with more than 200 centers in the United States, Canada, Switzerland, the Netherlands, Australia, and New Zealand. The member institutions have multidisciplinary teams consisting of physicians, research scientists, nurses, psychologists, pharmacists and other specialists. The group, with more than 7,500 experts worldwide, has nearly 100 active clinical-translational trials open at any given time. These trials include treatment for many types of childhood cancers, studies aimed at determining the underlying biology of these diseases, and trials invo ...
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Buffalo, New York
Buffalo is the second-largest city in the U.S. state of New York (behind only New York City) and the seat of Erie County. It is at the eastern end of Lake Erie, at the head of the Niagara River, and is across the Canadian border from Southern Ontario. With a population of 278,349 according to the 2020 census, Buffalo is the 78th-largest city in the United States. The city and nearby Niagara Falls together make up the two-county Buffalo–Niagara Falls Metropolitan Statistical Area (MSA), which had an estimated population of 1.1 million in 2020, making it the 49th largest MSA in the United States. Buffalo is in Western New York, which is the largest population and economic center between Boston and Cleveland. Before the 17th century, the region was inhabited by nomadic Paleo-Indians who were succeeded by the Neutral, Erie, and Iroquois nations. In the early 17th century, the French began to explore the region. In the 18th century, Iroquois land surrounding Buffalo Creek ...
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