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COVID-19 Vaccination In Thailand
COVID-19 vaccination in Thailand is an ongoing mass immunization in response to the ongoing pandemic in the country. Background In November 2020, the authorities ordered 26 million doses of vaccine from AstraZeneca, which reported 70% overall efficacy. It requires 2 doses of vaccine per person, so the quantity ordered would only cover 13 million people. Prayut cabinet later approved budget for ordering 35 million additional doses in January 2021. Siam Bioscience, a company owned by King Vajiralongkorn, will received technological transfer for co-investment. The authorities also imported 2 million doses of vaccine from Sinovac, a Chinese company which Thai conglomerate Charoen Pokphand invested in, during February to April 2021. Likewise, the Thai government also stepped up its attempt to produce its homegrown vaccines amidst criticism, with "ChulaCov19" and set to begin trials in May 2021. Phase I testing of the NDV-HXP-S vaccine began at Mahidol University in March 2021. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thailand
Thailand ( ), historically known as Siam () and officially the Kingdom of Thailand, is a country in Southeast Asia, located at the centre of the Indochinese Peninsula, spanning , with a population of almost 70 million. The country is bordered to the north by Myanmar and Laos, to the east by Laos and Cambodia, to the south by the Gulf of Thailand and Malaysia, and to the west by the Andaman Sea and the extremity of Myanmar. Thailand also shares maritime borders with Vietnam to the southeast, and Indonesia and India to the southwest. Bangkok is the nation's capital and largest city. Tai peoples migrated from southwestern China to mainland Southeast Asia from the 11th century. Indianised kingdoms such as the Mon, Khmer Empire and Malay states ruled the region, competing with Thai states such as the Kingdoms of Ngoenyang, Sukhothai, Lan Na and Ayutthaya, which also rivalled each other. European contact began in 1511 with a Portuguese diplomatic mission to Ayutthaya, w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ministry Of Public Health (Thailand)
The Ministry of Public Health (MOPH; th, กระทรวงสาธารณสุข, ) is a Thai governmental body responsible for the oversight of public health in Thailand. It is commonly referred to in Thailand by its abbreviation ''so tho'' (). History In Thailand before 1888 there were no permanent, public hospitals to provide care to sick people. Temporary hospitals were set up to care for patients during epidemics, then disbanded when the epidemic subsided. Under King Chulalongkorn (Rama V) a hospital was constructed and completed in 1888 and named "Siriraj Hospital" in commemoration of the king's young son, Prince Siriraj Kakudhabhand, who had died of dysentery. King Vajiravudh, King Chulalongkorn's successor, established Department of Health on 27 November 1918. During the reign of King Rama VIII, the Ministry of Public Health was established on 10 March 1942 as a result of the enactment of the Ministries and Departments Reorganization Act (Amendment No. 3) of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Sydney
The University of Sydney (USYD), also known as Sydney University, or informally Sydney Uni, is a public research university located in Sydney, Australia. Founded in 1850, it is the oldest university in Australia and is one of the country's six sandstone universities. The university comprises eight academic faculties and university schools, through which it offers bachelor, master and doctoral degrees. The university consistently ranks highly both nationally and internationally. QS World University Rankings ranked the university top 40 in the world. The university is also ranked first in Australia and fourth in the world for QS graduate employability. It is one of the first universities in the world to admit students solely on academic merit, and opened their doors to women on the same basis as men. Five Nobel and two Crafoord laureates have been affiliated with the university as graduates and faculty. The university has educated eight Australian prime ministers, including ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subunit Vaccine
A subunit vaccine is a vaccine that contains purified parts of the pathogen that are antigenic, or necessary to elicit a protective immune response. A "subunit" vaccine doesn't contain the whole pathogen, unlike live attenuated or inactivated vaccine, but contains only the antigenic parts such as proteins, polysaccharides or peptides. Because the vaccine doesn't contain "live" components of the pathogen, there is no risk of introducing the disease, and is safer and more stable than vaccine containing whole pathogens. Other advantages include being well-established technology and being suitable for immunocompromised individuals. Disadvantages include being relatively complex to manufacture compared to some vaccines, possibly requiring adjuvants and booster shots, and requiring time to examine which antigenic combinations may work best. Mechanism Subunit vaccines contain fragments of the pathogen, such as protein or polysaccharide, whose combinations are carefully selected to i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plant Expressed Vaccine
Plant expressed vaccine or project GreenVax In 2005 DARPA’s Accelerated Manufacture of Pharmaceuticals (AMP) program was created In response to emerging and novel biologic threats. In 2009 DARPA offered a government contract for a Non-GMO plant-based systems expressing recombinant proteins, due to The 2009 H1N1 swine flu pandemic that highlighted the national need for rapid and agile vaccine manufacturing capabilities. The Texas A&M University and a Texas company (GreenVax LLC, later renamed to Caliber Biotherapeutics LLC and ultimately acquired by iBio, Inc.) have been awarded a $40 million U.S. Department of Defense grant to develop a plant expressed vaccine made from tobacco. While egg-based vaccines typically take more than six months to develop after a virus is isolated, the new process will take only four to six weeks. The vice chancellor for research at A&M System declared that if the project works it will be one of the largest and most capable vaccine facilities in the worl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RNA Vaccine
An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules of antigen-encoding mRNA into immune cells, which use the designed mRNA as a blueprint to build foreign protein that would normally be produced by a pathogen (such as a virus) or by a cancer cell. These protein molecules stimulate an adaptive immune response that teaches the body to identify and destroy the corresponding pathogen or cancer cells. The mRNA is delivered by a co-formulation of the RNA encapsulated in lipid nanoparticles that protect the RNA strands and help their absorption into the cells. Reactogenicity, the tendency of a vaccine to produce adverse reactions, is similar to that of conventional non-RNA vaccines. People susceptible to an autoimmune response may have an adverse reaction to messenger RNA vaccines. The advantages of mRNA vaccines over traditional vaccines are ease of design, speed and lower cost ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chulalongkorn University
Chulalongkorn University (CU, th, จุฬาลงกรณ์มหาวิทยาลัย, ), nicknamed Chula ( th, จุฬาฯ), is a public and autonomous research university in Bangkok, Thailand. The university was originally founded during King Chulalongkorn's reign as a school for training royal pages and civil servants in 1899 (B.E. 2442) at the Grand Palace of Thailand. It was later established as a national university in 1917, making it the oldest institute of higher education in Thailand. During the reign of Chulalongkorn's son, King Vajiravudh, the Royal Pages School became the Civil Service College of King Chulalongkorn. The Rockefeller Foundation was instrumental in helping the college form its academic foundation. On 26 March 1917, King Vajiravudh renamed the college "Chulalongkorn University". Chulalongkorn University is a comprehensive and research-intensive university. It is ranked as the best university in Thailand in many surveys, quality of st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital subscribers. It also is a producer of popular podcasts such as '' The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national " newspaper of record". For print it is ranked 18th in the world by circulation and 3rd in the U.S. The paper is owned by the New York Times Company, which is publicly traded. It has been governed by the Sulzberger family since 1896, through a dual-class share structure after its shares became publicly traded. A. G. Sulzberger, the paper's publisher and the company's chairman, is the fifth generation of the family to head the pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inactivated Vaccine
An inactivated vaccine (or killed vaccine) is a vaccine consisting of virus particles, bacteria, or other pathogens that have been grown in culture and then killed to destroy disease-producing capacity. In contrast, live vaccines use pathogens that are still alive (but are almost always attenuated, that is, weakened). Pathogens for inactivated vaccines are grown under controlled conditions and are killed as a means to reduce infectivity and thus prevent infection from the vaccine. Inactivated vaccines were first developed in the late 1800s and early 1900s for cholera, plague, and typhoid. Today, inactivated vaccines exist for many pathogens, including influenza, polio (IPV), rabies, hepatitis A and pertussis. Because inactivated pathogens tend to produce a weaker response by the immune system than live pathogens, immunologic adjuvants and multiple "booster" injections may be required in some vaccines to provide an effective immune response against the pathogen. Attenuated vacci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Vector Vaccine
A viral vector vaccine is a vaccine that uses a viral vector to deliver genetic material ( DNA), which can be transcribed by the recipient's host cells as mRNA coding for a desired protein (or: antigen) to elicit an immune response. , six viral vector vaccines have been authorized for use in humans in at least one country: four COVID-19 vaccines and two Ebola vaccines. Technology Viral vector vaccines use a modified version of one virus as a vector to deliver to a cell a nucleic acid coding for an antigen for another infectious agent. Viral vector vaccines do not cause infection with either the virus used as the vector, or the source of the antigen. The genetic material it delivers does not integrate into a person's genome. Viral vector vaccines enable antigen expression within cells and induce a robust cytotoxic T cell response, unlike subunit vaccines which only confer humoral immunity. Most viral vectors are designed to be incapable of replication because the necessary gene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virulent Newcastle Disease
Virulent Newcastle disease (VND), formerly exotic Newcastle disease, is a contagious viral avian disease affecting many domestic and wild bird species; it is transmissible to humans. Though it can infect humans, most cases are non-symptomatic; rarely it can cause a mild fever and influenza-like symptoms and/or conjunctivitis in humans. Its effects are most notable in domestic poultry due to their high susceptibility and the potential for severe impacts of an epizootic on the poultry industries. It is endemic to many countries. No treatment for VND is known, but the use of prophylactic vaccines and sanitary measures reduces the likelihood of outbreaks. The disease is caused by Newcastle disease virus (NDV), an avulavirus. Strains of Newcastle disease virus have been used to treat cancer in humans, since the virus appears to preferentially infect and kill cancerous cells. Strains of Newcastle disease virus have also been used to create viral vector vaccine candidates against Ebol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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