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CC398
CC398 or MRSA CC398 is a new variant of MRSA that has emerged in animals and is found in intensively reared production animals (primarily pigs, but also cattle and poultry), where it can be transmitted to humans as LA-MRSA (livestock-associated MRSA). A 2009 study shows, however, that dissemination of CC398 from exposed humans to other, non-exposed humans is infrequent. Though dangerous to humans, CC398 is often asymptomatic in food-producing animals. In a single study conducted in Denmark, MRSA was shown to originate in livestock and spread to humans, though the MRSA strain may have originated in humans and was transmitted to livestock. A 2011 study reported 47% of the meat and poultry sold in surveyed U.S. grocery stores was contaminated with S. aureus, and of those 5–24.4% of the total were resistant to at least three classes of antibiotics. "Now we need to determine what this means in terms of risk to the consumer," said Dr. Keim, a co-author of the paper. Some samples of com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MRSA
Methicillin-resistant ''Staphylococcus aureus'' (MRSA) is a group of Gram-positive bacteria that are genetically distinct from other strains of ''Staphylococcus aureus''. MRSA is responsible for several difficult-to-treat infections in humans. It caused more than 100,000 deaths attributable to antimicrobial resistance in 2019. MRSA is any strain of ''S. aureus'' that has developed (through natural selection) or acquired (through horizontal gene transfer) a multiple drug resistance to beta-lactam antibiotics. Beta-lactam (β-lactam) antibiotics are a broad-spectrum group that include some penams (penicillin derivatives such as methicillin and oxacillin) and cephems such as the cephalosporins. Strains unable to resist these antibiotics are classified as methicillin-susceptible ''S. aureus'', or MSSA. MRSA is common in hospitals, prisons, and nursing homes, where people with open wounds, invasive devices such as catheters, and weakened immune systems are at greater risk of hea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intensive Animal Farming
Intensive animal farming or industrial livestock production, also known by its opponents as factory farming and macro-farms, is a type of intensive agriculture, specifically an approach to animal husbandry designed to maximize production, while minimizing costs. To achieve this, agribusinesses keep livestock such as cattle, poultry, and fish at high stocking densities, at large scale, and using modern machinery, biotechnology, and global trade."EU tackles BSE crisis" BBC News, November 29, 2000. The main products of this industry are , and |
Politiken
''Politiken'' is a leading Danish daily broadsheet newspaper, published by JP/Politikens Hus in Copenhagen, Denmark. It was founded in 1884 and played a role in the formation of the Danish Social Liberal Party. Since 1970 it has been independent of the party but maintains a liberal stance. It now runs an online newspaper, ''politiken.dk''. The paper's design has won several international awards, and a number of its journalists have won the Cavling Prize. History and profile ''Dagbladet Politiken'' was founded on 1 October 1884 in Copenhagen by Viggo Hørup, Edvard Brandes and Hermann Bing. Hørup and Brandes formed the newspaper after being fired as editors from the ''Morgenbladet'' over political differences. Hørup led the paper as editor-in-chief for fifteen years from its start in 1884. In 1904, the tabloid ''Ekstra Bladet'' was founded as a supplement to ''Politiken ''and was later spun off as an independent newspaper on 1 January 1905. The paper established its present ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fur Farming
Fur farming is the practice of breeding or raising certain types of animals for their fur. Most of the world's farmed fur is produced by European farmers. In 2018, there were 5,000 fur farms in the EU, all located across 22 countries; these areas of production collectively accounted for 50% of the global production of farmed fur. The EU accounts for 63% of global mink production and 70% of fox production. Denmark was the leading mink-producing country, accounting for approximately 28% of world production. The top three fur producers are Denmark (formerly), Poland and China. Finland is the largest United States supplier of fox pelts. The United States is a major exporter of fur skins. Major export markets include China, Russia, Canada, and the EU. Exports to Asia as a share of total exports grew from 22% in 1998 to 47% in 2002. As of 2012, Russia was reported to be the world's biggest sales market for fur. China has been the world's largest importer of fur pelts and the largest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mink
Mink are dark-colored, semiaquatic, carnivorous mammals of the genera ''Neogale'' and '' Mustela'' and part of the family Mustelidae, which also includes weasels, otters, and ferrets. There are two extant species referred to as "mink": the American mink and the European mink. The extinct sea mink was related to the American mink but was much larger. The American mink's fur has been highly prized for use in clothing. Their treatment on fur farms has been a focus of animal rights and animal welfare activism. American mink have established populations in Europe (including Great Britain and Denmark) and South America. Some people believe this happened after the animals were released from mink farms by animal rights activists, or otherwise escaped from captivity. In the UK, under the Wildlife and Countryside Act 1981, it is illegal to release mink into the wild. In some countries, any live mink caught in traps must be humanely killed. American mink are believed by some to have c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ritzau
Ritzaus Bureau A/S, or Ritzau for short, sometimes stylized as /ritzau/, is a Danish news agency founded by Erik Ritzau in 1866. It collaborates with three other Scandinavian news agencies to provide Nordic News, an English-language Scandinavian news service. It is based in Copenhagen and Lars Vesterløkke is editor-in-chief and CEO of the company. History Ritzaus Bureau was founded by Erik Nicolai Ritzau in Copenhagen on 1 February 1866 under the name Nordisk Centralbureau for Telegrammer. The agency received international news by telegram from Wolffs Bureau (now Deutsche Presse-Agentur, DPA) in Berlin. Erik Ritzau died in 1904. His son, Lauritz Ritzau, was CEO of the company from 1916 to 1958. The Ritzau family sold Ritzaus Bureau to the Danish newspapers in 1947. In 2007, DR became a co-owner of the agency. The company form was changed from an ''interessentskab'' (I/S) to an ''aktieselskab'' (A/S) in 2012. Operations Ritzau collaborates with three other Scandinavian ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carbapenem Resistant Enterobacteriaceae
Carbapenem-resistant Enterobacteriaceae (CRE) or carbapenemase-producing Enterobacteriaceae (CPE) are Gram-negative bacteria that are resistant to the carbapenem class of antibiotics, considered the drugs of last resort for such infections. They are resistant because they produce an enzyme called a carbapenemase that disables the drug molecule. The resistance can vary from moderate to severe. Enterobacteriaceae are common commensals and infectious agents. Experts fear CRE as the new "superbug". The bacteria can kill up to half of patients who get bloodstream infections. Tom Frieden, former head of the Centers for Disease Control and Prevention has referred to CRE as "nightmare bacteria". Examples of enzymes found in certain types of CRE are KPC (''Klebsiella pneumoniae'' carbapenemase) and NDM (New Delhi Metallo-beta-lactamase). KPC and NDM are enzymes that break down carbapenems and make them ineffective. Both of these enzymes, as well as the enzyme VIM (Verona Integron-Mediated ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Necrotizing Fasciitis
Necrotizing fasciitis (NF), also known as flesh-eating disease, is a bacterial infection that results in the death of parts of the body's soft tissue. It is a severe disease of sudden onset that spreads rapidly. Symptoms usually include red or purple skin in the affected area, severe pain, fever, and vomiting. The most commonly affected areas are the limbs and perineum. Typically, the infection enters the body through a break in the skin such as a cut or burn. Risk factors include poor immune function such as from diabetes or cancer, obesity, alcoholism, intravenous drug use, and peripheral artery disease. It does not typically spread between people. The disease is classified into four types, depending on the infecting organism. Between 55 and 80% of cases involve more than one type of bacteria. Methicillin-resistant ''Staphylococcus aureus'' (MRSA) is involved in up to a third of cases. Medical imaging is often helpful to confirm the diagnosis. Necrotizing fasciitis may b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Staphylococcus Aureus
''Staphylococcus aureus'' is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. It is often positive for catalase and nitrate reduction and is a facultative anaerobe that can grow without the need for oxygen. Although ''S. aureus'' usually acts as a commensal of the human microbiota, it can also become an opportunistic pathogen, being a common cause of skin infections including abscesses, respiratory infections such as sinusitis, and food poisoning. Pathogenic strains often promote infections by producing virulence factors such as potent protein toxins, and the expression of a cell-surface protein that binds and inactivates antibodies. ''S. aureus'' is one of the leading pathogens for deaths associated with antimicrobial resistance and the emergence of antibiotic-resistant strains, such as methicillin-resistant ''S. aureus'' (MRSA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxic Shock Syndrome
Toxic shock syndrome (TSS) is a condition caused by bacterial toxins. Symptoms may include fever, rash, skin peeling, and low blood pressure. There may also be symptoms related to the specific underlying infection such as mastitis, osteomyelitis, necrotising fasciitis, or pneumonia. TSS is typically caused by bacteria of the ''Streptococcus pyogenes'' or ''Staphylococcus aureus'' type, though others may also be involved. Streptococcal toxic shock syndrome is sometimes referred to as toxic-shock-like syndrome (TSLS). The underlying mechanism involves the production of superantigens during an invasive streptococcus infection or a localized staphylococcus infection. Risk factors for the staphylococcal type include the use of very absorbent tampons, skin lesions in young children characterized by fever, low blood pressure, rash, vomiting and/or diarrhea, and multiorgan failure. Diagnosis is typically based on symptoms. Treatment includes intravenous fluids, antibiotics, incision ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
XF-73
XF-73 (Exeporfinium chloride) is an experimental drug candidate. It is an anti-microbial that works via weakening bacteria cell walls. It is a potential treatment for methicillin-resistant ''Staphylococcus aureus'' (MRSA) and possibly ''Clostridium difficile''. It is being developed by Destiny Pharma Ltd. Structurally, it is a dicationic porphyrin Porphyrins ( ) are a group of heterocyclic macrocycle organic compounds, composed of four modified pyrrole subunits interconnected at their α carbon atoms via methine bridges (=CH−). The parent of porphyrin is porphine, a rare chemical com .... It has completed a phase I clinical trial for nasal decolonisation of MRSA—being tested against 5 bacterial strains. It seems unlikely to cause MRSA to develop resistance to it. In 2014, a phase 1 clinical trial for nasal administration was run. , another phase 1 clinical trial (for nasal administration) completed recruiting in 2016 but no results have been posted. References ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Teixobactin
Teixobactin () is a peptide-like secondary metabolite of some species of bacteria, that kills some gram-positive bacteria. It appears to belong to a new class of antibiotics, and harms bacteria by binding to lipid II and lipid III, important precursor molecules for forming the cell wall. Teixobactin was discovered using a new method of culturing bacteria in soil, which allowed researchers to grow a previously unculturable bacterium now named ''Eleftheria terrae'', which produces the antibiotic. Teixobactin was shown to kill ''Staphylococcus aureus'' and ''Mycobacterium tuberculosis''. History In January 2015, a collaboration of four institutes in the US and Germany together with two pharmaceutical companies, reported that they had isolated and characterized a new antibiotic, killing "without detectable resistance." Teixobactin was discovered by screening previously unculturable bacteria present in a sample of soil from "a grassy field in Maine," using the isolation chip (iChi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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