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Toxicology Organizations
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivating proteins, tested in the treatment of leukemia. The word ''toxicology'' () is a neoclas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxicology Research At FDA (NCTR 1193) (6009043040)
Toxicology is a scientific discipline (academia), discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosis, diagnosing and therapy, treating exposures to toxins and toxicants. The dose–response relationship, relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivating proteins, tested ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evidence-based Toxicology
The discipline of evidence-based toxicology (EBT) strives to transparently, consistently, and objectively assess available scientific evidence in order to answer questions in toxicology, the study of the adverse effects of chemical, physical, or biological agents on living organisms and the environment, including the prevention and amelioration of such effects. EBT has the potential to address concerns in the toxicological community about the limitations of current approaches to assessing the state of the science. These include concerns related to transparency in decision making, synthesis of different types of evidence, and the assessment of bias and credibility. Evidence-based toxicology has its roots in the larger movement towards evidence-based practices. By analogy to evidence-based medicine (EBM), the umbrella term evidence-based toxicology (EBT) has been coined to group all approaches intended to better implement the above-mentioned evidence-based principles in toxicology i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorides
Pedanius Dioscorides ( grc-gre, Πεδάνιος Διοσκουρίδης, ; 40–90 AD), “the father of pharmacognosy”, was a Greek physician, pharmacologist, botanist, and author of ''De materia medica'' (, On Medical Material) —a 5-volume Greek encyclopedia about herbal medicine and related medicinal substances (a pharmacopeia), that was widely read for more than 1,500 years. For almost two millennia Dioscorides was regarded as the most prominent writer on plants and plant drugs. Life A native of Anazarbus, Cilicia, Asia Minor, Dioscorides likely studied medicine nearby at the school in Tarsus, which had a pharmacological emphasis, and he dedicated his medical books to Laecanius Arius, a medical practitioner there. Though he writes he lived a "soldier's life" or "soldier-like life", his pharmacopeia refers almost solely to plants found in the Greek-speaking eastern Mediterranean, making it likely that he served in campaigns, or travelled in a civilian capacity, less w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mathieu Joseph Bonaventure Orfila
Mathieu Joseph Bonaventure Orfila (Catalan: ''Mateu Josep Bonaventura Orfila i Rotger'') (24 April 1787 – 12 March 1853) was a Spanish toxicologist and chemist, the founder of the science of toxicology. Role in forensic toxicology If there is reason to believe that a murder or attempted murder may have been committed using poison, a forensic toxicologist is often brought in to examine pieces of evidence such as corpses and food items for poison content. In Orfila's time the primary type of poison in use was arsenic, but there were no reliable ways of testing for its presence. Orfila created new techniques and refined existing techniques in his first treatise, ''Traité des poisons'', greatly enhancing their accuracy. In 1840, Marie Lafarge was tried for the murder of her husband. Although she had had access to arsenic, and arsenic had been found in the victim's food, none could be found in the corpse. Orfila was asked by the court to investigate. He discovered that the te ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
λόγος
''Logos'' (, ; grc, λόγος, lógos, lit=word, discourse, or reason) is a term used in Western philosophy, psychology and rhetoric and refers to the appeal to reason that relies on logic or reason, inductive and deductive reasoning. Aristotle first systemised the usage of the word, making it one of the three principles of rhetoric. This specific use identifies the word closely to the structure and content of text itself. This specific usage has then been developed through the history of western philosophy and rhetoric. The word has also been used in different senses along with ''rhema''. Both Plato and Aristotle used the term ''logos'' along with ''rhema'' to refer to sentences and propositions. It is primarily in this sense the term is also found in religion. Background grc, λόγος, lógos, lit=word, discourse, or reason is related to grc, λέγω, légō, lit=I say, label=Ancient Greek which is cognate with la, Legus, lit=law. The word derives from a Proto-In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ancient Greek
Ancient Greek includes the forms of the Greek language used in ancient Greece and the ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Dark Ages (), the Archaic period (), and the Classical period (). Ancient Greek was the language of Homer and of fifth-century Athenian historians, playwrights, and philosophers. It has contributed many words to English vocabulary and has been a standard subject of study in educational institutions of the Western world since the Renaissance. This article primarily contains information about the Epic and Classical periods of the language. From the Hellenistic period (), Ancient Greek was followed by Koine Greek, which is regarded as a separate historical stage, although its earliest form closely resembles Attic Greek and its latest form approaches Medieval Greek. There were several regional dialects of Ancient Greek, of which Attic Greek developed into Koine. Dia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
-logy
''-logy'' is a suffix in the English language, used with words originally adapted from Ancient Greek ending in ('). The earliest English examples were anglicizations of the French '' -logie'', which was in turn inherited from the Latin '' -logia''. The suffix became productive in English from the 18th century, allowing the formation of new terms with no Latin or Greek precedent. The English suffix has two separate main senses, reflecting two sources of the suffix in Greek: *a combining form used in the names of school or bodies of knowledge, e.g., ''theology'' (loaned from Latin in the 14th century) or ''sociology''. In words of the type ''theology'', the suffix is derived originally from (''-log-'') (a variant of , ''-leg-''), from the Greek verb (''legein'', 'to speak')."-logy." ''The Concise Oxford Dictionary of English Etymology''. Oxford University Press, 1986. retrieved 20 August 2008. The suffix has the sense of "the character or deportment of one who speaks or treat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New Latin
New Latin (also called Neo-Latin or Modern Latin) is the revival of Literary Latin used in original, scholarly, and scientific works since about 1500. Modern scholarly and technical nomenclature, such as in zoological and botanical taxonomy and international scientific vocabulary, draws extensively from New Latin vocabulary, often in the form of classical or neoclassical compounds. New Latin includes extensive new word formation. As a language for full expression in prose or poetry, however, it is often distinguished from its successor, Contemporary Latin. Extent Classicists use the term "Neo-Latin" to describe the Latin that developed in Renaissance Italy as a result of renewed interest in classical civilization in the 14th and 15th centuries. Neo-Latin also describes the use of the Latin language for any purpose, scientific or literary, during and after the Renaissance. The beginning of the period cannot be precisely identified; however, the spread of secular education, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Classical Compound
Neoclassical compounds are compound words composed from combining forms (which act as affixes or stems) derived from classical Latin or ancient Greek roots. New Latin comprises many such words and is a substantial component of the technical and scientific lexicon of English and other languages, via international scientific vocabulary (ISV). For example, '' bio-'' combines with '' -graphy'' to form ''biography'' ("life" + "writing/recording"). Source of international technical vocabulary Neoclassical compounds represent a significant source of Neo-Latin vocabulary. Moreover, since these words are composed from classical languages whose prestige is or was respected throughout the Western European culture, these words typically appear in many different languages. Their widespread use makes technical writing generally accessible to readers who may only have a smattering of the language in which it appears. Not all European languages have been equally receptive to neoclassical tech ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leukemia
Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ''leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia— acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myeloi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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