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Ribosomal Protein Leader
A ribosomal protein leader is a mechanism used in cells to control the cellular concentration of a protein that forms a part of the ribosome, and to make sure that the concentration is neither too high nor too low. Ribosomal protein leaders are RNA sequences that are a part of the 5' UTR of mRNAs encoding a ribosomal protein. When cellular concentrations of the ribosomal protein are high, excess protein will bind to the mRNA leader. This binding event can lower gene expression via a number of mechanisms; for example, in the protein-bound state, the RNA could form an intrinsic transcription termination stem-loop. When cellular concentrations of the ribosomal protein are not high, they are occupied in the ribosome, and are not available in significant quantities to bind the mRNA leader. This leads to increased expression of the gene, which leads to the synthesis of more copies of the ribosomal protein. Many examples of ribosomal protein leaders are known in bacteria, including r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell (biology)
The cell is the basic structural and functional unit of life forms. Every cell consists of a cytoplasm enclosed within a membrane, and contains many biomolecules such as proteins, DNA and RNA, as well as many small molecules of nutrients and metabolites.Cell Movements and the Shaping of the Vertebrate Body in Chapter 21 of Molecular Biology of the Cell '' fourth edition, edited by Bruce Alberts (2002) published by Garland Science. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos. It is also common to describe small molecules such as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
S10 Ribosomal Protein Leader
S10 ribosomal protein leader is a Ribosomal protein leader , ribosomal protein leader involved in the ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of the ribosomal protein S10. Known Examples were predicted in Clostridia or other lineages of Bacillota with bioinformatic approaches. The structure is located in the 5′ untranslated regions of mRNAs encoding ribosomal proteins S10 (rpsJ), L3 (rplc) and L4 (rplD). There is an uncertainty about the ligand, because of a lack of experimental investigation. See also *Ribosomal protein leader References External links Ribosomal protein leader {{molecular-cell-biology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosomal Protein L21 Leader
A ribosomal protein L21 leader is a ribosomal protein leader autoregulatory structure that regulates mRNAs containing a gene that encodes ribosomal protein L21. An RNA motif was predicted to function as an L21 leader in a bioinformatics study, and is found in ''B. subtilis'' and other low-GC Gram-positive bacteria within the phylum Bacillota. It is located in the 5′ untranslated regions of mRNAs encoding ribosomal protein L21, a protein of unknown function, and ribosomal protein L27 (rplU-ysxB-rpmA). See also Ribosomal protein leader A ribosomal protein leader is a mechanism used in cells to control the cellular concentration of a protein that forms a part of the ribosome, and to make sure that the concentration is neither too high nor too low. Ribosomal protein leaders are RNA ... References External links * Ribosomal protein leader {{molecular-cell-biology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosomal Protein L20 Leader
L20 ribosomal protein leader is a ribosomal protein leader involved in the ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of ribosomal proteins L20. The structure is typically located in the 5′ untranslated regions of mRNAs encoding initiation factor 3 followed by ribosomal proteins L35 and L20 (infC-rpmI-rplT), but the regulated mRNAs always contain an L20 gene. A Rho-independent transcription terminator structure that is probably involved in regulation is included at the 3′ end in many examples of L20 ribosomal protein leaders. Three structurally distinct forms of L20 leaders have been experimentally established. One such leader motif occurs in Bacillota and the other two are found in Gammaproteobacteria. Of the latter two, one is found in a wide variety of Gammaproteobacteria, while the other is only reported in ''Escherichia coli''. All three types of leader exhibit apparent similarities to the region of Ribosomal RNA to which ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosomal Protein L19 Leader
L19 Ribosomal protein leaders are part of the ribosome biogenesis. They are used as an autoregulatory mechanism to control the concentration of ribosomal proteins L19, and are located in the 5′ untranslated regions of mRNAs encoding ribosomal protein L19 (rplS). L19 ribosomal protein leaders have been bioinformatically predicted in ''B. subtilis'' and other low-GC Gram-positive bacteria in the phylum Bacillota. More examples that share a similar structure were predicted in Flavobacteria, also using bioinformatic approaches. See also *Ribosomal protein leader References External links * Ribosomal protein leader {{molecular-cell-biology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
S18 Ribosomal Protein Leader
S18 may refer to: Aviation * Forks Airport, in Clallam County, Washington, United States * Letov Š-18, a Czechoslovak biplane trainer * Rans S-18 Stinger II, an American ultralight * Saab 18, a Swedish bomber and reconnaissance aircraft * Sikorsky S-18, a Russian biplane * Spalinger S.18, a Swiss sailplane * Thorp S-18, an American homebuilt aircraft Rail and transit * Forch railway, a line of the Zürich S-Bahn * Ichinoe Station, in Edogawa, Tokyo, Japan * Iyo-Ōzu Station, in Ōzu, Ehime Prefecture, Japan * Naruko Kita Station, in Tempaku-ku, Nagoya, Aichi Prefecture, Japan * Tanimachi Kyūchōme Station, in Ikutamamaemachi, Tennōji-ku, Osaka, Japan * Yoichi Station, in Yoichi, Hokkaido, Japan Vessels * , a submarine of the Royal Navy * , a torpedo boat of the Imperial German Navy * , a submarine of the United States Navy Other uses * 40S ribosomal protein S18 40S ribosomal protein S18 is a protein that in humans is encoded by the ''RPS18'' gene. Ribosomes, the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosomal Protein L13 Leader
L13 ribosomal protein leaders play a role in ribosome biogenesis as part of an autoregulatory mechanism to control the concentration of ribosomal proteins L13. Three structural classes of L13 ribosomal protein leaders were detected by different bioinformatics approaches: in ''B. subtilis'' and other low-GC Gram-positive bacteria., in ''E. coli'' and in Bacteroidia. Although these RNAs are expected to perform the same biological function, they do not appear to be structurally related to one another. The ''E. coli'' example has been experimentally confirmed, though the experiments are not comprehensive. The other two leader structures are thus far not based on experimental support. See also Ribosomal protein leader A ribosomal protein leader is a mechanism used in cells to control the cellular concentration of a protein that forms a part of the ribosome, and to make sure that the concentration is neither too high nor too low. Ribosomal protein leaders are RNA ... Reference ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosomal S15 Leader
S15 Ribosomal protein leaders perform an important regulatory function in ribosome biogenesis. They were used as an autoregulatory mechanism to control the concentration of ribosomal proteins S15. The structure is located in the 5′ untranslated regions of mRNAs encoding ribosomal proteins S15 (rpsO). Multiple distinct structural types of S15 ribosomal protein leaders are known in different organisms. The ''E. coli'' ribosomal S15 leader is an cis-regulatory element, RNA element that can form two alternative Nucleic acid structure, structures found in the ribosomal S15 protein. One of the two alternate structures is a series of three stem-loop, hairpins, the other includes a pseudoknot. This structure causes translational regulation of the S15 protein. Only the final two hairpins are conserved in other species. Another example for Bacteria was predicted in Flavobacteria. The secondary structure of his putative ribosomal leader consists of a hairpin in most species. However, som ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
