Nanoviridae
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Nanoviridae
''Nanoviridae'' is a family of viruses. Plants serve as natural hosts. There are currently 12 species in this family, divided among 2 genera and one unassigned species. Diseases associated with this family include: stunting. Their name is derived from the Greek word νᾶνος (''nanos''; dwarf), because of their small genome and their stunting effect on infected plants. Taxonomy The recognized genera are: * ''Babuvirus'' * ''Nanovirus'' The unassigned species is ''Coconut foliar decay virus''. Virus structure and genome Viruses in the family ''Nanoviridae'' are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-19 nm. The genome is composed of a multiple segments of single stranded circular DNA each ~1 kilobase in length (about 81 kb in total length). There between 6 and 11 circular segments depending on the genus. The segments each encode a single protein. There is a putative stem loop structure in the non-coding region ...
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Nanoviridae
''Nanoviridae'' is a family of viruses. Plants serve as natural hosts. There are currently 12 species in this family, divided among 2 genera and one unassigned species. Diseases associated with this family include: stunting. Their name is derived from the Greek word νᾶνος (''nanos''; dwarf), because of their small genome and their stunting effect on infected plants. Taxonomy The recognized genera are: * ''Babuvirus'' * ''Nanovirus'' The unassigned species is ''Coconut foliar decay virus''. Virus structure and genome Viruses in the family ''Nanoviridae'' are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-19 nm. The genome is composed of a multiple segments of single stranded circular DNA each ~1 kilobase in length (about 81 kb in total length). There between 6 and 11 circular segments depending on the genus. The segments each encode a single protein. There is a putative stem loop structure in the non-coding region ...
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Babuvirus
''Babuvirus'' is a genus of viruses, in the family ''Nanoviridae''. ''Musa'' species serve as natural hosts. There are three species in this genus. Diseases associated with this genus include: stunting, severe necrosis and early plant death. BBTV induces banana bunchy top disease (BBTD). Taxonomy The following species are included in the genus: * ''Abaca bunchy top virus'' * ''Banana bunchy top virus'' * '' Cardamom bushy dwarf virus'' Structure and genome Viruses in the genus ''Babuvirus'' are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-19 nm. Genomes are multipartite Multipartite is a class of virus that have segmented nucleic acid genomes, with each segment of the genome enclosed in a separate viral particle. Only a few ssDNA viruses have multipartite genomes, but a lot more RNA viruses have multipartite geno ... with 6 to 8 circular segments. Genome size is around 81 kb in totsl. Life cycle Viral replicat ...
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Nanovirus
''Nanovirus'' is a genus of viruses, in the family ''Nanoviridae''. Legume plants serve as natural hosts. There are 11 species in this genus. Diseases associated with this genus include: stunting, severe necrosis and early plant death. Taxonomy The following 11 species are assigned to the genus: *''Black medic leaf roll virus'' *''Cow vetch latent virus'' *''Faba bean necrotic stunt virus'' *''Faba bean necrotic yellows virus'' *''Faba bean yellow leaf virus'' *'' Milk vetch dwarf virus'' *'' Parsley severe stunt associated virus'' *'' Pea necrotic yellow dwarf virus'' *'' Pea yellow stunt virus'' *'' Sophora yellow stunt virus'' *''Subterranean clover stunt virus Subterranean(s) or The Subterranean(s) may refer to: * Subterranea (geography), underground structures, both natural and man-made Literature * Subterranean (novel), ''Subterranean'' (novel), a 1998 novel by James Rollins * ''Subterranean Magaz ...'' Structure and genome Virions in the genus ''Nanovirus'' are no ...
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Viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i.e ...
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Coconut Foliar Decay Virus
The coconut tree (''Cocos nucifera'') is a member of the palm tree family (Arecaceae) and the only living species of the genus ''Cocos''. The term "coconut" (or the archaic "cocoanut") can refer to the whole coconut palm, the seed, or the fruit, which botanically is a drupe, not a nut. The name comes from the old Portuguese word '' coco'', meaning "head" or "skull", after the three indentations on the coconut shell that resemble facial features. They are ubiquitous in coastal tropical regions and are a cultural icon of the tropics. The coconut tree provides food, fuel, cosmetics, folk medicine and building materials, among many other uses. The inner flesh of the mature seed, as well as the coconut milk extracted from it, form a regular part of the diets of many people in the tropics and subtropics. Coconuts are distinct from other fruits because their endosperm contains a large quantity of clear liquid, called ''coconut water'' or ''coconut juice''. Mature, ripe coconuts can ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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Retinoblastoma
Retinoblastoma (Rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, the light-detecting tissue of the eye. It is the most common primary malignant intraocular cancer in children, and it is almost exclusively found in young children. Though most children survive this cancer, they may lose their vision in the affected eye(s) or need to have the eye removed. Almost half of children with retinoblastoma have a hereditary genetic defect associated with retinoblastoma. In other cases, it is caused by a congenital mutation in the chromosome 13 gene 13q14 (retinoblastoma protein). Signs and symptoms Retinoblastoma is universally known as the most intrusive intraocular cancer among children. The chance of survival and preservation of the eye depends fully on the severity. Retinoblastoma is extremely rare as there are only about 200 to 300 cases every year in the United States. Looking at retinoblastoma globally, only 1 in about 15,000 children have ...
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Infection
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. ''Mycobacterium tuberculosis'', ...
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Primer (molecular Biology)
Primer may refer to: Arts, entertainment, and media Films * ''Primer'' (film), a 2004 feature film written and directed by Shane Carruth * ''Primer'' (video), a documentary about the funk band Living Colour Literature * Primer (textbook), a textbook used in primary education to teach the alphabet and other basic subjects * Primer (prayer book), a common name for English prayer books used from the 13th to 16th centuries * ''The New England Primer'' (1688), a Puritan book from Colonial America with morality-themed rhymes Music * ''Primer'' (album), a 1995 music album by the musical group Rockapella * Primer 55, an American alternative metal band * "The Primer", a song from the 2005 album ''Alaska'' by Between the Buried and Me Firearms * Primer (firearms), a firearm powder charge-ignition mechanism ** Centerfire ammunition, Boxer or Berdan primers used in modern centerfire cartridges ** Detonator, a small explosive device also known as an explosive primer or blasting cap ** Fr ...
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Polymerases
A polymerase is an enzyme ( EC 2.7.7.6/7/19/48/49) that synthesizes long chains of polymers or nucleic acids. DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, by copying a DNA template strand using base-pairing interactions or RNA by half ladder replication. A DNA polymerase from the thermophilic bacterium, ''Thermus aquaticus'' (''Taq'') ( PDBbr>1BGX EC 2.7.7.7) is used in the polymerase chain reaction, an important technique of molecular biology. A polymerase may be template dependent or template independent. Poly-A-polymerase is an example of template independent polymerase. Terminal deoxynucleotidyl transferase also known to have template independent and template dependent activities. Types By function *DNA polymerase (DNA-directed DNA polymerase, DdDP) **Family A: DNA polymerase I; Pol γ, θ, ν **Family B: DNA polymerase II; Pol α, δ, ε, ζ **Family C: DNA polymerase III holoenzyme **Family X: Pol β, λ, μ * ...
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Transcription (genetics)
Transcription is the process of copying a segment of DNA into RNA. The segments of DNA transcribed into RNA molecules that can encode proteins are said to produce messenger RNA (mRNA). Other segments of DNA are copied into RNA molecules called non-coding RNAs (ncRNAs). mRNA comprises only 1–3% of total RNA samples. Less than 2% of the human genome can be transcribed into mRNA ( Human genome#Coding vs. noncoding DNA), while at least 80% of mammalian genomic DNA can be actively transcribed (in one or more types of cells), with the majority of this 80% considered to be ncRNA. Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. Transcription proceeds in the following general steps: # RNA polymerase, together with one or more general transcription factors, binds to promoter DNA ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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