Laboratory Rats
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Laboratory Rats
A laboratory rat or lab rat is a brown rat of the subspecies '' Rattus norvegicus domestica'' which is bred and kept for scientific research. While less commonly used for research than mice (see laboratory mouse), rats have served as an important animal model for research in psychology and biomedical science. Origins In 18th century Europe, wild brown rats ran rampant and this infestation fueled the industry of rat-catching. Rat-catchers would not only make money by trapping the rodents, but also by selling them for food or, more commonly, for rat-baiting. Rat-baiting was a popular sport, which involved filling a pit with rats and timing how long it took for a terrier to kill them all. Over time, breeding the rats for these contests may have produced variations in color, notably the albino and hooded varieties. The first time one of these albino mutants was brought into a laboratory for a study was in 1828 for an experiment on fasting. Over the next 30 years, rats were u ...
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Albino Rat
Albinism is the congenital absence of melanin in an animal or plant resulting in white hair, feathers, scales and skin and pink or blue eyes. Individuals with the condition are referred to as albino. Varied use and interpretation of the terms mean that written reports of albinistic animals can be difficult to verify. Albinism can reduce the survivability of an animal; for example, it has been suggested that albino alligators have an average survival span of only 24 hours due to the lack of protection from UV radiation and their lack of camouflage to avoid predators. It is a common misconception that all albino animals have characteristic pink or red eyes (resulting from the lack of pigment in the iris allowing the blood vessels of the retina to be visible), however this is not the case for some forms of albinism. Familiar albino animals include in-bred strains of laboratory animals (rats, mice and rabbits), but populations of naturally occurring albino animals exist in the wil ...
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Kyoto University
, mottoeng = Freedom of academic culture , established = , type = National university, Public (National) , endowment = ¥ 316 billion (2.4 1000000000 (number), billion USD) , faculty = 3,480 (Teaching Staff) , administrative_staff = 3,978 (Total Staff) , students = 22,615 , president = Nagahiro Minato , city = Kyoto , state = Kyoto Prefecture, Kyoto , country = Japan , coor = , undergrad = 13,038 , postgrad = 9,308 , campus = Urban area, Urban,, , colors = Dark blue (color), Dark blue , nickname = Kyodai , mascot = None , free_label = Athletics , free = 48 varsity teams , affiliations = Kansai Big Six, Association of Southeast Asian Institutions of Higher Learning, ASAIHL , logo = , website www.kyoto-u.ac.jp , or , is a public university, public research university located in Kyoto, Japan. Founded in 1897, it is one of the former Imperial Universities and the second oldest university in Japan. KyotoU is consistent ...
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Bussey Institution
The Bussey Institute (1883–1936) was a respected biological institute at Harvard University. It was named for Benjamin Bussey, who, in 1835, endowed the establishment of an undergraduate school of agriculture and horticulture and donated land in Jamaica Plain, Massachusetts that became the Arnold Arboretum. Bussey, a silversmith, had bought the land from the Weld family in 1806, and built a mansion in 1815. When he died, he left to Harvard. By 1871 the Bussey Institute had been built. Notable alumni James Drummond Dole obtained a bachelor in agriculture at the Bussey Institute before moving to Hawaii and developing pineapple production and the canning industry there. Alfred Kinsey, an American biologist who became famous for his work on human sexuality, studied at the Bussey Institute under famed entomologist William Morton Wheeler. Edward Murray East Edward Murray East (October 4, 1879 – November 9, 1938) was an American plant geneticist, botanist, agronomist and e ...
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William Ernest Castle
William Ernest Castle (October 25, 1867 – June 3, 1962) was an early American geneticist. Early years William Ernest Castle was born on a farm in Ohio and took an early interest in natural history. He graduated in 1889 from Denison University in Granville, Ohio, a Baptist college that emphasized classics, and went on to become a teacher of Latin at Ottawa University in Ottawa, Kansas, where he published his first paper on the flowering plants of the area. After three years of teaching, botany won out over Latin.http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/castle-william-e.pdf Education Castle entered the senior class of Harvard University in 1892 and in 1893 took a second A.B. degree with honors. He was appointed laboratory assistant in zoology, an A.M. degree in 1894 and a Ph.D. in 1895. He then taught zoology at the University of Wisconsin–Madison and at the Knox College in Galesburg, Illinois, each for a year. Harvard and Drosophila Castl ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ...
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University Of California Press
The University of California Press, otherwise known as UC Press, is a publishing house associated with the University of California that engages in academic publishing. It was founded in 1893 to publish scholarly and scientific works by faculty of the University of California, established 25 years earlier in 1868, and has been officially headquartered at the university's flagship campus in Berkeley, California, since its inception. As the non-profit publishing arm of the University of California system, the UC Press is fully subsidized by the university and the State of California. A third of its authors are faculty members of the university. The press publishes over 250 new books and almost four dozen multi-issue journals annually, in the humanities, social sciences, and natural sciences, and maintains approximately 4,000 book titles in print. It is also the digital publisher of Collabra and Luminos open access (OA) initiatives. The University of California Press publishes in ...
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Herbert McLean Evans
Herbert McLean Evans (September 23, 1882 – March 6, 1971) was an American anatomist and embryologist best known for co-discovering Vitamin E. Education He was born in Modesto, California. In 1908, he obtained his medical degree from Johns Hopkins University. Career Evans became associate professor of anatomy at Johns Hopkins University. Evans moved back to California in 1915 and was made professor of anatomy at the University of California, Berkeley, and held that position until his death. His medical research at Berkeley addressed problems relating to human nutrition, endocrinology, embryology, and histology. In 1918, his research into the number of human chromosomes led him to believe the number to be 48, when most people assumed the number to be much higher. It was only later discovered that the correct figure was 46. Evans had much greater success however with hormones extracted from the anterior lobe of the pituitary gland. He isolated Human Growth Hormone, which is ess ...
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University Of California, Berkeley
The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant university and the founding campus of the University of California system. Its fourteen colleges and schools offer over 350 degree programs and enroll some 31,800 undergraduate and 13,200 graduate students. Berkeley ranks among the world's top universities. A founding member of the Association of American Universities, Berkeley hosts many leading research institutes dedicated to science, engineering, and mathematics. The university founded and maintains close relationships with three national laboratories at Berkeley, Livermore and Los Alamos, and has played a prominent role in many scientific advances, from the Manhattan Project and the discovery of 16 chemical elements to breakthroughs in computer science and genomics. Berkeley is ...
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Reproduction
Reproduction (or procreation or breeding) is the biological process by which new individual organisms – "offspring" – are produced from their "parent" or parents. Reproduction is a fundamental feature of all known life; each individual organism exists as the result of reproduction. There are two forms of reproduction: asexual and sexual. In asexual reproduction, an organism can reproduce without the involvement of another organism. Asexual reproduction is not limited to single-celled organisms. The cloning of an organism is a form of asexual reproduction. By asexual reproduction, an organism creates a genetically similar or identical copy of itself. The evolution of sexual reproduction is a major puzzle for biologists. The two-fold cost of sexual reproduction is that only 50% of organisms reproduce and organisms only pass on 50% of their genes.John Maynard Smith ''The Evolution of Sex'' 1978. Sexual reproduction typically requires the sexual interaction of two specializ ...
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Protein (nutrient)
Proteins are essential nutrients for the human body. They are one of the building blocks of body tissue and can also serve as a fuel source. As a fuel, proteins provide as much energy density as carbohydrates: 4 kcal (17 kJ) per gram; in contrast, lipids provide 9 kcal (37 kJ) per gram. The most important aspect and defining characteristic of protein from a nutritional standpoint is its amino acid composition. Proteins are polymer chains made of amino acids linked together by peptide bonds. During human digestion, proteins are broken down in the stomach to smaller polypeptide chains via hydrochloric acid and protease actions. This is crucial for the absorption of the essential amino acids that cannot be biosynthesized by the body. There are nine essential amino acids which humans must obtain from their diet in order to prevent protein–energy malnutrition and resulting death. They are phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, an ...
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Lafayette Mendel
Lafayette Benedict Mendel (February 5, 1872 – December 9, 1935) was an American biochemist known for his work in nutrition, with longtime collaborator Thomas B. Osborne, including the study of Vitamin A, Vitamin B, lysine and tryptophan. Life Mendel was born in Delhi, New York, son of Benedict Mendel, a merchant born in Aufhausen, Germany in 1833, and Pauline Ullman, born in Eschenau, Germany. His father immigrated to the United States from Germany in 1851, his mother in 1870."Lafayette Benedict Mendel."
World of Biology. Farmington Hills, Mich.: Thomson Gale. 2006.
At 15, he won a New York State scholarship. Mendel studied classics, economics and the humanities, as well as biology and chemistry at

Thomas Burr Osborne (chemist)
Thomas Burr Osborne (August 5, 1859 – January 29, 1929) was a biochemist who, with Lafayette Mendel, independently discovered Vitamin A, though Elmer McCollum and Marguerite Davis were ultimately given credit, as they had submitted their paper first by three weeks. He is known for his work isolating and characterizing seed proteins, and for determining protein nutritional requirements. His career was spent at the Connecticut Agricultural Experiment Station. Biography Thomas Burr Osborne was born in New Haven, Connecticut on August 5, 1859. He was the son of lawyer Arthur Dimon Osborne and the grandson of US Representative Thomas Burr Osborne. He earned an undergraduate degree from Yale College in 1881, and a PhD in chemistry there in 1885. He married Elizabeth Annah Johnson on June 23, 1886, and they had one son. Osborne died at his home in New Haven on January 29, 1929. Career His life exhibited "a single purpose, the understanding of the relationships of proteins to eac ...
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