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Harvard Medical School
Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the United States. It provides patient care, medical education, and research training through its 15 clinical affiliates and research institutes, including Massachusetts General Hospital (MGH), Boston Children's Hospital, Dana–Farber Cancer Institute, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Mount Auburn Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, Spaulding Rehabilitation Hospital, and others. Harvard Medical School also partners with newer entities such as Harvard Catalyst, Broad Institute , Broad Institute of MIT and Harvard, Harvard Stem Cell Institute, the Center for Primary Care, and Wyss Institute for Biologically Inspired Engineering. History Harvard ...
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Boston
Boston is the capital and most populous city in the Commonwealth (U.S. state), Commonwealth of Massachusetts in the United States. The city serves as the cultural and Financial centre, financial center of New England, a region of the Northeastern United States. It has an area of and a population of 675,647 as of the 2020 United States census, 2020 census, making it the third-largest city in the Northeastern United States after New York City and Philadelphia. The larger Greater Boston metropolitan statistical area has a population of 4.9 million as of 2023, making it the largest metropolitan area in New England and the Metropolitan statistical area, eleventh-largest in the United States. Boston was founded on Shawmut Peninsula in 1630 by English Puritans, Puritan settlers, who named the city after the market town of Boston, Lincolnshire in England. During the American Revolution and American Revolutionary War, Revolutionary War, Boston was home to several seminal events, incl ...
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Heraldry Of Harvard University
Harvard University adopted an official seal (emblem), seal soon after it was founded in 1636 and named "Harvard College" in 1638; a variant is still used. Each school within the university (Harvard College, Harvard Medical School, Harvard Law School, Harvard Extension School, Harvard Graduate School of Arts and Sciences, etc.) has its own distinctive Escutcheon (heraldry), shield as well, as do many other internal administrative units such as the Harvard College residential "Houses" and the Harvard Library. Many extracurricular organizationssuch as clubs, societies, and athletic teamsalso have their own shield, often based on the coat of arms of Harvard itself. Harvard University coat of arms Description The Harvard University coat of arms, or escutcheon (heraldry), shield, has a field of the color 'Harvard Crimson'. In the foreground are three open books with the word (Latin for 'truth') inscribed across them. History The Harvard Board of Overseers originally design ...
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Spaulding Rehabilitation Hospital
The Spaulding Rehabilitation Hospital is a 132-bed rehabilitation teaching hospital located in Boston, Massachusetts. It is the official teaching hospital for Harvard Medical School’s Department of Physical Medicine and Rehabilitation and the main campus of the Spaulding Rehabilitation Network. The hospital is a member of Partners Continuing Care under Mass General Brigham, a non-profit organization that owns several hospitals in Massachusetts. Reputation Spaulding Rehabilitation Hospital has been the only hospital in New England to be continuously ranked by the '' U.S. News & World Report'' in its Best Hospitals Survey since 1995. In 2018, the hospital was ranked #2. History Spaulding Rehabilitation Hospital was founded in 1971 as the Massachusetts Rehabilitation Hospital. It was named after Josiah Spaulding, a founder, after his death in 1983. The former location was in the West End of Boston, located behind North Station at 125 Nashua Street. Redevelopment Its new 300,0 ...
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Coenzyme A
Coenzyme A (CoA, SHCoA, CoASH) is a coenzyme, notable for its role in the Fatty acid metabolism#Synthesis, synthesis and Fatty acid metabolism#.CE.B2-Oxidation, oxidation of fatty acids, and the oxidation of pyruvic acid, pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a Substrate (chemistry), substrate, and around 4% of cellular enzymes use it (or a thioester) as a substrate. In humans, CoA biosynthesis requires cysteine, pantothenic acid, pantothenate (vitamin B5), and adenosine triphosphate (ATP). In acetyl-CoA, its acetyl form, coenzyme A is a highly versatile molecule, serving metabolic functions in both the Anabolism, anabolic and Catabolism, catabolic pathways. Acetyl-CoA is utilised in the post-translational regulation and allosteric regulation of pyruvate dehydrogenase and carboxylase to maintain and support the partition of Pyruvic acid, pyruvate synthesis and degradation. Discovery of structure Coenzyme A was ident ...
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Vitamin B12
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. One of eight B vitamins, it serves as a vital cofactor (biochemistry), cofactor in DNA synthesis and both fatty acid metabolism, fatty acid and amino acid metabolism. It plays an essential role in the nervous system by supporting myelinogenesis, myelin synthesis and is critical for the maturation of red blood cells in the bone marrow. While animals require B12, plants do not, relying instead on alternative enzymatic pathways. Vitamin B12 is the most chemically complex of all vitamins, and is synthesized exclusively by certain archaea and bacteria. Natural food sources include meat, shellfish, liver, fish, poultry, Egg as food, eggs, and dairy products. It is also added to many breakfast cereals through food fortification and is available in dietary supplement and pharmaceutical forms. Supplements are commonly taken orally but may be administered via intramuscular injection to treat defic ...
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Diabetes Mellitus
Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained hyperglycemia, high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of the body becoming unresponsive to insulin's effects. Classic symptoms include polydipsia (excessive thirst), polyuria (excessive urination), polyphagia (excessive hunger), Weight loss#Unintentional, weight loss, and blurred vision. If left untreated, the disease can lead to various health complications, including disorders of the Cardiovascular disease, cardiovascular system, Diabetic retinopathy, eye, Diabetic nephropathy, kidney, and Diabetic neuropathy, nerves. Diabetes accounts for approximately 4.2 million deaths every year, with an estimated 1.5 million caused by either untreated or poorly treated diabetes. The major types of diabetes are Type 1 diabetes, type 1 and Type 2 diabetes, type 2. The most common treatment for ty ...
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Charles William Eliot
Charles William Eliot (March 20, 1834 – August 22, 1926) was an American academic who was president of Harvard University from 1869 to 1909, the longest term of any Harvard president. A member of the prominent Eliot family (America), Eliot family of Boston, he transformed Harvard from a respected provincial college into America's preeminent research university. Theodore Roosevelt called him "the only man in the world I envy." Early life and education Eliot was born a scion of the wealthy Eliot family (America), Eliot family of Boston. He was the son of politician Samuel Atkins Eliot (politician), Samuel Atkins Eliot and his wife Mary (née Lyman), and was the grandchild of banker Samuel Eliot (banker), Samuel Eliot and merchant Theodore Lyman of the Lyman Estate. His grandfather was one of the wealthiest merchants of Boston. He was one of five siblings and the only boy. Eliot graduated from Boston Latin School in 1849 and from Harvard University in 1853. He was later made an ho ...
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Holden Chapel
Holden Chapel is a small building in Harvard Yard on the campus of Harvard University. Completed in 1744, it is the third oldest building at Harvard and one of the oldest college buildings in America. Early history In December 1741, Mrs. Samuel Holden, the widow of a former Governor of the Bank of England, offered Harvard a 400 pound sterling donation towards the construction of a chapel on campus, prompted by a suggestion from Thomas Hutchinson (governor), Thomas Hutchinson. After additional funds were raised, the chapel opened in March 1745. From 1744 to 1772 (except for 1767–68) the chapel housed morning and evening prayers for the Harvard student body, as well as providing space for some secular uses such as lectures. After the 1783 establishment of the Harvard Medical School, the building was used by its founder, John Warren (surgeon, born 1753), John Warren, on a regular basis for 19 years, and intermittently by him and others thereafter until 1825. 20th/21st century I ...
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Harvard Hall
Harvard Hall is a Harvard University classroom building in Harvard Yard, Cambridge, Massachusetts. First Harvard Hall The present Harvard Hall replaces an earlier structure of the same name on the same site. The first Harvard Hall was built between 1674 and 1677. It was Harvard College's first brick building and replaced a decaying wooden building located a few hundred feet to the southeast. Samuel Andrew, a local Cambridge merchant and shipwright, was the master builder. Present Building The original Harvard Hall burned on January 24, 1764, destroying 4,500 of the College Library's 5,000 books as well as its collection of "philosophical apparatus" (scientific instruments). The Massachusetts General Court, which had been meeting in Harvard Hall to escape a smallpox epidemic in Boston, took responsibility for the fire and funded reconstruction. Thanks to generous donors such as Thomas Hollis V and John Hancock, within two years the new Harvard Hall housed a library larger th ...
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Columbia University College Of Physicians And Surgeons
The Columbia University College of Physicians and Surgeons (officially known as Columbia University Roy and Diana Vagelos College of Physicians and Surgeons) is the medical school of Columbia University, located at the Columbia University Irving Medical Center in the Washington Heights neighborhood of Manhattan. Founded in 1767 by Samuel Bard as the medical department of King's College (now Columbia University), the College of Physicians and Surgeons was the first medical school in the Thirteen Colonies to award the Doctor of Medicine (MD) degree. Beginning in 1993, the College of Physicians and Surgeons was also the first U.S. medical school to hold a white coat ceremony. Following a gift of $250 million from Roy and Diana Vagelos in 2017, the school became the first medical school in the nation to replace loans with scholarships for all students who qualify for financial aid when it did so in 2018. Columbia is affiliated with NewYork-Presbyterian Hospital. Students addit ...
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Perelman School Of Medicine At The University Of Pennsylvania
The Perelman School of Medicine (commonly known as Penn Med) is the medical school of the University of Pennsylvania, a Private university, private, Ivy League research university located in Philadelphia. Founded in 1765, the Perelman School of Medicine is the List of medical schools in the United States, oldest medical school in the United States. Today, the Perelman School of Medicine is a major center of biomedical research and education with over 2,900 faculty members and nearly $1 billion in annual sponsored program awards. History 18th century The founding of a school of medicine was proposed by John Morgan (physician), John Morgan, a graduate of the Academy and College of Philadelphia, College of Philadelphia and the University of Edinburgh Medical School. After training in Edinburgh and other European cities, Morgan returned to Philadelphia in 1765. With fellow University of Edinburgh Medical School graduate William Shippen Jr., Morgan persuaded the college's trustees ...
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Benjamin Waterhouse
Benjamin Waterhouse (March 4, 1754 – October 2, 1846) was a physician, co-founder and professor of Harvard Medical School. He is most well known for being the first doctor to test the smallpox vaccine in the United States, which he carried out on his own family. Biography Early life Waterhouse was born into a Quakers, Quaker family, although he never adopted the religion as his own. His parents were Timothy Waterhouse, a chair maker who also served on the Governor's Council, and Hannah Waterhouse. Born and raised in Rhode Island, his medical career began at age 16, when he apprenticed for a doctor in his hometown. At age 21, he left the United States to study medicine in Europe at several notable institutions, such as with Dr. John Fothergill (physician), John Fothergill in London, England. He was also educated in Edinburgh at the University of Edinburgh Medical School. He matriculated on October 28, 1778, at Leiden University in The Netherlands and received at the same Univ ...
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