Dendroaspis
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Dendroaspis
Mambas are fast moving highly venomous snakes of the genus ''Dendroaspis'' (which literally means "tree asp") in the family Elapidae. Four extant species are recognised currently; three of those four species are essentially arboreal and green in colour, whereas the black mamba, ''Dendroaspis polylepis'', is largely terrestrial and generally brown or grey in colour. All are native to various regions in sub-Saharan Africa and all are feared throughout their ranges, especially the black mamba. In Africa there are many legends and stories about mambas. also at/ref> Behaviour The three green species of mambas are arboreal, whereas the black mamba is largely terrestrial. The black mamba is one of the largest and most venomous snakes in Africa. All four species are active diurnal hunters, preying on birds, lizards, and small mammals. At nightfall some species, especially the terrestrial black mamba, shelter in a lair. A mamba may retain the same lair for years. Mambas and cob ...
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Eastern Green Mamba
The eastern green mamba (''Dendroaspis angusticeps'') is a highly venomous snake species of the mamba genus ''Dendroaspis'' native to the coastal regions of southern East Africa. Described by Scottish surgeon and zoologist Andrew Smith in 1849, it has a slender build with a bright green back and green-yellow ventral scales. Adult females average around in length, and males are slightly smaller. A shy and elusive species, the eastern green mamba is rarely seen. This elusiveness is usually attributed to its arboreal habitat and green colouration, which acts as camouflage in its natural environment. It has also been observed to use ambush predation, like many vipers, contrary to the active foraging style typical of other elapid snakes. It preys on birds, eggs, bats, and rodents such as mice, rats, and gerbils. Its venom consists of both neurotoxins and cardiotoxins. Symptoms of envenomation include swelling of the injection site, dizziness, and nausea, accompanied by difficult ...
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Dendroaspis Angusticeps
The eastern green mamba (''Dendroaspis angusticeps'') is a highly venomous snake species of the mamba genus ''Dendroaspis'' native to the coastal regions of southern East Africa. Described by Scottish surgeon and zoologist Andrew Smith in 1849, it has a slender build with a bright green back and green-yellow ventral scales. Adult females average around in length, and males are slightly smaller. A shy and elusive species, the eastern green mamba is rarely seen. This elusiveness is usually attributed to its arboreal habitat and green colouration, which acts as camouflage in its natural environment. It has also been observed to use ambush predation, like many vipers, contrary to the active foraging style typical of other elapid snakes. It preys on birds, eggs, bats, and rodents such as mice, rats, and gerbils. Its venom consists of both neurotoxins and cardiotoxins. Symptoms of envenomation include swelling of the injection site, dizziness, and nausea, accompanied by difficul ...
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Black Mamba
The black mamba (''Dendroaspis polylepis'') is a species of highly venomous snake belonging to the family Elapidae. It is native to parts of sub-Saharan Africa. First formally described by Albert Günther in 1864, it is the second-longest venomous snake after the king cobra; mature specimens generally exceed and commonly grow to . Specimens of have been reported. Its skin colour varies from grey to dark brown. Juvenile black mambas tend to be paler than adults and darken with age. The species is both terrestrial (ground-living) and arboreal (tree-living); it inhabits savannah, woodland, rocky slopes and in some regions, dense forest. It is diurnal and is known to prey on birds and small mammals. Over suitable surfaces, it can move at speeds up to for short distances. Adult black mambas have few natural predators. In a threat display, the black mamba usually opens its inky-black mouth, spreads its narrow neck-flap and sometimes hisses. It is capable of striking at con ...
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Black Mamba
The black mamba (''Dendroaspis polylepis'') is a species of highly venomous snake belonging to the family Elapidae. It is native to parts of sub-Saharan Africa. First formally described by Albert Günther in 1864, it is the second-longest venomous snake after the king cobra; mature specimens generally exceed and commonly grow to . Specimens of have been reported. Its skin colour varies from grey to dark brown. Juvenile black mambas tend to be paler than adults and darken with age. The species is both terrestrial (ground-living) and arboreal (tree-living); it inhabits savannah, woodland, rocky slopes and in some regions, dense forest. It is diurnal and is known to prey on birds and small mammals. Over suitable surfaces, it can move at speeds up to for short distances. Adult black mambas have few natural predators. In a threat display, the black mamba usually opens its inky-black mouth, spreads its narrow neck-flap and sometimes hisses. It is capable of striking at con ...
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Dendroaspis Polylepis
The black mamba (''Dendroaspis polylepis'') is a species of highly venomous snake belonging to the family Elapidae. It is native to parts of sub-Saharan Africa. First formally described by Albert Günther in 1864, it is the second-longest venomous snake after the king cobra; mature specimens generally exceed and commonly grow to . Specimens of have been reported. Its skin colour varies from grey to dark brown. Juvenile black mambas tend to be paler than adults and darken with age. The species is both terrestrial (ground-living) and arboreal (tree-living); it inhabits savannah, woodland, rocky slopes and in some regions, dense forest. It is diurnal and is known to prey on birds and small mammals. Over suitable surfaces, it can move at speeds up to for short distances. Adult black mambas have few natural predators. In a threat display, the black mamba usually opens its inky-black mouth, spreads its narrow neck-flap and sometimes hisses. It is capable of striking at consi ...
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Dendroaspis Polylepis Striking
Mambas are fast moving highly venomous snakes of the genus ''Dendroaspis'' (which literally means "tree asp") in the family Elapidae. Four extant species are recognised currently; three of those four species are essentially arboreal and green in colour, whereas the black mamba, ''Dendroaspis polylepis'', is largely terrestrial and generally brown or grey in colour. All are native to various regions in sub-Saharan Africa and all are feared throughout their ranges, especially the black mamba. In Africa there are many legends and stories about mambas. also at/ref> Behaviour The three green species of mambas are arboreal, whereas the black mamba is largely terrestrial. The black mamba is one of the largest and most venomous snakes in Africa. All four species are active diurnal hunters, preying on birds, lizards, and small mammals. At nightfall some species, especially the terrestrial black mamba, shelter in a lair. A mamba may retain the same lair for years. Mambas and cobras ar ...
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Dendroaspis Jamesoni
Jameson's mamba (''Dendroaspis jamesoni'') is a species of highly venomous snake native to equatorial Africa. A member of the mamba genus, ''Dendroaspis'', it is slender with dull green upper parts and cream underparts and generally ranges from in length. Described by Scottish naturalist Thomas Traill in 1843, it has two recognised subspecies: the nominate subspecies from central and west sub-Saharan Africa and the eastern black-tailed subspecies from eastern sub-Saharan Africa, mainly western Kenya. Predominantly arboreal, Jameson's mamba preys mainly on birds and mammals. Its venom consists of both neurotoxins and cardiotoxins. Symptoms of envenomation in humans include pain and swelling at the bite site, followed by swelling, chills, sweating, abdominal pain and vomiting, with subsequent slurred speech, difficulty breathing and paralysis. Fatalities have been recorded within three to four hours of being bitten. The venom of the eastern subspecies is around twice as potent as ...
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Dendroaspis Viridis
The western green mamba (''Dendroaspis viridis'') is a long, thin, and highly venomous snake species of the mamba genus, ''Dendroaspis''. This species was first described in 1844 by American herpetologist Edward Hallowell. The western green mamba is a fairly large and predominantly arboreal species, capable of navigating through trees swiftly and gracefully. It will also descend to ground level to pursue prey such as rodents and other small mammals. The western green mamba is a shy and agile snake that lives mainly in the coastal tropical rainforest, thicket, and woodland regions of western Africa. Its venom is a highly potent mixture of rapid-acting presynaptic and postsynaptic neurotoxins (dendrotoxins), cardiotoxins and fasciculins. Some consider this species not to be a particularly aggressive snake, but others have suggested that they are extremely nervous and are prone to attack aggressively when cornered. Conflict with humans is low compared to some other species found in ...
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Antivenom
Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. The specific antivenom needed depends on the species involved. It is given by injection. Side effects may be severe. They include serum sickness, shortness of breath, and allergic reactions including anaphylaxis. Antivenom is traditionally made by collecting venom from the relevant animal and injecting small amounts of it into a domestic animal. The antibodies that form are then collected from the domestic animal's blood and purified. Versions are available for spider bites, snake bites, fish stings, and scorpion stings. Due to the high cost of producing antibody-based antivenoms and their short shelf lives when not refrigerated, alternative methods of production of antivenoms ar ...
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Calciseptine
Calciseptine (CaS) is a natural neurotoxin isolated from the black mamba ''Dendroaspis p. polylepis'' venom. This toxin consists of 60 amino acids with four disulfide bonds. Calciseptine specifically blocks L-type calcium channels, but not other voltage-dependent Ca2+ channels such as N-type and T-type channels. History The black mamba (''Dendroaspis polylepis'') is generally considered to be one of the deadliest snakes on the planet, and is responsible for many fatalities throughout its sub-Saharan Africa range. Without treatment, the bite of a Black Mamba causes a 100% mortality rate. The venom of the Black Mamba consists of more than 28 peptides. One of these peptides is calciseptine. It makes up 2.8% of the venom of the Black Mamba. When first purified, the peptide was called protein E3, which was later changed to calciseptine by Weille et al. Importance Calciseptine has been shown to specifically inhibit the L-type voltage-gated Ca2+ channels and was the first natural polype ...
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Dendrotoxin
Dendrotoxins are a class of presynaptic neurotoxins produced by mamba snakes (''Dendroaspis'') that block particular subtypes of voltage-gated potassium channels in neurons, thereby enhancing the release of acetylcholine at neuromuscular junctions. Because of their high potency and selectivity for potassium channels, dendrotoxins have proven to be extremely useful as pharmacological tools for studying the structure and function of these ion channel proteins. Functional effects in the nervous system Dendrotoxins have been shown to block particular subtypes of voltage-gated potassium (K+) channels in neuronal tissue. In the nervous system, voltage-gated K+ channels control the excitability of nerves and muscles by controlling the resting membrane potential and by repolarizing the membrane during action potentials. Dendrotoxin has been shown to bind the nodes of Ranvier of motor neurons and to block the activity of these potassium channels. In this way, dendrotoxins prolong the ...
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Elapidae
Elapidae (, commonly known as elapids ; grc, ἔλλοψ ''éllops'' "sea-fish") is a family of snakes characterized by their permanently erect fangs at the front of the mouth. Most elapids are venomous, with the exception of the genus Emydocephalus. Many members of this family exhibit a threat display of rearing upwards while spreading out a neck flap. Elapids are endemic to tropical and subtropical regions around the world, with terrestrial forms in Asia, Australia, Africa, and the Americas and marine forms in the Pacific and Indian Oceans. Members of the family have a wide range of sizes, from the white-lipped snake to the king cobra. Most species have neurotoxic venom which is channeled by their hollow fangs, and some may contain other toxic components in various proportions. The family includes 55 genera with some 360 species and over 170 subspecies. Description Terrestrial elapids look similar to the Colubridae; almost all have long, slender bodies with smooth scales, a ...
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