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Current Of Injury
The current of injury – also known as the ''demarcation current,'' ''hermann's demarcation current'' or ''injury potential'' – is the electric current from the central part of the body to an injured nerve or muscle, or to another injured excitable tissue. The injured tissue has a negative voltage compared to the central part of the body. History The concept originates from the research of Carlo Matteucci and Emil du Bois-Reymond in the mid-19th century. It has later occasionally been used in physiology textbooks, but is now mostly used in connection with heart damages (as listed in e.g. the index of Guyton's ''Textbook of Medical Physiology''). Such manifestations in the heart may be seen in the electrocardiogram as Osborn waves. It has been found by Elmer J. Lund that establishing an artificial electrical field causing a current mimicking the current of injury could facilitate regeneration. This potential for a regeneration therapy was further studied by Robert O. Beck ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electric Current
An electric current is a stream of charged particles, such as electrons or ions, moving through an electrical conductor or space. It is measured as the net rate of flow of electric charge through a surface or into a control volume. The moving particles are called charge carriers, which may be one of several types of particles, depending on the conductor. In electric circuits the charge carriers are often electrons moving through a wire. In semiconductors they can be electrons or holes. In an electrolyte the charge carriers are ions, while in plasma, an ionized gas, they are ions and electrons. The SI unit of electric current is the ampere, or ''amp'', which is the flow of electric charge across a surface at the rate of one coulomb per second. The ampere (symbol: A) is an SI base unit. Electric current is measured using a device called an ammeter. Electric currents create magnetic fields, which are used in motors, generators, inductors, and transformers. In ordinary con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elmer J
Elmer is a name of Germanic British origin. The given name originated as a surname, a medieval variant of the given name Aylmer, derived from Old English ''æþel'' (noble) and ''mær'' (famous). It was adopted as a given name in the United States, "in honor of the popularity of the brothers Ebenezer and Jonathan Elmer, leading supporters of the American Revolution." The name has declined in popularity since the first decades of the 20th century and fell out of the top 1,000 names used for American boys in 2009. However, it continues in use for newborn boys in the United States, where 154 boys born there in 2021 received the name. The name is common in the United States and Canada. Notable people with the name include: Mononym * Eilmer of Malmesbury (or Elmer), 11th-century English Benedictine monk * In the amateur radio subculture, an ''Elmer'' is a mentor to a newcoming amateur radio operatorThe term first appeared in the March, 1971 issue of ''QST'' magazine's "How's DX" c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myelin Sheath
Myelin is a lipid-rich material that surrounds nerve cell axons (the nervous system's "wires") to insulate them and increase the rate at which electrical impulses (called action potentials) are passed along the axon. The myelinated axon can be likened to an electrical wire (the axon) with insulating material (myelin) around it. However, unlike the plastic covering on an electrical wire, myelin does not form a single long sheath over the entire length of the axon. Rather, myelin sheaths the nerve in segments: in general, each axon is encased with multiple long myelinated sections with short gaps in between called nodes of Ranvier. Myelin is formed in the central nervous system (CNS; brain, spinal cord and optic nerve) by glial cells called oligodendrocytes and in the peripheral nervous system (PNS) by glial cells called Schwann cells. In the CNS, axons carry electrical signals from one nerve cell body to another. In the PNS, axons carry signals to muscles and glands or from sensor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Perineurium
The perineurium is a protective sheath that surrounds a nerve fascicle. This bundles together axons targeting the same anatomical location. The perineurium is composed from fibroblasts. In the peripheral nervous system, the myelin sheath of each axon in a nerve is wrapped in a delicate protective sheath known as the endoneurium. Fascicles, bundles of neurons, are surrounded by the perineurium. Several fascicles may be in turn bundled together with a blood supply and fatty tissue within yet another sheath, the epineurium. This grouping structure is analogous to the muscular organization system of epimysium, perimysium and endomysium. Structure The perineurium is composed of connective tissue, which has a distinctly lamellar arrangement consisting of one to several concentric layers. The perineurium is composed of perineurial cells, which are epithelioid myofibroblasts. Perineurial cells are sometimes referred to as myoepithelioid due to their epithelioid and myofibroblastoid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert O
The name Robert is an ancient Germanic given name, from Proto-Germanic "fame" and "bright" (''Hrōþiberhtaz''). Compare Old Dutch ''Robrecht'' and Old High German ''Hrodebert'' (a compound of '' Hruod'' ( non, Hróðr) "fame, glory, honour, praise, renown" and ''berht'' "bright, light, shining"). It is the second most frequently used given name of ancient Germanic origin. It is also in use as a surname. Another commonly used form of the name is Rupert. After becoming widely used in Continental Europe it entered England in its Old French form ''Robert'', where an Old English cognate form (''Hrēodbēorht'', ''Hrodberht'', ''Hrēodbēorð'', ''Hrœdbœrð'', ''Hrœdberð'', ''Hrōðberχtŕ'') had existed before the Norman Conquest. The feminine version is Roberta. The Italian, Portuguese, and Spanish form is Roberto. Robert is also a common name in many Germanic languages, including English, German, Dutch, Norwegian, Swedish, Scots, Danish, and Icelandic. It can be use ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regeneration Therapy
Regeneration may refer to: Science and technology * Regeneration (biology), the ability to recreate lost or damaged cells, tissues, organs and limbs * Regeneration (ecology), the ability of ecosystems to regenerate biomass, using photosynthesis * Regeneration in humans, the ability of humans to recreate, or induce the regeneration of, lost tissue * Regenerative (design), a process for resilient and sustainable development * Regenerative agriculture, a sub-category of organic agriculture History and politics *Regeneration (Colombia), La Regeneración, a 19th-century period and political movement in Colombia * Regeneration (Portugal), a 19th-century period in the history of Portugal * The ReGeneration, a cultural generation concerned with environmentalism * Viðreisn (Regeneration), a political party in Iceland founded in 2016 Music * ''Regeneration'' (Stanley Cowell album) (1976) * ''Regeneration'' (Roy Orbison album) (1977) * ''Regeneration'' (The Divine Comedy album) (200 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regeneration (biology)
In biology, regeneration is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete where after the necrotic tissue comes fibrosis. At its most elementary level, regeneration is mediated by the molecular processes of gene regulation and involves the cellular processes of cell proliferation, morphogenesis and cell differentiation. Regeneration in biology, however, mainly refers to the morphogenic processes that characterize the phenotypic plasticity of traits allowing multi-cellular organisms to repair and maintain the integrity of their physiological and morphological states. Above the genetic level, regeneration is fundamentally regulated by asexual cellular processes. Regeneration ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrical Field
An electric field (sometimes E-field) is the physical field that surrounds electrically charged particles and exerts force on all other charged particles in the field, either attracting or repelling them. It also refers to the physical field for a system of charged particles. Electric fields originate from electric charges and time-varying electric currents. Electric fields and magnetic fields are both manifestations of the electromagnetic field, one of the four fundamental interactions (also called forces) of nature. Electric fields are important in many areas of physics, and are exploited in electrical technology. In atomic physics and chemistry, for instance, the electric field is the attractive force holding the atomic nucleus and electrons together in atoms. It is also the force responsible for chemical bonding between atoms that result in molecules. The electric field is defined as a vector field that associates to each point in space the electrostatic (Coulomb) force pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osborn Wave
A J wave — also known as Osborn wave, camel-hump sign, late delta wave, hathook junction, hypothermic wave, K wave, H wave or current of injury — is an abnormal electrocardiogram finding. J waves are positive deflections occurring at the junction between the QRS complex and the ST segment, where the S point, also known as the J point, has a myocardial infarction-like elevation. __TOC__ Causes They are usually observed in people suffering from hypothermia with a temperature of less than 32 °C (90 °F), though they may also occur in people with very high blood levels of calcium (hypercalcemia), brain injury, vasospastic angina, acute pericarditis, or ventricular fibrillation and could also be a normal variant. History The prominent J deflection attributed to hypothermia was first reported in 1938 by Tomaszewski. These waves were then definitively described in 1953 by John J. Osborn (1917–2014) and were named in his honor. Over time, the wave has increasingly been ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nerve
A nerve is an enclosed, cable-like bundle of nerve fibers (called axons) in the peripheral nervous system. A nerve transmits electrical impulses. It is the basic unit of the peripheral nervous system. A nerve provides a common pathway for the electrochemical nerve impulses called action potentials that are transmitted along each of the axons to peripheral organs or, in the case of sensory nerves, from the periphery back to the central nervous system. Each axon, within the nerve, is an extension of an individual neuron, along with other supportive cells such as some Schwann cells that coat the axons in myelin. Within a nerve, each axon is surrounded by a layer of connective tissue called the endoneurium. The axons are bundled together into groups called fascicles, and each fascicle is wrapped in a layer of connective tissue called the perineurium. Finally, the entire nerve is wrapped in a layer of connective tissue called the epineurium. Nerve cells (often called neurons) are f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arthur Guyton
Arthur Clifton Guyton (September 8, 1919 – April 3, 2003) was an American physiologist. Guyton is well known for his ''Textbook of Medical Physiology'', which quickly became the standard text on the subject in medical schools. The first edition was published in 1956, the 10th edition in 2000 (the last before Guyton's death), and the 12th edition in 2010. The 14th edition (2020) is the latest version available. It is the world's best-selling medical physiology textbook and has been translated into at least 15 languages. Textbook of medical physiology ''Textbook of Medical Physiology'' is one of the world's best-selling physiology books and has been translated into at least 13 languages (the textbook memoriam states 13, but the online memoriam states at least 15.) From the ninth edition onwards, John E. Hall co-authored the textbook. However, all prior editions were written entirely by Guyton, with the eighth edition published in 1991. Subsequent editions, including the latest, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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