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Continuous Fever
Continuous fever is a type or pattern of fever in which temperature does not touch the baseline and remains above normal throughout the day. The variation between maximum and minimum temperature in 24 hours is less than 1°C (1.5°F). It usually occurs due to some infectious disease. Diagnosis of continuous fever is usually based on the clinical signs and symptoms but some biological tests, chest X-ray and CT scan are also used. Typhoid fever is an example of continuous fever and it shows a characteristic step-ladder pattern, a step-wise increase in temperature with a high plateau. Examples Continuous fever is manifested in following diseases. * Typhoid fever * Fungal diseases. Management Management is usually symptomatic. Antipyretics like ibuprofen and paracetamol are used for lowering body temperature and body aches. Antibiotics are also recommended for treating infectious diseases. Antibiotics used in treatment of infectious diseases include chloramphenicol, cefotaxime ...
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Chloramphenicol
Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. Its use by mouth or by injection is only recommended when safer antibiotics cannot be used. Monitoring both blood levels of the medication and blood cell levels every two days is recommended during treatment. Common side effects include bone marrow suppression, nausea, and diarrhea. The bone marrow suppression may result in death. To reduce the risk of side effects treatment duration should be as short as possible. People with liver or kidney problems may need lower doses. In young children a condition known as gray baby syndrome may occur which results in a swollen stomach and low blood pressure. Its use near the end of pregnancy and during breastfeeding is typically not recommended. Chloramphenicol is a broad-spectrum ...
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Neutropenic Fever
Febrile neutropenia is the development of fever, often with other signs of infection, in a patient with neutropenia, an abnormally low number of neutrophil granulocytes (a type of white blood cell) in the blood. The term neutropenic sepsis is also applied, although it tends to be reserved for patients who are less well. In 50% of cases, an infection is detectable; bacteremia (bacteria in the bloodstream) is present in approximately 20% of all patients with this condition. Signs and symptoms Fever Causes Febrile neutropenia can develop in any form of neutropenia, but is most generally recognized as a complication of chemotherapy when it is myelosuppressive (suppresses the bone marrow from producing blood cells). Diagnosis MASCC and CISNE risk indexes The Multinational Association for Supportive Care in Cancer (MASCC) risk index can be used to identify low-risk patients (score ≥21 points) for serious complications of febrile neutropenia (including death, intensive care unit admis ...
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Remittent Fever
Remittent fever is a type or pattern of fever in which temperature does not touch the baseline and remains above normal throughout the day. Daily variation in temperature is more than 1°C in 24 hours, which is also the main difference as compared to continuous fever. Fever due to most infectious diseases is remittent. Diagnosis is based upon clinical history, blood tests, blood culture and chest X-ray. Examples Examples of remittent fever are as following. * Infective endocarditis * Typhoid * Brucellosis Management Management is carried out using antipyretics for fever and body aches. Antibiotics are used in case of infectious diseases and for infective endocarditis, in addition to antibiotics, cardiac valve prosthesis and mitral valve replacement surgery is used. See also * Continuous fever * Intermittent fever * Relapsing fever * Undulant fever * Neutropenic fever Febrile neutropenia is the development of fever, often with other signs of infection, in a patient with ne ...
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Relapsing Fever
Relapsing fever is a vector-borne disease caused by infection with certain bacteria in the genus ''Borrelia'', which is transmitted through the bites of lice or soft-bodied ticks (genus ''Ornithodoros''). Signs and symptoms Most people who are infected develop sickness between 5 and 15 days after they are bitten. The symptoms may include a sudden fever, chills, headaches, muscle or joint aches, and nausea. A rash may also occur. These symptoms usually continue for 2 to 9 days, then disappear. This cycle may continue for several weeks if the person is not treated. Causes Louse-borne relapsing fever Along with ''Rickettsia prowazekii'' and ''Bartonella quintana'', ''Borrelia recurrentis'' is one of three pathogens of which the body louse (''Pediculus humanus humanus'') is a vector. Louse-borne relapsing fever is more severe than the tick-borne variety. Louse-borne relapsing fever occurs in epidemics amid poor living conditions, famine and war in the developing world. It is c ...
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Intermittent Fever
Intermittent fever is a type or pattern of fever in which there is an interval where temperature is elevated for several hours followed by an interval when temperature drops back to normal. This type of fever usually occurs during the course of an infectious disease. Diagnosis of intermittent fever is frequently based on the clinical history but some biological tests like complete blood count and blood culture are also used. In addition radiological investigations like chest X-ray, abdominal ultrasonography can also be used in establishing diagnosis. Intermittent fever in malaria Malaria is a common cause of intermittent fever and it has following types. Quotidian fever Bouts of fever occurring daily (24-hour periodicity) for a few hours, typical of Plasmodium knowlesi. Tertian fever Fever occurs after an interval of two days (48-hour periodicity), typical of Plasmodium vivax and Plasmodium ovale. Quartan fever Fever occurs after an interval of three days (72-hour periodic ...
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Amikacin
Amikacin is an antibiotic medication used for a number of bacterial infections. This includes joint infections, intra-abdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis. It is used by injection into a vein using an IV or into a muscle. Amikacin, like other aminoglycoside antibiotics, can cause hearing loss, balance problems, and kidney problems. Other side effects include paralysis, resulting in the inability to breathe. If used during pregnancy it may cause permanent deafness in the baby. Amikacin works by blocking the function of the bacteria's 30S ribosomal subunit, making it unable to produce proteins. Amikacin was patented in 1971, and came into commercial use in 1976. It is on the World Health Organization's List of Essential Medicines. It is derived from kanamycin. Medical uses Amikacin is most often used for treating severe infections with multidrug-resistant, ...
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Gentamicin
Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It is not effective for gonorrhea or chlamydia infections. It can be given intravenously, by intramuscular injection, or topically. Topical formulations may be used in burns or for infections of the outside of the eye. It is often only used for two days until bacterial cultures determine what specific antibiotics the infection is sensitive to. The dose required should be monitored by blood testing. Gentamicin can cause inner ear problems and kidney problems. The inner ear problems can include problems with balance and hearing loss. These problems may be permanent. If used during pregnancy, it can cause harm to the developing baby. However, it appears to be safe for use during breastfeeding. Gentamicin is a type of aminoglycoside. It works by disru ...
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Ciprofloxacin
Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. This includes bone and joint infections, intra abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. For some infections it is used in addition to other antibiotics. It can be taken by mouth, as eye drops, as ear drops, or intravenously. Common side effects include nausea, vomiting, and diarrhea. Severe side effects include an increased risk of tendon rupture, hallucinations, and nerve damage. In people with myasthenia gravis, there is worsening muscle weakness. Rates of side effects appear to be higher than some groups of antibiotics such as cephalosporins but lower than others such as clindamycin. Studies in other animals raise concerns regarding use in pregnancy. No problems were identified, however, in the children of a small number of women who took the medication. It ...
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Cefotaxime
Cefotaxime is an antibiotic used to treat a number of bacterial infections in human, other animals and plant tissue culture. Specifically in humans it is used to treat joint infections, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, sepsis, gonorrhea, and cellulitis. It is given either by injection into a vein or muscle. Common side effects include nausea, allergic reactions, and inflammation at the site of injection. Another side effect may include ''Clostridium difficile'' diarrhea. It is not recommended in people who have had previous anaphylaxis to a penicillin. It is relatively safe for use during pregnancy and breastfeeding. It is in the third-generation cephalosporin family of medications and works by interfering with the bacteria's cell wall. Cefotaxime was discovered in 1976, and came into commercial use in 1980. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. Medica ...
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Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antisep ...
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