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Clinical Pharmaceutical Scientist
A clinical pharmaceutical scientist (or pharmacist-scientist) is a licensed, practicing pharmacist who also functions as an independent researcher in the pharmaceutical sciences. Clinical pharmaceutical scientists are a type of clinician scientist, analogous to physician-scientists. Terminology The term clinical pharmaceutical scientist is distinct from the term pharmaceutical scientist, in that a clinical pharmaceutical scientist is a practicing clinical pharmacist involved in science relating to the discovery and/or development of pharmaceuticals, the development of new knowledge improving the use of pharmaceuticals in clinical practice, or any other subfield of pharmaceutical science (e.g. pharmacoeconomics, pharmacokinetics, outcomes research), while a pharmaceutical scientist need not also be a clinician (pharmacist). Thus, all clinical pharmaceutical scientists are pharmaceutical scientists, but not all pharmaceutical scientists are clinical pharmaceutical scientists. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process – from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials – to approved vaccine or drug typically takes more than a decade. New chemical entity development Broadly, the process of drug development can be divided into preclinical and clinical work. Pre-clinical New chemical entities (NCEs, also known as new molecular entities or NMEs) are compounds that emerge from the process of drug discovery. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Sertürner
Friedrich Wilhelm Adam Sertürner (19 June 1783 – 20 February 1841) was a German pharmacist and a pioneer of alkaloid chemistry. He is best known for his discovery of morphine in 1804. Biography Friedrich Wilhelm Adam Sertürner was born to Joseph Simon Serdinner and Marie Therese Brockmann on 19 June 1783, in Neuhaus, North Rhine-Westphalia (now part of Paderborn). After his parents died, he became a pharmacist's apprentice in Paderborn. Sertürner was the first to isolate morphine from opium. He called the isolated alkaloid "morphium" after the Greek god of dreams, Morpheus. He published a comprehensive paper on its isolation, crystallization, crystal structure, and pharmacological properties, which he studied first in stray dogs and then in self-experiments. Morphine was not only the first alkaloid to be extracted from opium, but the first ever alkaloid to be isolated from any plant. Thus Sertürner became the first person to isolate the active ingredient associated with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
History Of Pharmacy
The history of pharmacy as an independent science dates back to the first third of the 19th century. Before then, pharmacy evolved from antiquity as part of medicine. The history of pharmacy coincides well with the history of medicine, but it's important that there is a distinction between the two topics. Pharmaceuticals is one of the most-researched fields in the academic industry, but the history surrounding that particular topic is sparse compared to the impact its made world-wide. Before the advent of pharmacists, there existed apothecaries that worked alongside priests and physicians in regard to patient care. Prehistoric Pharmacy Paleopharmacological studies attest to the use of medicinal plants in pre-history. For example, herbs were discovered in the Shanidar Cave, and remains of the areca nut (''Areca catechu)'' in the Spirit Cave. Prehistoric man learned pharmaceutical techniques through instinct, by watching birds and beasts, and using cool water, leaves, dirt, or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Misuse
Substance abuse, also known as drug abuse, is the use of a drug in amounts or by methods which are harmful to the individual or others. It is a form of substance-related disorder. Differing definitions of drug abuse are used in public health, medical and criminal justice contexts. In some cases, criminal or anti-social behaviour occurs when the person is under the influence of a drug, and long-term personality changes in individuals may also occur. In addition to possible physical, social, and psychological harm, the use of some drugs may also lead to criminal penalties, although these vary widely depending on the local jurisdiction.. Drugs most often associated with this term include: alcohol, amphetamines, barbiturates, benzodiazepines, cannabis, cocaine, hallucinogens (although there is no known ''psychedelic'', one of the three categories of hallucinogens, that has been found to have any addictive potential), methaqualone, and opioids. The exact cause of substance abuse i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prescription Drug
A prescription drug (also prescription medication or prescription medicine) is a pharmaceutical drug that legally requires a medical prescription to be dispensed. In contrast, over-the-counter drugs can be obtained without a prescription. The reason for this difference in substance control is the potential scope of misuse, from drug abuse to practicing medicine without a license and without sufficient education. Different jurisdictions have different definitions of what constitutes a prescription drug. In North America, ℞, usually printed as "Rx", is used as an abbreviation of the word "prescription". It is a contraction of the Latin word "''recipe''" (an imperative form of "recipere") meaning "take". Prescription drugs are often dispensed together with a monograph (in Europe, a Patient Information Leaflet or PIL) that gives detailed information about the drug. The use of prescription drugs has been increasing since the 1960s. Regulation Australia In Australia, the Standar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacy School
The basic requirement for pharmacists to be considered for registration is often an undergraduate or postgraduate pharmacy degree from a recognized university. In many countries, this involves a four- or five-year course to attain a bachelor of pharmacy or Master of Pharmacy, master of pharmacy degree. In the United States since 2003, students must complete a doctor of pharmacy degree to become a licensed pharmacist, with a similar requirement being introduced in some other countries such as Canada and France. The doctor of pharmacy degree usually requires completion of four years at an accredited college of pharmacy after an undergraduate degree or other approved courses. To practice as a pharmacist, registration with the country, state, or province's regulatory agency is required. There is often a requirement for the pharmacy graduate to have completed a certain number of hours of experience in a pharmacy under the supervision of a registered pharmacist. If the regulator ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health Care In The United States
The United States far outspends any other nation on health care, measured both in ''per capita'' spending and as a percentage of GDP. Despite this, the country has significantly worse healthcare outcomes when compared to peer nations. The United States is the only developed nation without a system of universal health care, with a large proportion of its population not carrying health insurance, a substantial factor in the country's excess mortality. Healthcare is provided by many distinct organizations, made up of insurance companies, healthcare providers, hospital systems, and independent providers. Health care facilities are largely owned and operated by private sector businesses. 58% of community hospitals in the United States are non-profit, 21% are government-owned, and 21% are for-profit. According to the World Health Organization (WHO), the United States spent $9,403 on health care per capita, and 17.9% on health care as percentage of its GDP in 2014. Healthcare cove ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Pharmacology
Clinical pharmacology has been defined as "that discipline that teaches, does research, frames policy, gives information and advice about the actions and proper uses of medicines in humans and implements that knowledge in clinical practice". Clinical Pharmacology is inherently a translational discipline underpinned by the basic science of pharmacology, engaged in the experimental and observational study of the disposition and effects of drugs in humans, and committed to the translation of science into evidence-based therapeutics. It has a broad scope, from the discovery of new target molecules to the effects of drug usage in whole populations. The main aim of clinical pharmacology is to generate data for optimum use of drugs and the practice of 'evidence based medicine'. Clinical pharmacologists have medical and scientific training that enables them to evaluate evidence and produce new data through well-designed studies. Clinical pharmacologists must have access to enough patie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinician
A clinician is a health care professional typically employed at a skilled nursing facility or clinic. Clinicians work directly with patients rather than in a laboratory or as a researcher. A clinician may diagnose, treat, and otherwise care for patients. For example, psychologists, clinical pharmacists, clinical scientists, nurses, physiotherapists, dentists, optometrists, physician assistants and physicians can be considered clinicians. Many clinicians take comprehensive exams to be licensed and some complete graduate degrees (master's or doctorates) in their field of expertise. A main function of a clinician is to manage a sick person in order to cure the effects of their illness. The clinician can also consider the impact of illness upon the patient and his or her family, as well as other social factors. See also * List of healthcare occupations A listing of health care professions by medical discipline. Anesthesiology * Anesthesiologist * Anesthesiology Fellow * Certifi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Outcomes Research
Outcomes research is a branch of public health research which studies the end results ( outcomes) of the structure and processes of the health care system on the health and well-being of patients and populations. According to one medical outcomes and guidelines source book - 1996, ''Outcomes research'' includes health services research that focuses on identifying variations in medical procedures and associated health outcomes. Though listed as a synonym for the National Library of Medicine MeSH term "Outcome Assessment (Health Care)", outcomes research may refer to both health services research and healthcare outcomes assessment, which aims at Health technology assessment, decision making, and policy analysis through systematic evaluation of quality of care, access, and effectiveness. Description Outcomes research is applied to clinical and population based research that seeks to study and optimize the end results of healthcare in terms of benefits to the patient and society. The i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacokinetics
Pharmacokinetics (from Ancient Greek ''pharmakon'' "drug" and ''kinetikos'' "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models. Overview Pharmacokinetics describes how the body affects a specific xenobiotic/chemical after administration through the mechanisms of absorption and distribution, as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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