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Cincinnati Water Maze
The Cincinnati Water Maze (CWM) is a type of water maze. Water mazes are experimental equipment used in laboratories; they are mazes that are partially filled with water, and rodents are put in them to be observed and timed as they make their way through the maze. Generally two sets of rodents are put through the maze, one that has been treated, and another that has not, and the results are compared. The experimenter uses this type of maze to learn about the subject's cognitive or emotional processes. Overview The Cincinnati Water Maze is a water maze that has nine interconnected T-intersections. The rats are forced to find their way from one end of the maze to the other by navigating through openings in the side of the walls rather than at the end of each passage. The walls are wide enough so that the rat cannot prop itself up on the wall, and the walls are made out of Plexiglas, to prevent the subjects from carrying out any unwanted behavior such as climbing over the wall, or ...
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Cincinnati Water Maze
The Cincinnati Water Maze (CWM) is a type of water maze. Water mazes are experimental equipment used in laboratories; they are mazes that are partially filled with water, and rodents are put in them to be observed and timed as they make their way through the maze. Generally two sets of rodents are put through the maze, one that has been treated, and another that has not, and the results are compared. The experimenter uses this type of maze to learn about the subject's cognitive or emotional processes. Overview The Cincinnati Water Maze is a water maze that has nine interconnected T-intersections. The rats are forced to find their way from one end of the maze to the other by navigating through openings in the side of the walls rather than at the end of each passage. The walls are wide enough so that the rat cannot prop itself up on the wall, and the walls are made out of Plexiglas, to prevent the subjects from carrying out any unwanted behavior such as climbing over the wall, or ...
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Animal Testing Mazes
Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia. With few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of cells, the blastula, during embryonic development. Over 1.5 million living animal species have been described—of which around 1 million are insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a bilaterally symmetric body plan. The Bilateria include the protostomes, containing animals such as nematodes, arthropods, flatworms, annelids and molluscs, and the deuterostomes, containing the echinoderms and ...
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Radial Arm Maze
The radial arm maze was designed by Olton and Samuelson in 1976 to measure spatial learning and memory in rats. The original apparatus consists of eight equidistantly spaced arms, each about 4 feet long, and all radiating from a small circular central platform (later versions have used as few as three and as many as 48 arms). At the end of each arm there is a food site, the contents of which are not visible from the central platform. Two types of memory that are assessed during the performance in this task are reference memory and working memory. Reference memory is assessed when the rats only visit the arms of the maze which contains the reward. The failure to do so will result in reference memory error. Working memory is assessed when the rats enter each arm a single time. Re-entry into the arms would result in a working memory error. The design ensures that, after checking for food at the end of each arm, the rat is always forced to return to the central platform before making ...
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Morris Water Navigation Task
The Morris water navigation task, also known as the Morris water maze (not to be confused with '' water maze''), is a behavioral procedure mostly used with rodents. It is widely used in behavioral neuroscience to study spatial learning and memory. It enables learning, memory, and spatial working to be studied with great accuracy, and can also be used to assess damage to particular cortical regions of the brain. It is used by neuroscientists to measure the effect of neurocognitive disorders on spatial learning and possible neural treatments, to test the effect of lesions to the brain in areas concerned with memory, and to study how age influences cognitive function and spatial learning. The task is also used as a tool to study drug-abuse, neural systems, neurotransmitters, and brain development. Overview The basic procedure for the Morris water navigation task is that the rat is placed in a large circular pool and is required to find an invisible or visible platform that all ...
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Spatial Memory
In cognitive psychology and neuroscience, spatial memory is a form of memory responsible for the recording and recovery of information needed to plan a course to a location and to recall the location of an object or the occurrence of an event. Spatial memory is necessary for orientation in space. Spatial memory can also be divided into egocentric and allocentric spatial memory. A person's spatial memory is required to navigate around a familiar city. A rat's spatial memory is needed to learn the location of food at the end of a maze. In both humans and animals, spatial memories are summarized as a cognitive map. Spatial memory has representations within working, short-term memory and long-term memory. Research indicates that there are specific areas of the brain associated with spatial memory. Many methods are used for measuring spatial memory in children, adults, and animals. Short-term spatial memory Short-term memory (STM) can be described as a system allowing one to tempora ...
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Short-term Memory
Short-term memory (or "primary" or "active memory") is the capacity for holding a small amount of information in an active, readily available state for a short interval. For example, short-term memory holds a phone number that has just been recited. The duration of short-term memory (absent rehearsal or active maintenance) is estimated to be on the order of seconds. The commonly cited capacity of 7 items, found in Miller's Law, has been superseded by 4±1 items. In contrast, long-term memory holds information indefinitely. Short-term memory is not the same as working memory, which refers to structures and processes used for temporarily storing and manipulating information. Stores The idea of separate memories for short-term and long-term storage originated in the 19th century. A model of memory developed in the 1960s assumed that all memories are formed in one store and transfer to others store after a small period of time. This model is referred to as the "modal model", most ...
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Procedural Memory
Procedural memory is a type of implicit memory (unconscious, long-term memory) which aids the performance of particular types of tasks without conscious awareness of these previous experiences. Procedural memory guides the processes we perform, and most frequently resides below the level of conscious awareness. When needed, procedural memories are automatically retrieved and utilized for execution of the integrated procedures involved in both cognitive and motor skills, from tying shoes, to reading, to flying an airplane. Procedural memories are accessed and used without the need for conscious control or attention. Procedural memory is created through ''procedural learning'', or repeating a complex activity over and over again until all of the relevant neural systems work together to automatically produce the activity. Implicit procedural learning is essential for the development of any motor skill or cognitive activity. History The difference between procedural and declarativ ...
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Biel Water Maze
, french: Biennois(e) , neighboring_municipalities= Brügg, Ipsach, Leubringen/Magglingen (''Evilard/Macolin''), Nidau, Orpund, Orvin, Pieterlen, Port, Safnern, Tüscherz-Alfermée, Vauffelin , twintowns = Iserlohn (Germany) Biel/Bienne (official bilingual wording; , ) is a town and a municipality in the Biel/Bienne administrative district in the canton of Bern in Switzerland. Biel/Bienne lies on the language boundary between the French-speaking and German-speaking parts of Switzerland, and is bilingual throughout. ''Biel'' is the German name for the town; ''Bienne'' its French counterpart. The town is often referred to in both languages simultaneously. Since 1 January 2005, the official name has been "Biel/Bienne". Until then, the town was officially named Biel. The town lies at the foot of the first mountain range of the Jura Mountains area, guarding the only practical connection to Jura, on the northeastern shores of Lake Biel (, ), sharing the ...
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Water Maze (neuroscience)
A water maze is a device used to test an animal's memory in which the alleys are filled with water, providing a motivation to escape. Many different mazes exist, such as T- and Y-mazes, Cincinnati water mazes, and radial arm mazes. Water mazes have been used to test discrimination learning and spatial learning abilities. The Morris water navigation task is often called a "water maze task", but this is erroneous as it is not, properly speaking, a maze. The development of these mazes has aided research into, for example, hippocampal synaptic plasticity, NMDA receptor function, and looking into neurodegenerative diseases, such as Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me .... References Behavioral neuroscience {{Neuroscience-stub ...
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Allothetic
Allothetic means being centred in people or places other than oneself. It has been defined as a process of "determining and maintaining a course or trajectory from one place to another. It can be used as a navigational strategy among animals to aid in their survival. It can also be a source of information for machines, particularly those biologically-inspired models and is provided by a set of laser rangefinders, sonars, or vision. Allothetic is used in navigation models (e.g., of a rat in a maze) as in the phrase "allothetic map" to indicate that a global map, not orientated or centred on the subject was used, rather than idiothetic, which means a navigation system centred on the subject. Directional information may be sourced from familiar reference points such as the sun, stars, or the Earth's magnetic field. Allothetic cues are often employed with idiothetic information to achieve spatial behavior. Their characteristics are complementary such as the way the latter can help ad ...
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Idiothetic
Idiothetic literally means "self-proposition" (Greek derivation), and is used in navigation models (e.g., of a rat in a maze) to describe the use of self-motion cues, rather than allothetic, or external, cues such as landmarks, to determine position and movement. The word is sometimes also spelled "ideothetic" (e.g., Chen et al, 1994 ). Idiothetic cues include vestibular, optic flow and proprioception. Idiothetic cues are important for the type of navigation known as path integrationMittelstaedt, H. and Mittelstaedt, M.-L. (1973). "Mechanismen der orientierung ohne richtende aussenreize." Fortschr. Zool. 21:46–58. in which subjects navigate purely using such self-motion cues. This is achieved by an animal through the signals generated by angular and linear accelerations in the course of its exploration. These information generate and update a vector towards the starting point and an accurate path for return. The term ''idiothetic'' is also used in robotics and in personality p ...
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