Centre For Genomic Regulation
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Centre For Genomic Regulation
The Centre for Genomic Regulation (CRG, ''Centre de Regulació Genòmica'' in Catalan) is a biomedical and genomics research centre based on Barcelona. Most of its facilities and laboratories are located in the Barcelona Biomedical Research Park, in front of Somorrostro beach. Since July 2015 CNAG (the National Centre for Genomic Analysis), located in the Parc Científic de Barcelona (close to Camp Nou), became an outstation of CRG. CRG is member of EU-LIFE, an alliance of leading life sciences research centres in Europe. Research programs Bioinformatics and Genomics There are several lines of research within Bioinformatics and Genomics. Gene Prediction and Modeling of Splicing is related to the research on Regulation of Alternative Splicing, Regulation of Protein Synthesis within the Gene Regulation program, and Genes and Diseases program. Another research line involves identification and characterization of genomic regions associated with gene regulation. This is connect ...
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Barcelona
Barcelona ( , , ) is a city on the coast of northeastern Spain. It is the capital and largest city of the autonomous community of Catalonia, as well as the second most populous municipality of Spain. With a population of 1.6 million within city limits,Barcelona: Población por municipios y sexo
– Instituto Nacional de Estadística. (National Statistics Institute)
its urban area extends to numerous neighbouring municipalities within the and is home to around 4.8 million people, making it the
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Spain
, image_flag = Bandera de España.svg , image_coat = Escudo de España (mazonado).svg , national_motto = ''Plus ultra'' (Latin)(English: "Further Beyond") , national_anthem = (English: "Royal March") , image_map = , map_caption = , image_map2 = , capital = Madrid , coordinates = , largest_city = Madrid , languages_type = Official language , languages = Spanish language, Spanish , ethnic_groups = , ethnic_groups_year = , ethnic_groups_ref = , religion = , religion_ref = , religion_year = 2020 , demonym = , government_type = Unitary state, Unitary Parliamentary system, parliamentary constitutional monarchy , leader_title1 = Monarchy of Spain, Monarch , leader_name1 = Felipe VI , leader_title2 = Prime Minister of Spain ...
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Catalan Language
Catalan (; autonym: , ), known in the Valencian Community and Carche as ''Valencian'' (autonym: ), is a Western Romance language. It is the official language of Andorra, and an official language of three autonomous communities in eastern Spain: Catalonia, the Valencian Community, and the Balearic Islands. It also has semi-official status in the Italian comune of Alghero. It is also spoken in the Pyrénées-Orientales department of France and in two further areas in eastern Spain: the eastern strip of Aragon and the Carche area in the Region of Murcia. The Catalan-speaking territories are often called the or "Catalan Countries". The language evolved from Vulgar Latin in the Middle Ages around the eastern Pyrenees. Nineteenth-century Spain saw a Catalan literary revival, culminating in the early 1900s. Etymology and pronunciation The word ''Catalan'' is derived from the territorial name of Catalonia, itself of disputed etymology. The main theory suggests that (Latin ...
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Medical Research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine. Both clinical and preclinical research phases exist in the pharmaceutical industry's drug development pipelines, where the clinical phase is denoted by the term ''clinical trial''. However, only part of the clinical or preclinical research is oriented towards a specific pharmaceutical purpose. The need for fundamental and mechanism-based understanding, diagnostics, medical devices, and non-pharmaceutical therapies means that pharmaceutical research i ...
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ...
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Barcelona Biomedical Research Park
The Barcelona Biomedical Research Park ("PRBB") is an agglomeration of six public research centres and is located alongside the Hospital del Mar de Barcelona. The PRBB is the product of an initiative launched by the Government of Catalonia, the City Council of Barcelona and the Pompeu Fabra University (UPF), which aims to promote research and collaboration between closely related fields. Each centre works independently in its own field and a management group, the PRBB Consortium, is responsible for managing the building and facilities, in addition to coordinating joint scientific research activities among the various centres. About 1,400 people are employed in the PRBB, making it one of the largest biomedical research clusters in the south of Europe. The centre was opened in May 2006. The PRBB building was designed by the architects Manuel Brullet i Tenas and Albert de Pineda i Àlvarez. Overview PRBB comprises the following six research centres: * Hospital del Mar Medical ...
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Somorrostro
Somorrostro Beach is one of the beaches in Barcelona, Catalonia, Spain. It is located between Hospital del Mar and Marina Street, in the far east area of the Barceloneta neighborhood, in the Ciutat Vella district. It is long and wide. The Somorrostro name was forgotten and the beach became one of the most popular in the city. It was not until 2010, Somorrostro beach got its original name back. History During the 19th century and part of the 20th century, the beach, and much of the neighboring beach areas was occupied by a shanty town, inhabited by 15,000 people living in 2,000 slums. Known during this time as a Romani community. It was not until the 1966 visit of Spanish caudillo Francisco Franco that the slum removal began. Most of these slums were pulled down between the 1960s and 1980s. Famous gypsy flamenco dancers Carmen Amaya and Antoñita Singla were born in that neighborhood. ''Los Tarantos'', an academy award The Academy Awards, better known as the Oscars, ar ...
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Centro Nacional De Análisis Genómico
The National Center for Genomic Analysis (CNAG, ''Centre Nacional d'Anàlisi Genòmica'' in Catalan, ''Centro Nacional de Análisis Genómico'' in Spanish) is a genome analysis center in Barcelona that carries out large-scale projects in collaboration with researchers from Catalonia, Spain and the International research community. It has a park of last-generation sequencing systems supported by an outstanding computing infrastructure of 14 petabytes of data storage and over 10.000 cores of computing, which has enabled the center to build a sequencing capacity of over 10.000 Gbases/day, the equivalent of completely sequencing 100 human genomes every 24 hours. This capacity positions the CNAG as one of the top European centers in terms of sequencing capacity. It is a non-profit organization founded in 2009 by the Spanish Ministry of Science and Innovation and the Catalan Government through the Economy and Knowledge Department and the Health Department. It is located in the Barcelon ...
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Camp Nou
Camp Nou (, meaning ''new field'', often referred to in English as the Nou Camp), officially branded as Spotify Camp Nou for sponsorship and financial reasons, is a football stadium in Barcelona, Spain. It has been the home stadium of FC Barcelona since its completion in 1957. With a current seating capacity of 99,354, it is the largest stadium in Spain and Europe, and the fourth largest association football stadium in the world. It has hosted two European Cup/Champions League finals in 1989 and 1999, two European Cup Winners' Cup finals, four Inter-Cities Fairs Cup final games, five UEFA Super Cup games, four Copa del Rey finals, two Copa de la Liga finals, and twenty-one Supercopa de España finals. It also hosted five matches in the 1982 FIFA World Cup (including the opening game), two out of four matches at the 1964 European Nations' Cup, and the football tournament's final at the 1992 Summer Olympics. On 15 March 2022, it was announced that music streaming service ...
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Organoid
An organoid is a miniaturized and simplified version of an Organ (anatomy), organ produced in vitro in three dimensions that shows realistic micro-anatomy. They are derived from one or a few Cell (biology), cells from a Tissue (biology), tissue, embryonic stem cells or induced pluripotent stem cells, which can Self-organization, self-organize in three-dimensional culture owing to their Stem cell, self-renewal and Cellular differentiation, differentiation capacities. The technique for growing organoids has rapidly improved since the early 2010s, and it was named by ''The Scientist (magazine), The Scientist'' as one of the biggest scientific advancements of 2013. Organoids are used by scientists to study disease and treatments in a laboratory. History Attempts to create organ (biology), organs ''in vitro'' started with one of the first dissociation-reaggregation experiments where Henry Van Peters Wilson demonstrated that mechanically dissociated sponge cells can reaggregate and se ...
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Genetics Or Genomics Research Institutions
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Phenotypic trait, Trait inheritance and Molecular genetics, molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the Cell (biolo ...
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