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Center For The Study Of Human Polymorphisms
The Fondation Jean Dausset-CEPH or CEPH, formerly the Centre d'Etude du Polymorphisme Humain (the ''Center for the Study of Human Polymorphisms''), is an international genetic research center located in Paris, France. It produced a map that includes genetic markers of human chromosomes using a resource of immortalised cell cultures. Background In his 2005 addendum to his biography for the 1980 Nobel Prize, Jean Dausset noted that, thanks to his Nobel Prize and a grant from the French Téléthon, he had been able in 1984 to create the Human Polymorphism Study Centre (CEPH), which soon after became Foundation Jean Dausset-CEPH. Dausset founded CEPH with the collaboration of Professors Howard Cann and Daniel Cohen. The scientific director of CEPH is currently Jean-François Deleuze and its president is François d'Aubert, a French politician, an auditor at the Cour des Comptes and a former minister delegate to research. Human genome Numerous collaborators working on the same lar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centre Etude Polymorphisme Humain Institut Genetique Moleculaire Paris France
Center or centre may refer to: Mathematics *Center (geometry), the middle of an object * Center (algebra), used in various contexts ** Center (group theory) ** Center (ring theory) * Graph center, the set of all vertices of minimum eccentricity Places United States * Centre, Alabama * Center, Colorado * Center, Georgia * Center, Indiana * Center, Jay County, Indiana * Center, Warrick County, Indiana * Center, Kentucky * Center, Missouri * Center, Nebraska * Center, North Dakota * Centre County, Pennsylvania * Center, Portland, Oregon * Center, Texas * Center, Washington * Center, Outagamie County, Wisconsin * Center, Rock County, Wisconsin **Center (community), Wisconsin *Center Township (other) *Centre Township (other) *Centre Avenue (other) *Center Hill (other) Other countries * Centre region, Hainaut, Belgium * Centre Region, Burkina Faso * Centre Region (Cameroon) * Centre-Val de Loire, formerly Centre, France * Centre (department), Ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
François D'Aubert
François d'Aubert (born 31 October 1943, in Boulogne-Billancourt) is a French politician. He is an auditor at the Court of Audit. From 2002, he was minister delegate to research in Jean-Pierre Raffarin's government. From 26 July 2007 to 16 April 2009, he was president of the Cité des Sciences et de l'Industrie The Cité des Sciences et de l'Industrie ("City of Science and Industry", abbreviated la CSI) or simply CSI is the biggest science museum in Europe. Located in the Parc de la Villette in Paris, France, it is one of the three dozen French Cultur .... External links *Official page 1943 births Living people Politicians of the French Fifth Republic Lycée Louis-le-Grand alumni HEC Paris alumni Sciences Po alumni École nationale d'administration alumni French Ministers of Budget Officers of the Ordre national du Mérite The Republicans (France) politicians Deputies of the 12th National Assembly of the French Fifth Republic {{France-politician-UMP- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centenarian
A centenarian is a person who has reached the age of 100 years. Because life expectancies worldwide are below 100 years, the term is invariably associated with longevity. In 2012, the United Nations estimated that there were 316,600 living centenarians worldwide. As world population and life expectancy continue to increase, the number of centenarians is expected to increase substantially in the 21st century. According to the UK ONS, one-third of babies born in 2013 in the UK are expected to live to 100. The United Nations predicts that there are 573,000 centenarians currently, almost quadruple the 151,000 suggested in the year 2000. According to a 1998 United Nations demographic survey, Japan is expected to have 272,000 centenarians by 2050; other sources suggest that the number could be closer to 1 million. The incidence of centenarians in Japan was one per 3,522 people in 2008. In Japan, the number of centenarians is highly skewed towards females. Japan in fiscal year 2016 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of regulatory RNAs. It also includes promoters and their associated gene-regulatory elements, DNA playing structural and replicatory roles, such as scaffolding regions, telomeres, centromeres, and origins of replication, plus large numbers of transposable elements, inserted viral DNA, non-functional pseudogenes and simple, highly-repetitive sequences. Introns make up a large percentage of non-coding DNA. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physical Map
A map is a symbolic depiction emphasizing relationships between elements of some space, such as objects, regions, or themes. Many maps are static, fixed to paper or some other durable medium, while others are dynamic or interactive. Although most commonly used to depict geography, maps may represent any space, real or fictional, without regard to context or scale, such as in brain mapping, DNA mapping, or computer network topology mapping. The space being mapped may be two dimensional, such as the surface of the earth, three dimensional, such as the interior of the earth, or even more abstract spaces of any dimension, such as arise in modeling phenomena having many independent variables. Although the earliest maps known are of the heavens, geographic maps of territory have a very long tradition and exist from ancient times. The word "map" comes from the , wherein ''mappa'' meant 'napkin' or 'cloth' and ''mundi'' 'the world'. Thus, "map" became a shortened term referring to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Map
Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more ''linked'' than markers that are far apart. In other words, the nearer two genes are on a chromosome, the lower the chance of recombination between them, and the more likely they are to be inherited together. Markers on different chromosomes are perfectly ''unlinked'', although the penetrance of potentially deleterious alleles may be influenced by the presence of other alleles, and these other alleles may be located on other chromosomes than that on which a particular potentially deleterious allele is located. Genetic linkage is the most prominent exception to Gregor Mendel's Law of Independent Assortment. The first experiment to demonstrate lin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Leukocyte Antigen
The human leukocyte antigen (HLA) system or complex is a complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for the regulation of the immune system. The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. Mutations in HLA genes may be linked to autoimmune disease such as type I diabetes, and celiac disease. The HLA gene complex resides on a 3 Mbp stretch within chromosome 6, p-arm at 21.3. HLA genes are highly polymorphic, which means that they have many different alleles, allowing them to fine-tune the adaptive immune system. The proteins encoded by certain genes are also known as ''antigens'', as a result of their historic discovery as factors in organ transplants. HLAs corresponding to MHC class I ( A, B, and C), all of which are the HLA Class1 group, present peptides from inside the cell. For example, if the cell is infected by a virus, the HLA system brings fragme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jean-François Deleuze
Jean-François is a French given name. Notable people bearing the given name include: * Jean-François Carenco (born 1952), French politician * Jean-François Champollion (1790–1832), French Egyptologist * Jean-François Clervoy (born 1958), French engineer and astronaut * Jean-François Corminboeuf (born 1953), Swiss sport sailor * Jean-François Dagenais (born 1975), Canadian music producer * Jean-François David (born 1982), Canadian ice hockey player * Jean-François Gariépy (born 1984), Canadian alt-right political commentator and former neuroscientist * Jean-François Garreaud (1946–2020), French actor * Jean-François de La Harpe (1739–1803), French critic * Jean-François Lyotard (1924-1998), French philosopher * Jean-François Marceau (born 1976), Canadian judoka * Jean-François Marmontel Jean-François Marmontel (11 July 1723 – 31 December 1799) was a French historian, writer and a member of the Encyclopédistes movement. Biography He was born of poor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polymorphism (biology)
In biology, polymorphism is the occurrence of two or more clearly different morphs or forms, also referred to as alternative ''phenotypes'', in the population of a species. To be classified as such, morphs must occupy the same habitat at the same time and belong to a panmictic population (one with random mating). Ford E.B. 1965. ''Genetic polymorphism''. Faber & Faber, London. Put simply, polymorphism is when there are two or more possibilities of a trait on a gene. For example, there is more than one possible trait in terms of a jaguar's skin colouring; they can be light morph or dark morph. Due to having more than one possible variation for this gene, it is termed 'polymorphism'. However, if the jaguar has only one possible trait for that gene, it would be termed "monomorphic". For example, if there was only one possible skin colour that a jaguar could have, it would be termed monomorphic. The term polyphenism can be used to clarify that the different forms arise from the s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jean Dausset
Jean-Baptiste-Gabriel-Joachim Dausset (19 October 1916 – 6 June 2009) was a French immunologist born in Toulouse, France. Dausset received the Nobel Prize in Physiology or Medicine in 1980 along with Baruj Benacerraf and George Davis Snell for their discovery and characterisation of the genes making the major histocompatibility complex. Using the money from his Nobel Prize and a grant from the French Television, Dausset founded the Human Polymorphism Study Center ( CEPH) in 1984, which was later renamed the Foundation Jean Dausset-CEPH in his honour. He married Rose Mayoral in 1963, with whom he had two children, Henri and Irène. Jean Dausset died on June 6, 2009 in Majorca, Spain, at the age of 92. Early life Jean-Baptiste-Gabriel-Joachim Dausset was born on 19 October 1916, in Toulouse, France. He was the youngest of four children of Henri Dausset and Elisabeth Dausset (born Renard). His father was from the Pyrénées, and was a doctor by profession, and his mother was a h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfred Nobel was a Swedish chemist, engineer, and industrialist most famously known for the invention of dynamite. He died in 1896. In his will, he bequeathed all of his "remaining realisable assets" to be used to establish five prizes which became known as "Nobel Prizes." Nobel Prizes were first awarded in 1901. Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace (Nobel characterized the Peace Prize as "to the person who has done the most or best to advance fellowship among nations, the abolition or reduction of standing armies, and the establishment and promotion of peace congresses"). In 1968, Sveriges Riksbank (Sweden's central bank) funded the establishment of the Prize in Economi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
