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Carl Faingold
Carl L. Faingold is an American neuroscientist who is a Distinguished Professor in the Department of Pharmacology of Southern Illinois University School of Medicine in Springfield, Illinois; he is a founding faculty member of both the department and the School of Medicine. He has had an extensive career as a medical and graduate student educator as well as a researcher into brain mechanisms. He is a specialist in the actions of drugs on brain activity at the level of the single neuron as it relates to networks of neurons in awake behaving animals. Education Faingold received his B.S. in Pharmacy from the University of Illinois at Chicago in 1965, and a Ph.D. in pharmacology from Northwestern University in 1970. This was followed by a post-doctoral fellowship at the University of Missouri Institute of Psychiatry. He is a long-time member of the American Society for Pharmacology and Experimental Therapeutics ASPET, the Research Society on Alcoholism RSA, the American Epil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Southern Illinois University School Of Medicine
Southern Illinois University School of Medicine is a medical school located in Springfield, the capital of the U.S. state of Illinois. It is part of the Southern Illinois University system, which includes a campus in Edwardsville as well as the flagship in Carbondale. The medical school was founded in 1970 and achieved full accreditation in 1972. It was founded to relieve a chronic shortage of physicians in downstate Illinois. Notability SIU was once the only medical school in Illinois with its main campus outside of Chicago or its suburbs until the Carle Illinois College of Medicine was formed in 2018 (although the University of Illinois at Chicago does maintain satellites in Peoria and Rockford). SIU was early to incorporate problem-based learning (PBL) into their curricula (see below) and "standardized patients" for medical student testing purposes. Being able to interact with standardized patients now comprises the majority of one of the four major exams that all US ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Illinois At Chicago
The University of Illinois Chicago (UIC) is a Public university, public research university in Chicago, Illinois. Its campus is in the Near West Side, Chicago, Near West Side community area, adjacent to the Chicago Loop. The second campus established under the University of Illinois system, UIC is also the largest university in the Chicago metropolitan area, having more than 33,000 students enrolled in 16 colleges. It is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity." The roots of UIC can be traced to the establishment of the Chicago College of Pharmacy in 1859, which was joined in the 1800s by additional medical related schools. It began an undergraduate program toward the end of World War II, and developed its West side campus in the 1960s. In 1982, it consolidated the University of Illinois at Chicago Circle and the University of Illinois at the Medical Center into the present universi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Northwestern University
Northwestern University is a private research university in Evanston, Illinois. Founded in 1851, Northwestern is the oldest chartered university in Illinois and is ranked among the most prestigious academic institutions in the world. Chartered by the Illinois General Assembly in 1851, Northwestern was established to serve the former Northwest Territory. The university was initially affiliated with the Methodist Episcopal Church but later became non-sectarian. By 1900, the university was the third largest university in the United States. In 1896, Northwestern became a founding member of the Big Ten Conference, and joined the Association of American Universities as an early member in 1917. The university is composed of eleven undergraduate, graduate, and professional schools, which include the Kellogg School of Management, the Pritzker School of Law, the Feinberg School of Medicine, the Weinberg College of Arts and Sciences, the Bienen School of Music, the McCormick ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Missouri
The University of Missouri (Mizzou, MU, or Missouri) is a public university, public Land-grant university, land-grant research university in Columbia, Missouri. It is Missouri's largest university and the flagship of the four-campus University of Missouri System. MU was founded in 1839 and was the first public university west of the Mississippi River. It has been a member of the Association of American Universities since 1908 and is classified among "R1: Doctoral Universities – Very high research activity". To date, the University of Missouri alumni, faculty, and staff include 18 Rhodes Scholars, 19 Truman Scholars, 141 Fulbright Scholars, 7 Governors of Missouri, and 6 members of the U.S. Congress. Enrolling 31,401 students in 2021, it offers more than 300 degree programs in thirteen major academic divisions. Its well-known Missouri School of Journalism was founded by Walter Williams (journalist), Walter Williams in 1908 as the world's first journalism school; It publishes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sudden Unexpected Death In Epilepsy
Sudden unexpected death in epilepsy (SUDEP) is a fatal complication of epilepsy. It is defined as the sudden and unexpected, non-traumatic and non-drowning death of a person with epilepsy, without a toxicological or anatomical cause of death detected during the post-mortem examination. While the mechanisms underlying SUDEP are still poorly understood, it is possibly the most common cause of death as a result of complications from epilepsy, accounting for between 7.5 and 17% of all epilepsy-related deaths and 50% of all deaths in refractory epilepsy. The causes of SUDEP seem to be multifactorial and include respiratory, cardiac and cerebral factors as well as the severity of epilepsy and seizures. Proposed pathophysiological mechanisms include seizure-induced cardiac and respiratory arrests. SUDEP occurs in about 1 in 1,000 adults and 1 in 4,500 children with epilepsy a year. Rates of death as a result of prolonged seizures (status epilepticus) are not classified as SUDEP. Cat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serotonin
Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction. Approximately 90% of the serotonin that the body produces is in the intestinal tract. Biochemically, the indoleamine molecule derives from the amino acid tryptophan, via the (rate-limiting) hydroxylation of the 5 position on the ring (forming the intermediate 5-hydroxytryptophan), and then decarboxylation to produce serotonin. Serotonin is primarily found in the enteric nervous system located in the gastrointestinal tract (GI tract). However, it is also produced in the central nervous system (CNS), specifically in the raphe nuclei located in the brainstem, Merkel cells located in the skin, pulmonary neuroendocrine cells and taste receptor cells in the tongue. Additionally, serotonin is stored in blood platelets and is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenosine
Adenosine ( symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9-glycosidic bond. Adenosine is one of the four nucleoside building blocks of RNA (and its derivative deoxyadenosine is a building block of DNA), which are essential for all life. Its derivatives include the energy carriers adenosine mono-, di-, and triphosphate, also known as AMP/ADP/ATP. Cyclic adenosine monophosphate (cAMP) is pervasive in signal transduction. Adenosine is used as an intravenous medication for some cardiac arrhythmias. Adenosyl (abbreviated Ado or 5'-dAdo) is the chemical group formed by removal of the 5′-hydroxy (OH) group. It is found in adenosylcobalamin (an active form of vitamin B12) and as a radical in radical SAM enzymes. Medical uses Supraventricular tachycardia In individuals with supraventricular tachycardia (SVT), adenosine is used to help identify and convert the rhyt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Selective Serotonin Reuptake Inhibitors
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the presynaptic cell. They have varying degrees of selectivity for the other monoamine transporters, with pure SSRIs having strong affinity for the serotonin transporter and only weak affinity for the norepinephrine and dopamine transporters. SSRIs are the most widely prescribed antidepressants in many countries. The efficacy of SSRIs in mild or moderate cases of depression has been disputed and may or may not be outweighed by side effects, especially in adolescent populations. Medical uses The main indication for SSRIs is major depressive disorder; however, they are frequently prescribed for anxiety disorders, such as social anxiety disorder, ge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hal Blumenfeld
Hal Blumenfeld (born March 28, 1962) is a Professor of Neurology, Neuroscience, and Neurosurgery at Yale University. He is an expert on brain mechanisms of consciousness and on altered consciousness in epilepsy. As director of the Yale Clinical Neuroscience Imaging Center (CNIC) he leads multi-disciplinary research and is also well known for his teaching contributions in neuroanatomy and clinical neuroscience. Biography Blumenfeld was born in California, grew up in New York and began his career in Bioelectrical Engineering at Harvard University (1984).Curriculum Vitae. Blumenfeld, H. (Accessed 20 May 2021). https://prod.admin.profile.yale.edu/Profiles/Cv/user/hal_blumenfeld His passion for science would lead him to Columbia University where, working with Eric Kandel and Steven Siegelbaum, he obtained his PhD (1990) in Physiology and Cellular Biophysics and his MD (1992). He completed his internal medicine internship at Columbia Presbyterian Medical Center(1993) and entered the fi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Southern Illinois University
Southern Illinois University is a system of public universities in the southern region of the U.S. state of Illinois. Its headquarters is in Carbondale, Illinois. Board of trustees The university is governed by the nine member SIU Board of Trustees. Seven members are appointed by the governor and confirmed by the state senate. Two members are elected by the student bodies of the Carbondale and Edwardsville campuses. Southern Illinois University Carbondale Founded in Carbondale in 1869 as Southern Illinois Normal College, Southern Illinois University Carbondale (SIUC, usually referred to as SIU) is the flagship campus of the Southern Illinois University system and is the third oldest of Illinois's twelve state universities. SIUC includes six colleges: the College of Agricultural, Life, and Physical Sciences (CALPS), the College of Arts and Media (CAM), the College of Business and Analytics (CoBA), the College of Engineering, Computing, Technology, and Mathematics (CoECTM) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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