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Canine Distemper
Canine distemper virus (CDV) (sometimes termed footpad disease) is a viral disease that affects a wide variety of mammal families, including domestic and wild species of dogs, coyotes, foxes, pandas, wolves, ferrets, skunks, raccoons, and felines, as well as pinnipeds, some primates, and a variety of other species. CDV does not affect humans. In canines CDV affects several body systems, including the gastrointestinal and respiratory tracts and the spinal cord and brain. Common symptoms include high fever, eye inflammation and eye/nose discharge, labored breathing and coughing, vomiting and diarrhea, loss of appetite and lethargy, and hardening of nose and footpads. The viral infection can be accompanied by secondary bacterial infections and can present eventual serious neurological symptoms. Canine distemper is caused by a single-stranded RNA virus of the family ''Paramyxoviridae'' (the same family of the viruses that causes measles, mumps, and bronchiolitis in humans). The d ...
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Canine Distemper
Canine distemper virus (CDV) (sometimes termed footpad disease) is a viral disease that affects a wide variety of mammal families, including domestic and wild species of dogs, coyotes, foxes, pandas, wolves, ferrets, skunks, raccoons, and felines, as well as pinnipeds, some primates, and a variety of other species. CDV does not affect humans. In canines CDV affects several body systems, including the gastrointestinal and respiratory tracts and the spinal cord and brain. Common symptoms include high fever, eye inflammation and eye/nose discharge, labored breathing and coughing, vomiting and diarrhea, loss of appetite and lethargy, and hardening of nose and footpads. The viral infection can be accompanied by secondary bacterial infections and can present eventual serious neurological symptoms. Canine distemper is caused by a single-stranded RNA virus of the family ''Paramyxoviridae'' (the same family of the viruses that causes measles, mumps, and bronchiolitis in humans). The d ...
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Carnivora
Carnivora is a Clade, monophyletic order of Placentalia, placental mammals consisting of the most recent common ancestor of all felidae, cat-like and canidae, dog-like animals, and all descendants of that ancestor. Members of this group are formally referred to as carnivorans, and have evolved to specialize in eating flesh. The order is the fifth largest order of mammals, comprising at least 279 species. Carnivorans live on every major landmass and in a variety of habitats, ranging from the cold polar regions to the hyper-arid region of the Sahara Desert to the open seas. They come in a very large array of different body plans in contrasting shapes and sizes. Carnivora can be divided into two subclades: the cat-like Feliformia and the dog-like Caniformia, which are differentiated based on the structure of their ear bones and cranial features. The feliforms include families such as the felidae, cats, the hyenas, the mongooses and the viverridae, civets. The majority of felifor ...
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Black-footed Ferret
The black-footed ferret (''Mustela nigripes''), also known as the American polecatHeptner, V. G. (Vladimir Georgievich); Nasimovich, A. A; Bannikov, Andrei Grigorovich; Hoffmann, Robert S. (2001)''Mammals of the Soviet Union''Volume: v. 2, pt. 1b. Washington, D.C. : Smithsonian Institution Libraries and National Science Foundation. or prairie dog hunter, is a species of mustelid native to central North America. The black-footed ferret is roughly the size of a mink and is similar in appearance to the European polecat and the Asian steppe polecat. It is largely nocturnal and solitary, except when breeding or raising litters. Up to 90% of its diet is composed of prairie dogs. The species declined throughout the 20th century, primarily as a result of decreases in prairie dog populations and sylvatic plague. It was declared extinct in 1979, but a residual wild population was discovered in Meeteetse, Wyoming in 1981. A captive-breeding program launched by the United States Fish and W ...
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Ailuridae
Ailuridae is a family in the mammal order Carnivora. The family consists of the red panda (the sole living representative) and its extinct relatives. Georges Cuvier first described ''Ailurus'' as belonging to the raccoon family in 1825; this classification has been controversial ever since. It was classified in the raccoon family because of morphological similarities of the head, colored ringed tail, and other morphological and ecological characteristics. Somewhat later, it was assigned to the bear family. Molecular phylogenetic studies had shown that, as an ancient species in the order Carnivora, the red panda is relatively close to the American raccoon and may be either a monotypic family or a subfamily within the procyonid family. An in-depth mitochondrial DNA population analysis study stated: "According to the fossil record, the Red Panda diverged from its common ancestor with bears about 40 million years ago." With this divergence, by comparing the sequence difference betw ...
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Homologous Recombination
Homologous recombination is a type of genetic recombination in which genetic information is exchanged between two similar or identical molecules of double-stranded or single-stranded nucleic acids (usually DNA as in cellular organisms but may be also RNA in viruses). Homologous recombination is widely used by cells to accurately DNA repair harmful breaks that occur on both strands of DNA, known as double-strand breaks (DSB), in a process called homologous recombinational repair (HRR). Homologous recombination also produces new combinations of DNA sequences during meiosis, the process by which eukaryotes make gamete cells, like sperm and egg cells in animals. These new combinations of DNA represent genetic variation in offspring, which in turn enables populations to adapt during the course of evolution. Homologous recombination is also used in horizontal gene transfer to exchange genetic material between different strains and species of bacteria and viruses. Horizontal ...
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Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ultimate source o ...
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Rinderpest
Rinderpest (also cattle plague or steppe murrain) was an infectious viral disease of cattle, domestic buffalo, and many other species of even-toed ungulates, including gaurs, buffaloes, large antelope, deer, giraffes, wildebeests, and warthogs. The disease was characterized by fever, oral erosions, diarrhea, lymphoid necrosis, and high mortality. Death rates during outbreaks were usually extremely high, approaching 100% in immunologically naïve populations. Rinderpest was mainly transmitted by direct contact and by drinking contaminated water, although it could also be transmitted by air. After a global eradication campaign starting in the mid-20th century, the last confirmed case of rinderpest was diagnosed in 2001. On 14 October 2010, the United Nations Food and Agriculture Organization (FAO) announced that field activities in the decades-long, worldwide campaign to eradicate the disease were ending, paving the way for a formal declaration in June 2011 of the global eradica ...
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Phylogenetic Tree Of Paramixoviruses With CDV
In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups of organisms. These relationships are determined by Computational phylogenetics, phylogenetic inference methods that focus on observed heritable traits, such as DNA sequences, protein amino acid sequences, or morphology. The result of such an analysis is a phylogenetic tree—a diagram containing a hypothesis of relationships that reflects the evolutionary history of a group of organisms. The tips of a phylogenetic tree can be living taxa or fossils, and represent the "end" or the present time in an evolutionary lineage. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the tree. An unrooted tree diagram (a network) makes no assumption about the ancestral line, and does n ...
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Enamel Hypoplasia
Enamel hypoplasia is a defect of the teeth in which the enamel is deficient in quantity, caused by defective enamel matrix formation during enamel development, as a result of inherited and acquired systemic condition(s). It can be identified as missing tooth structure and may manifest as pits or grooves in the crown of the affected teeth, and in extreme cases, some portions of the crown of the tooth may have no enamel, exposing the dentin. It may be generalized across the dentition or localized to a few teeth. Defects are categorized by shape or location. Common categories are pit-form, plane-form, linear-form, and localised enamel hypoplasia. Hypoplastic lesions are found in areas of the teeth where the enamel was being actively formed during a systemic or local disturbance. Since the formation of enamel extends over a long period of time, defects may be confined to one well-defined area of the affected teeth. Knowledge of chronological development of deciduous and permanent ...
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Kennel Cough
Kennel cough, also known as canine infectious respiratory disease, formally canine infectious tracheobronchitis, is an upper respiratory infection affecting dogs. There are multiple causative agents, the most common being the bacterium ''Bordetella bronchiseptica'' (found in 78.7% of cases in Southern Germany), followed by canine parainfluenza virus (37.7% of cases), and to a lesser extent canine coronavirus (9.8% of cases). It is highly contagious; however, adult dogs may display immunity to reinfection even under constant exposure. Kennel cough is so named because the infection can spread quickly among dogs in the close quarters of a kennel or animal shelter. Viral and bacterial causes of canine cough are spread through airborne droplets produced by sneezing and coughing. These agents also spread through contact with contaminated surfaces. Symptoms begin after a several day incubation period post-exposure, and in most cases will clear up on their own. However, in young puppie ...
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Pinniped
Pinnipeds (pronounced ), commonly known as seals, are a widely distributed and diverse clade of carnivorous, fin-footed, semiaquatic, mostly marine mammals. They comprise the extant families Odobenidae (whose only living member is the walrus), Otariidae (the eared seals: sea lions and fur seals), and Phocidae (the earless seals, or true seals). There are 34 extant species of pinnipeds, and more than 50 extinct species have been described from fossils. While seals were historically thought to have descended from two ancestral lines, molecular evidence supports them as a monophyletic lineage (descended from one ancestral line). Pinnipeds belong to the order Carnivora; their closest living relatives are musteloids (weasels, raccoons, skunks, and red pandas), having diverged about 50 million years ago. Seals range in size from the and Baikal seal to the and southern elephant seal male, which is also the largest member of the order Carnivora. Several species exh ...
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