Creatine Kinase
Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme () expressed by various tissues and cell types. CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). This CK enzyme reaction is reversible and thus ATP can be generated from PCr and ADP. In tissues and cells that consume ATP rapidly, especially skeletal muscle, but also brain, photoreceptor cells of the retina, hair cells of the inner ear, spermatozoa and smooth muscle, PCr serves as an energy reservoir for the rapid buffering and regeneration of ATP ''in situ'', as well as for intracellular energy transport by the PCr shuttle or circuit. Thus creatine kinase is an important enzyme in such tissues. Clinically, creatine kinase is assayed in blood tests as a marker of damage of CK-rich tissue such as in myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cytokeratin
Cytokeratins are keratin proteins found in the intracytoplasmic cytoskeleton of epithelial tissue. They are an important component of intermediate filaments, which help cells resist mechanical stress. Expression of these cytokeratins within epithelial cells is largely specific to particular organs or tissues. Thus they are used clinically to identify the cell of origin of various human tumors. Naming The term ''cytokeratin'' began to be used in the late 1970s, when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. In 2006 a new systematic nomenclature for mammalian keratins was created, and the proteins previously called ''cytokeratins'' are simply called ''keratins'' (human epithelial category). For example, cytokeratin-4 (CK-4) has been renamed keratin-4 (K4). However, they are still commonly referred to as cytokeratins in clinical practice. Types There are two categories of cytokeratins: the acidic type I cyt ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Collective Knowledge (software)
The Collective Knowledge (CK) project is an open-source framework and repository to enable collaborative, reproducible and sustainable research and development of complex computational systems. CK is a small, portable, customizable and decentralized infrastructure helping researchers and practitioners: * share their code, data and models as reusable Python components and automation actions with unified JSON API, JSON meta information, and a UID based on FAIR principles * assemble portable workflows from shared components (such as multi-objective autotuning and Design space exploration) * automate, crowdsource and reproduce benchmarking of complex computational systems * unify predictive analytics (scikit-learn, R, DNN) * enable reproducible and interactive papers Notable usages * ARM uses CK to accelerate computer engineering *Association for Computing Machinery evaluates CK for possible integration with the ACM Digital Library sponsored by the Sloan Foundation and for reprod ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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CK Hutchison Holdings
CK Hutchison Holdings Limited is a Hong Kong-based and Cayman Islands-registered multinational conglomerate corporation. The company was formed in March 2015 through the merger of Cheung Kong Holdings and its main associate company Hutchison Whampoa. It has four core businesses ‐ ports and related services, retail, infrastructure and telecommunications - which operate in over 50 countries, as well as several other investments around the world. Holdings The company owns substantial holdings in businesses across a number of industries. Telecoms The Group’s telecommunications division is a leading global operator and innovator of converged telecommunication and digital services around the world. * CK Hutchison Group Telecom – operates 3-branded mobile telephone networks in Austria, Denmark, Ireland, Sweden and the United Kingdom. * Hutchison Asia Telecom Group – operates mobile telephone networks in Indonesia, Sri Lanka and Vietnam. ** Hutchison Telecommunications Lan ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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C-K Theory
A graphical representation of a Design Process using C-K Design Theory. C-K design theory or concept-knowledge theory is both a design theory and a theory of reasoning in design. It defines design reasoning as a logic of expansion processes, ''i.e.'' a logic that organizes the generation of unknown objects. The theory builds on several traditions of design theory, including systematic design, axiomatic design, creativity theories, general and formal design theories,.Braha D. and Maimon O. 1998. ''A Mathematical Theory of Design: Foundations, Algorithms, and Applications.'' Springer. Claims made for C-K design theory include that it is the first design theory that: # Offers a comprehensive formalization of design that is independent of any design domain or object # Explains invention, creation, and discovery within the same framework as design processes. The name of the theory is based on its central premises: the distinction between two spaces: *a space of concepts C *a space ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cyanogen Chloride
Cyanogen chloride is a highly toxic chemical compound with the formula CNCl. This linear, triatomic pseudohalogen is an easily condensed colorless gas. More commonly encountered in the laboratory is the related compound cyanogen bromide, a room-temperature solid that is widely used in biochemical analysis and preparation. Synthesis, basic properties, structure Cyanogen chloride is a molecule with the connectivity . Carbon and chlorine are linked by a single bond, and carbon and nitrogen by a triple bond. It is a linear molecule, as are the related cyanogen halides (NCF, NCBr, NCI). Cyanogen chloride is produced by the oxidation of sodium cyanide with chlorine. This reaction proceeds via the intermediate cyanogen (). :NaCN + Cl2 -> ClCN + NaCl The compound trimerizes in the presence of acid to the heterocycle called cyanuric chloride. Cyanogen chloride is slowly hydrolyzed by water at neutral pH to release cyanate and chloride ions: :ClCN + H2O -> NCO- + Cl- + 2H+ Applicatio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Composite Corridor
The Composite Corridor (or CK) is a railway coach with a number of compartments, some of which are standard class (previously second, né third class) and some first class, linked by a side corridor. History The composite coach was a standard coach design going back to the early days of railways, enabling a railway company to provide multi-class passenger accommodation in a single vehicle and so reduce costs. In the book "Red For Danger" by L.T.C Rolt it is mentioned that the train which came to grief at Wigan on the night of 2 August 1873 featured a Caledonian Railway composite coach. Early composite coaches did not feature corridors or gangways between the vehicles. Gangwayed stock Once communicating gangways between coaches were introduced, a side corridor was provided to allow passengers and staff to walk up and down the train, while seated passengers in compartments were not disturbed, and thus the various types of side-corridor coaches were developed. Non-gangwayed st ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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China Cargo Airlines
China Cargo Airlines () sometimes as abbreviated 中货航 (in English as ''CCA'') is a cargo airline with its head office on Hongqiao International Airport in Shanghai, People's Republic of China. It is China's first all-cargo airline operating dedicated freight services using China Eastern Airlines route structure. Its base is at Shanghai Hongqiao International Airport, with a hub at Shanghai Pudong International Airport. History The airline was established on 30 July 1998 and started operations in October 1998. It was founded as, and remains, a joint venture between China Eastern Airlines (70%) and China Ocean Shipping (30%). It briefly adopted the title China Eastern Airlines Cargo, and reverted to its original name again after becoming an independent subsidiary in 2004. Its parent company China Eastern Airlines reached agreement to inject more capital into the cargo airline. Its stake fell from 70 percent to just over 51 percent. China Ocean Shipping's share reduced to 17 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chevrolet C/K
C/K is a series of trucks that was manufactured by General Motors from the 1960 to 2002 model years. Marketed by both the Chevrolet and GMC divisions, the C/K series encompassed a wide range of vehicles. While most commonly associated with pickup trucks, the model line also included chassis-cab trucks and medium-duty trucks and served as the basis for GM full-size SUVs. Through its entire production, the model line competed directly against the Ford F-Series and the Dodge D series (later the Dodge Ram pickup). Used for both the model branding and the internal model code, "C" denoted two-wheel drive; "K" denoted four-wheel drive. Four generations of the model line were produced, including the second-generation "Action Line" and third-generation "Rounded Line" vehicles. For the fourth generation, GMC revised its branding, changing to a singular GMC Sierra nameplate (C/K remained as an internal model code). For South America, the model line was manufactured by General Motors ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Circle K
Circle K Stores, Inc. is a Canadian chain of convenience stores headquartered in Laval, Quebec, Canada. It is owned by the multinational company Couche-Tard. Founded in 1951 in El Paso, Texas, the company filed for bankruptcy protection in 1990 and went through several owners, before being acquired by Alimentation Couche-Tard in 2003. As of February 2020, Circle K has 9,799 stores in North America, 2,697 stores in Europe, and an additional 2,380 stores operating under franchise agreements worldwide. In 2015, Circle K unveiled a new logo and brand identity, and Couche-Tard announced that it would deploy the brand globally, including English-speaking Canada (rebranding from the Mac's brand), Europe (rebranding from the Statoil brand), and the United States (rebranding from the Kangaroo Express brand and updating the existing Circle K brand). Overview Since the 1980s, Circle K has been the largest chain of company-owned and operated (non-franchised) convenience stores in the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cranbrook Kingswood
Cranbrook Schools is a private, PK–12 preparatory school located on a campus in Bloomfield Hills, Michigan. The schools comprise a co-educational elementary school, a middle school with separate schools for boys and girls, and a co-educational high school with boarding facilities. Cranbrook Schools is part of the Cranbrook Educational Community (CEC), which includes the Cranbrook Institute of Science, the Cranbrook Academy of Art, and Cranbrook House and Gardens. (Nearby Christ Church Cranbrook remains outside this formal structure.) The Cranbrook community was established by publishing mogul George Booth, who bought the site of today's Cranbrook community in 1904. Cranbrook was designated a National Historic Landmark on June 29, 1989 for its significant architecture and design. It attracts tourists from around the world. Approximately of Cranbrook Schools' campus are gardens. As of 2015, Cranbrook Schools had an endowment of $233 million, among the fifteen largest held by ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Core Knowledge
Core Knowledge (CK) refers to a current textbook series originally written by a collective of former top Year 12 South Australian students of the same name (2003–2008) for South Australian Certificate of Education (SACE) students. The Core Knowledge group was the first student collective of its type and magnitude in Australia, recruiting top students from 13 schools across South Australia since 2003. Unlike other similar resources, the Core Knowledge subject guides incorporated a unique student perspective, earning praise from the Australian National Innovation Council in 2005 and students and reviewers from South Australia, Victoria, NSW, Singapore, Malaysia and Indonesia. As of 2007, the resources available include Maths Studies, Biology, Physics and Chemistry subject guides. Writers include former top students from Annesley College, Eynesbury Senior College, Glenunga International High School, Marryatville High School, Norwood Morialta High School, Prince Alfred College, Pem ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |