C12orf60
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C12orf60
Uncharacterized protein C12orf60 is a protein that in humans (''Homo sapiens'') is encoded by the ''C12orf60'' gene. The gene is also known as ''LOC144608'' or ''MGC47869''. The protein lacks transmembrane domains and helices, but it is rich in Alpha helix, alpha-helices. It is predicted to localize in the nucleus. The ''C12orf60'' mature Messenger RNA, mRNA transcript is 1139 nucleotides long and encodes a protein containing 245 amino acids. The protein lacks transmembrane domains and helices, but it is rich in Alpha helix, alpha-helices. It is predicted to localize in the nucleus, but its function is not yet well understood by the scientific community. The gene was listed as a potential biomarker for detecting the efficacy of allergen immunotherapy.Hiroi, T., & Okubo, K. (2010). ''U.S. Patent Application No. 13/498,267''. The gene is highly expressed in the Testicle, testes and Large intestine, colon, but it is also expressed in the kidney, Breast cancer, breast carcinomas, brai ...
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SMCO3
Single-pass membrane and coiled-coil domain-containing protein 3 is a protein that is encoded in humans by the ''SMCO3'' gene. Gene Aliases ''SMCO3'' has 2 aliases, C12orf69 and LOC440087. Location ''SMCO3'' is located on the negative strand of chromosome 12 (12p12.3) and spans 10,460 base pairs (chr12:14,803,723-14,814,182). It has 2 exons that flank a single intron. Gene Neighborhood ''SMCO3'' is flanked by WW domain binding protein 1-like, WW domain binding protein 11 (WBP11) and ART4, Ecto-ADP-ribosyltransferase 4 (ART4) on the minus strand and overlaps with C12orf60 on the plus strand. There is only a single isoform of this gene. Expression ''SMCO3'' is expressed in very low levels in several different human tissues including cervix, connective tissue, eye, lung and prostate. This highest expression of ''SMCO3'' is seen in the kidney, liver and spleen. ''SMCO3'' is also expressed at higher levels in cancers, especially chondrosarcoma and Clear cell renal cell c ...
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