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C-Repeat Binding Factor
C-Repeat Binding Factors (CBFs) are transcription factor In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The fu ...s in plants involved in response to low temperature. Also known as Dehydration Response Element Binding factors (DREBs), they are a subfamily of AP2 DNA binding domain transcription factors. References * Stockinger, E. J., Gilmour, S. J. & Thomashow, M.F. (1997) Proc. Natl. Acad. Sci. USA 94, 1035–1040 * Liu, Q., Kasuga, M., Sakuma, Y., Abe, H., Miura, S., Yamaguchi-Shinozaki, K. & Shinozaki, K. (1998) Plant Cell 10, 1391–1406 * Jaglo-Ottosen, K. R., Gilmour, S. J., Zarka, D. G., Schabenberger, O. & Thomashow, M. F. (1998) Science 280, 104–106 Transcription factors {{botany-stub ...
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Transcription Factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The function of TFs is to regulate—turn on and off—genes in order to make sure that they are expressed in the desired cells at the right time and in the right amount throughout the life of the cell and the organism. Groups of TFs function in a coordinated fashion to direct cell division, cell growth, and cell death throughout life; cell migration and organization (body plan) during embryonic development; and intermittently in response to signals from outside the cell, such as a hormone. There are up to 1600 TFs in the human genome. Transcription factors are members of the proteome as well as regulome. TFs work alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of RNA ...
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