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C.H. Waddington
Conrad Hal Waddington (8 November 1905 – 26 September 1975) was a British developmental biologist, paleontologist, geneticist, embryologist and philosopher who laid the foundations for systems biology, epigenetics, and evolutionary developmental biology. Although his theory of genetic assimilation had a Darwinian explanation, leading evolutionary biologists including Theodosius Dobzhansky and Ernst Mayr considered that Waddington was using genetic assimilation to support so-called Lamarckian inheritance, the acquisition of inherited characteristics through the effects of the environment during an organism's lifetime. Waddington had wide interests that included poetry and painting, as well as left-wing political leanings. In his book ''The Scientific Attitude'' (1941), he touched on political topics such as central planning, and praised Marxism as a "profound scientific philosophy". Life Conrad Waddington, known as "Wad" to his friends and "Con" to family, was born in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evesham
Evesham () is a market town and parish in the Wychavon district of Worcestershire, in the West Midlands region of England. It is located roughly equidistant between Worcester, Cheltenham and Stratford-upon-Avon. It lies within the Vale of Evesham, an area comprising the flood plain of the River Avon, which has been renowned for market gardening. The town centre, situated within a meander of the river, is subjected regularly to flooding. The 2007 floods were the most severe in recorded history. The town was founded around an 8th-century abbey, one of the largest in Europe, which was destroyed during the Dissolution of the Monasteries, with only Abbot Lichfield's Bell Tower remaining. During the 13th century, one of the two main battles of England's Second Barons' War took place near the town, marking the victory of Prince Edward, who later became King Edward I; this was the Battle of Evesham. History Evesham is derived from the Old English ''homme'' or ''ham'', and ''Eof'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Justin Blanco White
Margaret Justin Blanco White OBE ARIBA (11 December 1911 – 1 November 2001) was a Scottish architect. Early life and education Margaret Justin Blanco White was born at 30 Pembroke Square, Kensington, London, on 11 December 1911. Her father was George Rivers Blanco White KC, and her mother was writer Amber Reeves. Her brother was Thomas Blanco White, an intellectual property lawyer. She had an older half sibling Anna-Jane whose father was H.G. Wells. Her maternal grandparent were William Pember Reeves and Maud Pember Reeves. She was educated at St Paul’s Girls’ School, London between 1926 and 1929. Blanco White trained at the Architectural Association School of Architecture from 1929, alongside students and close friends Judith Ledeboer, Jessica Albery, and Mary Crowley (later Medd), where they developed a commitment to housing reform and social concerns which impacted their later careers. Career Justin Blanco White designed Shawms, Conduit Head Road, Cambridge i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernst Mayr
Ernst Walter Mayr (; 5 July 1904 – 3 February 2005) was one of the 20th century's leading evolutionary biologists. He was also a renowned Taxonomy (biology), taxonomist, tropical explorer, ornithologist, Philosophy of biology, philosopher of biology, and History of science, historian of science. His work contributed to the conceptual revolution that led to the Modern synthesis (20th century), modern evolutionary synthesis of Gregor Mendel, Mendelian genetics, systematics, and Charles Darwin, Darwinian evolution, and to the development of the Species, biological species concept. Although Charles Darwin and others posited that multiple species could evolve from a single common ancestor, the mechanism by which this occurred was not understood, creating the ''species problem''. Ernst Mayr approached the problem with a new definition for species. In his book ''Systematics and the Origin of Species'' (1942) he wrote that a species is not just a group of Morphology (biology), morph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Theodosius Dobzhansky
Theodosius Grigorievich Dobzhansky (russian: Феодо́сий Григо́рьевич Добржа́нский; uk, Теодо́сій Григо́рович Добржа́нський; January 25, 1900 – December 18, 1975) was a prominent Russian-American geneticist and evolutionary biologist, and a central figure in the field of evolutionary biology for his work in shaping the modern synthesis. Born in the Russian Empire, Dobzhansky emigrated to the United States in 1927, aged 27. He was a distant relation of the Russian writer Feodor Dostoevsky. His 1937 work ''Genetics and the Origin of Species'' became a major influence on the modern synthesis. He was awarded the US National Medal of Science in 1964 and the Franklin Medal in 1973. Biography Early life Dobzhansky was born on January 25, 1900, in Nemirov, Russian Empire (now Nemyriv, Ukraine), the only child of Grigory Dobzhansky, a mathematics teacher, and Sophia Voinarsky. He was given a rare name, Theodosius, bec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolutionary Biology
Evolutionary biology is the subfield of biology that studies the evolutionary processes (natural selection, common descent, speciation) that produced the diversity of life on Earth. It is also defined as the study of the history of life forms on Earth. Evolution is based on the theory that all species are related and they gradually change over time. In a population, the genetic variations affect the physical characteristics i.e. phenotypes of an organism. These changes in the phenotypes will be an advantage to some organisms, which will then be passed onto their offspring. Some examples of evolution in species over many generations are the Peppered Moth and Flightless birds. In the 1930s, the discipline of evolutionary biology emerged through what Julian Huxley called the modern synthesis of understanding, from previously unrelated fields of biological research, such as genetics and ecology, systematics, and paleontology. The importance of studying Evolutionary biology is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Darwinian
Darwinism is a theory of biological evolution developed by the English naturalist Charles Darwin (1809–1882) and others, stating that all species of organisms arise and develop through the natural selection of small, inherited variations that increase the individual's ability to compete, survive, and reproduce. Also called Darwinian theory, it originally included the broad concepts of transmutation of species or of evolution which gained general scientific acceptance after Darwin published ''On the Origin of Species'' in 1859, including concepts which predated Darwin's theories. English biologist Thomas Henry Huxley coined the term ''Darwinism'' in April 1860. Terminology Darwinism subsequently referred to the specific concepts of natural selection, the Weismann barrier, or the central dogma of molecular biology. Though the term usually refers strictly to biological evolution, creationists have appropriated it to refer to the origin of life or to cosmic evolution, that are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolutionary Developmental Biology
Evolutionary developmental biology (informally, evo-devo) is a field of biological research that compares the developmental processes of different organisms to infer how developmental processes evolved. The field grew from 19th-century beginnings, where embryology faced a mystery: zoologists did not know how embryonic development was controlled at the molecular level. Charles Darwin noted that having similar embryos implied common ancestry, but little progress was made until the 1970s. Then, recombinant DNA technology at last brought embryology together with molecular genetics. A key early discovery was of homeotic genes that regulate development in a wide range of eukaryotes. The field is composed of multiple core evolutionary concepts. One is deep homology, the finding that dissimilar organs such as the eyes of insects, vertebrates and cephalopod molluscs, long thought to have evolved separately, are controlled by similar genes such as ''pax-6'', from the evo-devo gene toolk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epigenetics
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the mechanism of changes: functionally relevant alterations to the genome that do not involve mutation of the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. Particularly from the year 2000 onwards, the concept has been used widely in biology in a variety of contexts. The Human Genome Project is an example of applied systems thinking in biology which has led to new, collaborative ways of working on problems in the biological field of genetics. One of the aims of systems biology is to model and discover emergent property, emergent properties, properties of cell (biology), cells, tissue (biology), tissues and organisms functioning as a system whose theoretical description is only possible using techniques of systems biology. These typically involve metabolic networks or cell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philosopher
A philosopher is a person who practices or investigates philosophy. The term ''philosopher'' comes from the grc, φιλόσοφος, , translit=philosophos, meaning 'lover of wisdom'. The coining of the term has been attributed to the Greek thinker Pythagoras (6th century BCE).. In the Classics, classical sense, a philosopher was someone who lived according to a certain way of life, focusing upon resolving Meaning of life, existential questions about the human condition; it was not necessary that they discoursed upon Theory, theories or commented upon authors. Those who most arduously committed themselves to this lifestyle would have been considered ''philosophers''. In a modern sense, a philosopher is an intellectual who contributes to one or more branches of philosophy, such as aesthetics, ethics, epistemology, philosophy of science, logic, metaphysics, social theory, philosophy of religion, and political philosophy. A philosopher may also be someone who has worked in the hum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embryologist
Embryology (from Greek ἔμβρυον, ''embryon'', "the unborn, embryo"; and -λογία, '' -logia'') is the branch of animal biology that studies the prenatal development of gametes (sex cells), fertilization, and development of embryos and fetuses. Additionally, embryology encompasses the study of congenital disorders that occur before birth, known as teratology. Early embryology was proposed by Marcello Malpighi, and known as preformationism, the theory that organisms develop from pre-existing miniature versions of themselves. Aristotle proposed the theory that is now accepted, epigenesis. Epigenesis is the idea that organisms develop from seed or egg in a sequence of steps. Modern embryology, developed from the work of Karl Ernst von Baer, though accurate observations had been made in Italy by anatomists such as Aldrovandi and Leonardo da Vinci in the Renaissance. Comparative embryology Preformationism and epigenesis As recently as the 18th century, the prevailin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Geneticist
A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic processes or develop genetic technologies to aid in the pharmaceutical or and agriculture industries. Some geneticists perform experiments in model organisms such as ''Drosophila'', ''C. elegans'', zebrafish, rodents or humans and analyze data to interpret the inheritance of biological traits. A basic science geneticist is a scientist who usually has earned a PhD in genetics and undertakes research and/or lectures in the field. A medical geneticist is a physician who has been trained in medical genetics as a specialization and evaluates, diagnoses, and manages patients with hereditary conditions or congenital malformations; and provides genetic risk calculations and mutation analysis. Education Geneticists participate in courses from many are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
