Burow's Solution
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Burow's Solution
Burow's solution is an aqueous solution of aluminium triacetate. It is available in the U.S. as an over-the-counter drug for topical administration, with brand names including Domeboro (Moberg Pharma), Domeboro Otic (ear drops), Star-Otic, and Borofair. The preparation has astringent and antibacterial properties and may be used to treat a number of skin conditions, including insect bites and stings, rashes caused by poison ivy and poison sumac, swelling, allergies, and bruises. However, its main use is for treatment of otitis (ear infection), including otomycosis (fungal ear infection). History The creator of Burow's solution was Karl August Burow (1809-1874), a military surgeon and anatomist. Burow was also the inventor of some plastic surgery and wound healing techniques which are still in wide use today. Use Otitis Burow's solution may be used to treat various forms of ear infections, known as otitis. As a drug it is inexpensive and non-ototoxic. In cases of otomycosis it i ...
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Aqueous Solution
An aqueous solution is a solution in which the solvent is water. It is mostly shown in chemical equations by appending (aq) to the relevant chemical formula. For example, a solution of table salt, or sodium chloride (NaCl), in water would be represented as . The word ''aqueous'' (which comes from ''aqua'') means pertaining to, related to, similar to, or dissolved in, water. As water is an excellent solvent and is also naturally abundant, it is a ubiquitous solvent in chemistry. Since water is frequently used as the solvent in experiments, the word solution refers to an aqueous solution, unless the solvent is specified. A ''non-aqueous solution'' is a solution in which the solvent is a liquid, but is not water. (See also Solvent and Inorganic nonaqueous solvent.) Characteristics Substances that are ''hydrophobic'' ('water-fearing') do not dissolve well in water, whereas those that are ''hydrophilic'' ('water-friendly') do. An example of a hydrophilic substance is sodium chl ...
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Otitis
Otitis is a general term for inflammation or infection, inner ear infection, middle ear infection of the ear, in both humans and other animals. When infection is present, it may be viral or bacterial. When inflammation is present due to fluid build up in the middle ear and infection is not present it is considereOtitis media with effusion It is subdivided into the following: * '' Otitis externa'', external otitis, or "swimmer's ear", involves the outer ear and ear canal. In external otitis, we see tenderness in the pinna—i.e., the outer ear hurts when touched or pulled. * ''Otitis media'', or middle ear infection, involves the middle ear. In otitis media, the ear is infected or clogged with fluid behind the ear drum, in the normally air-filled middle-ear space. This is the most common infection and very common in babies below 6 months. This condition sometimes requires a surgical procedure called '' myringotomy'' and tube insertion. * '' Otitis interna'', or labyrinthitis, ...
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Anti-itch Drug
Antipruritics, abirritants, or anti-itch drugs, are medications that inhibit the itching (Latin: ''pruritus'') often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, and mites, and contact dermatitis and urticaria caused by plants such as poison ivy ( urushiol-induced contact dermatitis) or stinging nettle. It can also be caused by chronic kidney disease and related conditions. Abirritants consist of a large group of drugs belonging to different classes with varying mechanisms to treat itch. They may work either directly or indirectly to relieve itch, and evidence on their effectiveness varies from one class to another. Some alternative medicines are also used to treat itch. Side effects of abirritants also vary depending on the class of the drug. Even before the emergence of modern evidence-based medicine, abirritants have already been used in many civilizations, but practice ...
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Urushiol-induced Contact Dermatitis
Urushiol-induced contact dermatitis (also called Toxicodendron dermatitis or Rhus dermatitis) is a type of allergic contact dermatitis caused by the oil urushiol found in various plants, most notably species of the genus '' Toxicodendron'': poison ivy, poison oak, poison sumac, and the Chinese lacquer tree. The name is derived from the Japanese word for the sap of the Chinese lacquer tree, ''urushi''. Other plants in the sumac family (including mango, pistachio, the Burmese lacquer tree, the India marking nut tree, and the shell of the cashew) also contain urushiol, as do unrelated plants such as ''Ginkgo biloba.'' As is the case with all contact dermatitis, urushiol-induced allergic rashes are a Type IV hypersensitivity reaction, also known as delayed-type hypersensitivity. Symptoms include itching, inflammation, oozing, and, in severe cases, a burning sensation. The American Academy of Dermatology estimates that there are up to 50 million cases of urushiol-induced dermat ...
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Urushiol
Urushiol is an oily mixture of organic compounds with allergenic properties found in plants of the family Anacardiaceae, especially '' Toxicodendron'' ''spp.'' (e.g., poison oak, Chinese lacquer tree, poison ivy, poison sumac), ''Comocladia spp.'' (maidenplums), ''Metopium spp''. (poisonwood), and also in parts of the mango tree as well as the fruit of the cashew tree. In most individuals, urushiol causes an allergic skin rash on contact, known as urushiol-induced contact dermatitis. The name urushiol is derived from the Japanese word for the lacquer tree, . The oxidation and polymerization of urushiol in the tree's sap in the presence of moisture allows it to form a hard lacquer, which is used to produce traditional Chinese, Korean and Japanese lacquerware. History Although urushiol-containing lacquers and their skin-irritating properties were well known in East Asia for several millennia, its first recorded Western texts were in 1624 by John Smith and he initial ...
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Ingrown Nail
An ingrown nail, also known as onychocryptosis from el, ὄνυξ () 'nail' and () 'hidden', is a common form of nail disease. It is an often painful condition in which the nail grows so that it cuts into one or both sides of the paronychium or nail bed. While ingrown nails can occur in the nails of both the hands and the feet, they occur most commonly with the toenails (as opposed to fingernails), and for the most part are only problematic and painful on the big toe. A common conception is that the nail enters into the paronychium, but an "ingrown toenail" can simply be overgrown toe skin. The condition starts first from a microbial inflammation of the paronychium, and then a granuloma, which results in a nail buried inside of the granuloma. A true ''ingrown toenail'' is caused by actual penetration of flesh by a sliver of toenail. Signs and symptoms Symptoms of an ingrown nail include pain along the margins of the nail (caused by hypergranulation that occurs around th ...
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Calcium Acetate Monohydrate
Calcium acetate is a chemical compound which is a calcium salt of acetic acid. It has the formula Ca(C2H3O2)2. Its standard name is calcium acetate, while calcium ethanoate is the systematic name. An older name is acetate of lime. The anhydrous form is very hygroscopic; therefore the monohydrate (Ca(CH3COO)2•H2O) is the common form. Production Calcium acetate can be prepared by soaking calcium carbonate (found in eggshells, or in common carbonate rocks such as limestone or marble) or hydrated lime in vinegar: :CaCO3(s) + 2CH3COOH(aq) → Ca(CH3COO)2(aq) + H2O(l) + CO2(g) :Ca(OH)2(s) + 2CH3COOH(aq) → Ca(CH3COO)2(aq) + 2H2O(l) Since both reagents would have been available pre-historically, the chemical would have been observable as crystals then. Uses * In kidney disease, blood levels of phosphate may rise (called hyperphosphatemia) leading to bone problems. Calcium acetate binds phosphate in the diet to lower blood phosphate levels. * Calcium acetate is used as a food addit ...
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Aluminium Sulfate
Aluminium sulfate is a salt with the formula Al2 (SO4)3. It is soluble in water and is mainly used as a coagulating agent (promoting particle collision by neutralizing charge) in the purification of drinking water and wastewater treatment plants, and also in paper manufacturing. The anhydrous form occurs naturally as a rare mineral millosevichite, found for example in volcanic environments and on burning coal-mining waste dumps. Aluminium sulfate is rarely, if ever, encountered as the anhydrous salt. It forms a number of different hydrates, of which the hexadecahydrate Al2(SO4)3·16H2O and octadecahydrate Al2(SO4)3·18H2O are the most common. The heptadecahydrate, whose formula can be written as l(H2O)6sub>2(SO4)3·5H2O, occurs naturally as the mineral alunogen. Aluminium sulfate is sometimes called alum or papermaker's alum in certain industries. However, the name "alum" is more commonly and properly used for any double sulfate salt with the generic formula , where ''X'' i ...
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Clotrimazole
Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina. Common side effects when taken by mouth include nausea and itchiness. When applied to the skin, common side effects include redness and a burning sensation. In pregnancy, use on the skin or in the vagina is believed to be safe. There is no evidence of harm when used by mouth during pregnancy but this has been less well studied. When used by mouth, greater care should be taken in those with liver problems. It is in the azole class of medications and works by disrupting the fungal cell membrane. Clotrimazole was discovered in 1969. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. Medical uses It ...
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Ototoxicity
Ototoxicity is the property of being toxic to the ear (''oto-''), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. It has been recognized since the 19th century. There are many well-known ototoxic drugs used in clinical situations, and they are prescribed, despite the risk of hearing disorders, for very serious health conditions. Ototoxic drugs include antibiotics (such as gentamicin, streptomycin, tobramycin), loop diuretics (such as furosemide), and platinum-based chemotherapy agents (such as cisplatin and carboplatin). A number of nonsteroidal anti-inflammatory drugs (NSAIDS) have also been shown to be ototoxic. This can result in sensorineural hearing loss, dysequilibrium, or both. Some environmental and occupational chemicals have also been shown to affect the auditory system and interact with noise. Signs and ...
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Karl August Burow
Karl Heinrich August von Burow (10 November 1809 in Elbing – 15 April 1874 in Königsberg) was a German surgeon and ophthalmologist. From 1830 he studied at the University of Königsberg, where his influences included Ludwig Wilhelm Sachs, Karl Ernst von Baer and Karl Friedrich Burdach. In 1839, he obtained his habilitation and in 1844 became an associate professor. In 1846, he opened a private medical clinic in Konigsberg, in which he specialized in ophthalmology and surgery. In 1859, he resigned his professorship and became a ''Sanitätsrat'' (medical officer). In 1866 he was a consultant physician to the army of Edwin Freiherr von Manteuffel, and in 1870 he performed in a similar role to the army of Prince Friedrich Karl of Prussia.ADB:Burow, Karl August
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Otomycosis
Otomycosis is a fungal ear infection, a superficial mycotic infection of the outer ear canal. It is more common in tropical countries. The infection may be either subacute or acute and is characterized by malodorous discharge, inflammation, pruritus, scaling, and severe discomfort. The mycosis results in inflammation, superficial epithelial exfoliation, masses of debris containing hyphae, suppuration, and pain. Diagnosis Otoscopy (exam of the ear) is best done with a binocular microscope that provides adequate lighting, depth perception, and the ability to instrument the ear to comfortably remove the fungus. Findings range from scattered saprophytic fungal colonies of various colors, causing no symptoms, to densely packed fungal debris, often intermixed with cerumen (wax), filling the entire canal and involving the tympanic membrane (eardrum). The fungus can cling to the skin and tympanic membrane, presumably because of invading hyphae, and can require significant ti ...
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