|
Bunyamwera Virus
''Bunyamwera orthobunyavirus'' (BUNV) is a negative-sense, single-stranded enveloped RNA virus. It is assigned to the ''Orthobunyavirus'' genus, in the ''Bunyavirales'' order. ''Bunyamwera orthobunyavirus'' can infect both humans and ''Aedes aegypti'' (yellow fever mosquito). It is named for Bunyamwera, a town in western Uganda, where it was isolated in 1943. Reassortant viruses derived from ''Bunyamwera orthobunyavirus'', such as '' Ngari virus'', have been associated with large outbreaks of viral haemorrhagic fever in Kenya and Somalia. Molecular biology The genetic structure of ''Bunyamwera orthobunyavirus'' is typical for ''Bunyavirales'' viruses, which are an order of enveloped negative-sense, single-stranded RNA viruses with a genome split into three parts—Small (S), Middle (M), and Large (L). The L RNA segment encodes an RNA-dependent RNA polymerase (L protein), the M RNA segment encodes two surface glycoproteins (Gc and Gn) and a nonstructural protein (NSm), whi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Batai Virus
''Batai orthobunyavirus'' (BATV) is a RNA virus belonging to order ''Bunyavirales'', genus ''Orthobunyavirus''. Introduction Batai virus (BATV) is an enveloped, single-stranded, negative sense RNA genome. It is a member of the genus Orthobunyavirus and belongs to the order Bunyavirales; it was first isolated from Culex mosquitoes in Malaysia in 1955. Evidence from serological surveillance and virus isolation shows that this virus is widely distributed around the world. Similar to other orthobunyaviruses it contributes to both human and animal disease. In humans it has been noted in causing severe fever, and in bovines has been associated with premature birth, birth defects, and increased abortion rates. It is transmitted through mosquito bites, ticks, and biting midges, and occurs from cold to tropical regions of Africa, Asia, and Europe. Structure The structure of Batai virus (BATV) consists of an enveloped nucleocapsid that is composed of three RNA segments: small (S), medium ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
