Bundibugyo Virus
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Bundibugyo Virus
The species ''Bundibugyo ebolavirus'' ( ) is the taxonomic home of one virus, Bundibugyo virus (BDBV), that forms filamentous virions and is closely related to the infamous Ebola virus (EBOV). The virus causes severe disease in humans in the form of viral hemorrhagic fever and is a Select agent, World Health Organization Risk Group 4 Pathogen (requiring Biosafety Level 4-equivalent containment), National Institutes of Health/National Institute of Allergy and Infectious Diseases Category A Priority Pathogen, Centers for Disease Control and Prevention Category A Bioterrorism Agent, and is listed as a Biological Agent for Export Control by the Australia Group. Use of term The species ''Bundibugyo ebolavirus'' is a virological taxon (i.e. a man-made concept) that was suggested in 2008 to be included in the genus ''Ebolavirus'', family ''Filoviridae'', order ''Mononegavirales''. The species has a single virus member, Bundibugyo virus (BDBV). The members of the species are called Bu ...
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Ebola Virus
''Zaire ebolavirus'', more commonly known as Ebola virus (; EBOV), is one of six known species within the genus ''Ebolavirus''. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). Ebola virus has caused the majority of human deaths from EVD, and was the cause of the 2013–2016 epidemic in western Africa, which resulted in at least suspected cases and confirmed deaths. Ebola virus and its genus were both originally named for Zaire (now the Democratic Republic of the Congo), the country where it was first described, and was at first suspected to be a new "strain" of the closely related Marburg virus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species ''Zaire ebolavirus'', which is assigned to the genus ''Ebolavirus'', family ''Filoviridae'', order ''Mononegavirales''. The members of the species are cal ...
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Taxonomy (biology)
In biology, taxonomy () is the scientific study of naming, defining ( circumscribing) and classifying groups of biological organisms based on shared characteristics. Organisms are grouped into taxa (singular: taxon) and these groups are given a taxonomic rank; groups of a given rank can be aggregated to form a more inclusive group of higher rank, thus creating a taxonomic hierarchy. The principal ranks in modern use are domain, kingdom, phylum (''division'' is sometimes used in botany in place of ''phylum''), class, order, family, genus, and species. The Swedish botanist Carl Linnaeus is regarded as the founder of the current system of taxonomy, as he developed a ranked system known as Linnaean taxonomy for categorizing organisms and binomial nomenclature for naming organisms. With advances in the theory, data and analytical technology of biological systematics, the Linnaean system has transformed into a system of modern biological classification intended to reflect the evolu ...
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Ravn Virus
Ravn virus (; RAVV) is a close relative of Marburg virus (MARV). RAVV causes Marburg virus disease in humans and nonhuman primates, a form of viral hemorrhagic fever. RAVV is a Select agent, World Health Organization Risk Group 4 Pathogen (requiring Biosafety Level 4-equivalent containment), National Institutes of Health/National Institute of Allergy and Infectious Diseases Category A Priority Pathogen, Centers for Disease Control and Prevention Category A Bioterrorism Agent, and listed as a Biological Agent for Export Control by the Australia Group. Use of term Ravn virus (today abbreviated RAVV, but then considered identical to Marburg virus) was first described in 1987 and is named after a 15-year old Danish boy who fell ill and died from it. Today, the virus is classified as one of two members of the species '' Marburg marburgvirus'', which is included into the genus ''Marburgvirus'', family ''Filoviridae'', order ''Mononegavirales''. The name Ravn virus is derived from '' ...
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Marburg Virus
Marburg virus (MARV) is a hemorrhagic fever virus of the ''Filoviridae'' family of viruses and a member of the species '' Marburg marburgvirus'', genus ''Marburgvirus''. It causes Marburg virus disease in primates, a form of viral hemorrhagic fever. The virus is considered to be extremely dangerous. The World Health Organization (WHO) rates it as a Risk Group 4 Pathogen (requiring biosafety level 4-equivalent containment). In the United States, the National Institute of Allergy and Infectious Diseases ranks it as a Category A Priority Pathogen and the Centers for Disease Control and Prevention lists it as a Category A Bioterrorism Agent. It is also listed as a biological agent for export control by the Australia Group. The virus can be transmitted by exposure to one species of fruit bats or it can be transmitted between people via body fluids through unprotected sex and broken skin. The disease can cause haemorrhage, fever, and other symptoms similar to Ebola, which belongs t ...
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Democratic Republic Of The Congo
The Democratic Republic of the Congo (french: République démocratique du Congo (RDC), colloquially "La RDC" ), informally Congo-Kinshasa, DR Congo, the DRC, the DROC, or the Congo, and formerly and also colloquially Zaire, is a country in Central Africa. It is bordered to the northwest by the Republic of the Congo, to the north by the Central African Republic, to the northeast by South Sudan, to the east by Uganda, Rwanda, and Burundi, and by Tanzania (across Lake Tanganyika), to the south and southeast by Zambia, to the southwest by Angola, and to the west by the South Atlantic Ocean and the Cabinda exclave of Angola. By area, it is the second-largest country in Africa and the 11th-largest in the world. With a population of around 108 million, the Democratic Republic of the Congo is the most populous officially Francophone country in the world. The national capital and largest city is Kinshasa, which is also the nation's economic center. Centered on the Cong ...
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Province Orientale
Orientale Province ( French: ''Province orientale'', "Eastern province") is one of the former provinces of the Democratic Republic of the Congo and its predecessors the Congo Free State and the Belgian Congo. It went through a series of boundary changes between 1898 and 2015, when it was divided into smaller units. The District of Orientale Province was created from Stanley Falls District on 15 July 1898. The district was expanded to become Orientale Province in 1913. It was divided in 1933 into Costermansville (later Kivu) and Stanleyville Province. Stanleyville Province was renamed Orientale Province from 1947 to 1963, when it was broken up into Kibali-Ituri, Uélé and Haut-Congo provinces. Orientale Province was reconstituted in 1966. Between 1971 and 1997 it was called Haut-Zaïre, then it returned to the name of Orientale. The province contained the Bas-Uele, Haut-Uele, Ituri and Tshopo districts. These were elevated to provinces in 2015 under the 2006 constitution. Th ...
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Ebola Virus Disease
Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after becoming infected with the virus. The first symptoms are usually fever, sore throat, muscle pain, and headaches. These are usually followed by vomiting, diarrhoea, rash and decreased liver and kidney function, at which point, some people begin to bleed both internally and externally. The disease kills between 25% and 90% of those infected – about 50% on average. Death is often due to shock from fluid loss, and typically occurs between six and 16 days after the first symptoms appear. Early treatment of symptoms increases the survival rate considerably compared to late start. The virus spreads through direct contact with body fluids, such as blood from infected humans or other animals, or from contact with items that have recently been conta ...
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Nucleotide
Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth. Nucleotides are obtained in the diet and are also synthesized from common nutrients by the liver. Nucleotides are composed of three subunit molecules: a nucleobase, a five-carbon sugar (ribose or deoxyribose), and a phosphate group consisting of one to three phosphates. The four nucleobases in DNA are guanine, adenine, cytosine and thymine; in RNA, uracil is used in place of thymine. Nucleotides also play a central role in metabolism at a fundamental, cellular level. They provide chemical energy—in the form of the nucleoside triphosphates, adenosine triphosphate (ATP), guanosine triphosphate (GTP), cytidine triphosphate (CTP) and uridine triphosphate (UTP)—throughout the cell for the many cellular func ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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Article (grammar)
An article is any member of a class of dedicated words that are used with noun phrases to mark the identifiability of the referents of the noun phrases. The category of articles constitutes a part of speech. In English, both "the" and "a(n)" are articles, which combine with nouns to form noun phrases. Articles typically specify the grammatical definiteness of the noun phrase, but in many languages, they carry additional grammatical information such as gender, number, and case. Articles are part of a broader category called determiners, which also include demonstratives, possessive determiners, and quantifiers. In linguistic interlinear glossing, articles are abbreviated as . Types Definite article A definite article is an article that marks a definite noun phrase. Definite articles such as English ''the'' are used to refer to a particular member of a group. It may be something that the speaker has already mentioned or it may be otherwise something uniquely specified. ...
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Italic Type
In typography, italic type is a cursive font based on a stylised form of calligraphic handwriting. Owing to the influence from calligraphy, italics normally slant slightly to the right. Italics are a way to emphasise key points in a printed text, to identify many types of creative works, to cite foreign words or phrases, or, when quoting a speaker, a way to show which words they stressed. One manual of English usage described italics as "the print equivalent of Underline, underlining"; in other words, underscore in a manuscript directs a typesetter to use italic. The name comes from the fact that calligraphy-inspired typefaces were first designed in Italy, to replace documents traditionally written in a handwriting style called chancery hand. Aldus Manutius and Ludovico Arrighi (both between the 15th and 16th centuries) were the main type designers involved in this process at the time. Along with blackletter and Roman type, it served as one of the major typefaces in the history ...
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Capitalization
Capitalization (American English) or capitalisation (British English) is writing a word with its first letter as a capital letter (uppercase letter) and the remaining letters in lower case, in writing systems with a case distinction. The term also may refer to the choice of the casing applied to text. Conventional writing systems (orthographies) for different languages have different conventions for capitalization, for example, the capitalization of titles. Conventions also vary, to a lesser extent, between different style guides. In addition to the Latin script, capitalization also affects the Armenian, Cyrillic, Georgian and Greek alphabets. The full rules of capitalization in English are complicated. The rules have also changed over time, generally to capitalize fewer words. The conventions used in an 18th-century document will be unfamiliar to a modern reader; for instance, many common nouns were capitalized. The systematic use of capitalized and uncapitalized words in run ...
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