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BufferGel
BufferGel is the brand name of a spermicide and microbicide gel which is being tested for its potential development into a preventive medicine to stop the transmission of HIV. Testing In macaques, after BufferGel's effect on microflora Microbiota are the range of microorganisms that may be commensal, symbiotic, or pathogenic found in and on all multicellular organisms, including plants. Microbiota include bacteria, archaea, protists, fungi, and viruses, and have been found to ... and pH were measured by vaginal colposcopy and rectal lavage researchers determined that it fit the safety profile of a drug which could be tested on humans. A phase I clinical trial done on women in India, Thailand gave supporting evidence that users tolerate the drug well. A similar trial in the United States also showed drug tolerance. References External linksManufacturer's product page {{Microbicides for sexually transmitted diseases Microbicides Spermicide ...
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Spermicide
Spermicide is a contraceptive substance that destroys sperm, inserted vaginally prior to intercourse to prevent pregnancy. As a contraceptive, spermicide may be used alone. However, the pregnancy rate experienced by couples using only spermicide is higher than that of couples using other methods. Usually, spermicides are combined with contraceptive barrier methods such as diaphragms, condoms, cervical caps, and sponges. Combined methods are believed to result in lower pregnancy rates than either method alone. Spermicides are typically unscented, clear, unflavored, non-staining, and lubricative. Types and effectiveness The most common active ingredient of spermicides is nonoxynol-9. Spermicides containing nonoxynol-9 are available in many forms, such as jelly (gel), films, and foams. Used alone, spermicides have a perfect use failure rate of 6% per year when used correctly and consistently, and 16% failure rate per year in typical use. Spermicide brands This list of exampl ...
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Microbicide
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi. They can also be classified according to their function. Agents that kill microbes are microbicides, while those that merely inhibit their growth are called bacteriostatic agents. The use of antimicrobial medicines to treat infection is known as antimicrobial chemotherapy, while the use of antimicrobial medicines to prevent infection is known as antimicrobial prophylaxis. The main classes of antimicrobial agents are disinfectants (non-selective agents, such as bleach), which kill a wide range of microbes on non-living surfaces to prevent the spread of illness, antiseptics (which are applied to living tissue and help reduce infection during surgery), and antibiotics (which destroy microorganisms within the body) ...
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Microflora
Microbiota are the range of microorganisms that may be commensal, symbiotic, or pathogenic found in and on all multicellular organisms, including plants. Microbiota include bacteria, archaea, protists, fungi, and viruses, and have been found to be crucial for immunologic, hormonal, and metabolic homeostasis of their host. The term ''microbiome'' describes either the collective genomes of the microbes that reside in an ecological niche or within the microbes themselves. The microbiome and host emerged during evolution as a synergistic unit from epigenetics and genetic characteristics, sometimes collectively referred to as a holobiont. The presence of microbiota in human and other metazoan guts has been critical for understanding the co-evolution between metazoans and bacteria. Microbiota play key roles in the intestinal immune and metabolic responses via their fermentation product ( short-chain fatty acid), acetate. Introduction All plants and animals, from simple life fo ...
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Colposcopy
Colposcopy ( grc, κόλπος, kolpos, hollow, womb, vagina + ''skopos'' "look at") is a medical diagnostic procedure to visually examine the cervix as well as the vagina and vulva using a colposcope. The main goal of colposcopy is to prevent cervical cancer by detecting and treating precancerous lesions early. Human Papillomavirus (HPV) is a common infection and the underlying cause for most cervical cancers. Smoking also makes developing cervical abnormalities more likely. Other reasons for a patient to have a colposcopy include assessment of diethylstilbestrol (DES) exposure in utero, immunosuppression, abnormal appearance of the cervix or as a part of a sexual assault forensic examination. Colposcopy is done using a colposcope, which provides a magnified and illuminated view of the areas, allowing the colposcopist to visually distinguish normal from abnormal appearing tissue, such as damaged or abnormal changes in the tissue (lesions), and take directed biopsies for furt ...
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Rectal Lavage
In medicine, therapeutic irrigation or lavage ( or ) is cleaning or rinsing. Types Specific types include: * Antiseptic lavage * Bronchoalveolar lavage * Gastric lavage * Peritoneal lavage * Arthroscopic lavage * Ductal lavage * Nasal irrigation * Ear lavage *''Pulsed lavage'' is delivering an irrigant (usually normal saline) under direct pressure that is produced by an electrically powered device, and is useful in cleaning e.g. chronic wounds. See also * Vaginal douche * Enema An enema, also known as a clyster, is an injection of fluid into the lower bowel by way of the rectum.Cullingworth, ''A Manual of Nursing, Medical and Surgical'':155 The word enema can also refer to the liquid injected, as well as to a device ... References {{Medical placement and administration procedures Medical treatments ...
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Microbicides
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi. They can also be classified according to their function. Agents that kill microbes are microbicides, while those that merely inhibit their growth are called bacteriostatic agents. The use of antimicrobial medicines to treat infection is known as antimicrobial chemotherapy, while the use of antimicrobial medicines to prevent infection is known as antimicrobial prophylaxis. The main classes of antimicrobial agents are disinfectants (non-selective agents, such as bleach), which kill a wide range of microbes on non-living surfaces to prevent the spread of illness, antiseptics (which are applied to living tissue and help reduce infection during surgery), and antibiotics (which destroy microorganisms within the body). ...
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