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Bruceolide
Bruceolide is a quassinoid that has been isolated from '' Bischofia javanica''. Synthetic derivatives have shown ''in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology an ...'' antimalarial activity. References Quassinoids {{organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quassinoid
Quassinoids are degraded triterpene lactones (similar to limonoids) of the Simaroubaceae plant family grouped into C-18, C-19, C-20, C-22 and C-25 types. The prototypical member of the group, quassin, was first described in the 19th century from plants of the genus '' Quassia'' from which it gets its name. It was isolated in 1937 and its structure elucidated in 1961. They are a biologically potent class of natural products, possessing antimalarial, antifeedant, insecticidal, anti-inflammatory, and anticancer properties. The quassinoid bruceantin reached two separate phase II clinical trials in 1982 and 1983. Other quassinoids include: * Bruceanols * Bruceolide * Eurycomanone * Gutolactone Gutolactone is a chemical compound A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule c ... * Isobrucein A * Neoquassin * Nigakihe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bischofia Javanica
''Bischofia javanica'', or bishop wood, is a plant species of the family Phyllanthaceae. It and the related '' Bischofia polycarpa'' are the only two members of genus '' Bischofia'' and tribe Bischofieae. These species are distributed throughout southern and southeast Asia to Australia and Polynesia also in North America (brought to North America as a decorative plant but now considered to be an invasive species). The tree is commonly used by tigers to scratch-mark territory in the jungles of Assam where it is locally called ''uriam''. They also occur in southwestern, central, eastern, and southern China, and also Taiwan, where the indigenous people consider it a sacred tree. Uses * The dark red, dense wood is used as a building material for items ranging from furniture to bridges; it is durable but is difficult to air-dry. * The fruits are used in making wine. * The seeds, which are edible, contain 30-54% oil, which is used as a lubricant. * The bark has a high tannin conten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Derivative (chemistry)
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction. In the past, derivative also meant a compound that ''can be imagined to'' arise from another compound, if one atom or group of atoms is replaced with another atom or group of atoms, but modern chemical language now uses the term structural analog for this meaning, thus eliminating ambiguity. The term "structural analogue" is common in organic chemistry. In biochemistry, the word is used for compounds that at least theoretically can be formed from the precursor compound. Chemical derivatives may be used to facilitate analysis. For example, melting point (MP) analysis can assist in identification of many organic compounds. A crystalline derivative may be prepared, such as a semicarbazone or 2,4-dinitrophenylhydrazone (derived from aldehydes or ketones), as a simple way of verifying the identity of the original compound, assuming that a table of derivative MP values is available ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
