Brodmann Area 28
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Brodmann Area 28
Brodmann area 28 is a subdivision of the cerebral cortex defined on the basis of cytoarchitecture. It is located on the medial aspect of the temporal lobe and is part of the entorhinal cortex (Brodmann-1909). Human In humans, Brodmann area 28, and Brodmann area 34 together constitute approximately the entorhinal cortex (Brodmann-1909). Guenon Brodmann regarded the location of area 28 adjacent to the hippocampus as imprecisely represented in the illustration of the cortex of the guenon brain in Brodmann-1909. It is located on the medial aspect of the temporal lobe. Distinctive features (Brodmann-1905) The molecular layer (I) is unusually wide; the external granular layer (II) contains nests of, for the most part, multipolar cells: the external pyramidal layer (III) contains medium-sized pyramidal cells which merge with cells of the internal pyramidal layer (V); a clear cell free zone represents sublayer 5b of layer V; the multiform layer is wide and has a less clear two s ...
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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial f ...
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Pyramidal Cell
Pyramidal cells, or pyramidal neurons, are a type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala. Pyramidal neurons are the primary excitation units of the mammalian prefrontal cortex and the corticospinal tract. Pyramidal neurons are also one of two cell types where the characteristic sign, Negri bodies, are found in post-mortem rabies infection. Pyramidal neurons were first discovered and studied by Santiago Ramón y Cajal. Since then, studies on pyramidal neurons have focused on topics ranging from neuroplasticity to cognition. Structure File:GFPneuron.png, Pyramidal neuron visualized by green fluorescent protein (gfp) File:Hippocampal-pyramidal-cell.png, A hippocampal pyramidal cell One of the main structural features of the pyramidal neuron is the conic shaped soma, or cell body, after which the neuron is named. Other key structural features of the pyramidal cell are a single axon, a large apical dendr ...
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Brodmann Areas
A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. History Brodmann areas were originally defined and numbered by the German anatomist Korbinian Brodmann based on the cytoarchitectural organization of neurons he observed in the cerebral cortex using the Nissl method of cell staining. Brodmann published his maps of cortical areas in humans, monkeys, and other species in 1909, along with many other findings and observations regarding the general cell types and laminar organization of the mammalian cortex. The same Brodmann area number in different species does not necessarily indicate homologous areas. A similar, but more detailed cortical map was published by Constantin von Economo and Georg N. Koskinas in 1925. Present importance Brodmann areas have been discussed, debated, refined, and renamed exhaustively for nearly a century and remain the most ...
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List Of Regions In The Human Brain
The human brain anatomical regions are ordered following standard neuroanatomy hierarchies. Functional, connective, and developmental regions are listed in parentheses where appropriate. Hindbrain (rhombencephalon) Myelencephalon *Medulla oblongata **Medullary pyramids **Arcuate nucleus ** Olivary body *** Inferior olivary nucleus **Rostral ventrolateral medulla **Caudal ventrolateral medulla **Solitary nucleus (Nucleus of the solitary tract) **Respiratory center- Respiratory groups *** Dorsal respiratory group *** Ventral respiratory group or Apneustic centre ****Pre-Bötzinger complex **** Botzinger complex **** Retrotrapezoid nucleus **** Nucleus retrofacialis **** Nucleus retroambiguus **** Nucleus para-ambiguus ** Paramedian reticular nucleus ** Gigantocellular reticular nucleus **Parafacial zone ** Cuneate nucleus **Gracile nucleus ** Perihypoglossal nuclei *** Intercalated nucleus *** Prepositus nucleus *** Sublingual nucleus ** Area postrema **Medullary cr ...
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Brodmann Area
A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. History Brodmann areas were originally defined and numbered by the German anatomist Korbinian Brodmann based on the cytoarchitectural organization of neurons he observed in the cerebral cortex using the Nissl method of cell staining. Brodmann published his maps of cortical areas in humans, monkeys, and other species in 1909, along with many other findings and observations regarding the general cell types and laminar organization of the mammalian cortex. The same Brodmann area number in different species does not necessarily indicate homologous areas. A similar, but more detailed cortical map was published by Constantin von Economo and Georg N. Koskinas in 1925. Present importance Brodmann areas have been discussed, debated, refined, and renamed exhaustively for nearly a century and remain the most w ...
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Internal Granular Layer (cerebral Cortex)
The internal granular layer of the cortex, also commonly referred to as the granular layer of the cortex, is the layer IV in the subdivision of the mammalian cortex into 6 layers. The adjective internal is used in opposition to the external granular layer of the cortex, the term granular refers to the granule cells found here. This layer receives the afferent connections from the thalamus and from other cortical regions and sends connections to the other layers. The line of Gennari The line of Gennari (also called the "band" or "stria" of Gennari) is a band of myelinated axons that runs parallel to the surface of the cerebral cortex on the banks of the calcarine fissure in the occipital lobe. This formation is visible to the ... (occipital stripe) is also present in this layer. Cerebral cortex {{neuroanatomy-stub ...
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Multiform Layer
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the br ...
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Internal Pyramidal Layer
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the br ...
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External Pyramidal Layer
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the br ...
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Cytoarchitecture
Cytoarchitecture ( Greek '' κύτος''= "cell" + '' ἀρχιτεκτονική''= "architecture"), also known as cytoarchitectonics, is the study of the cellular composition of the central nervous system's tissues under the microscope. Cytoarchitectonics is one of the ways to parse the brain, by obtaining sections of the brain using a microtome and staining them with chemical agents which reveal where different neurons are located. The study of the parcellation of ''nerve fibers'' (primarily axons) into layers forms the subject of myeloarchitectonics (


History of the cerebral cytoarchitecture

Defining cerebral cytoarchitecture began with the advent of —the science of slicin ...
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Multipolar Cell
A multipolar neuron is a type of neuron that possesses a single axon and many dendrites (and dendritic branches), allowing for the integration of a great deal of information from other neurons. These processes are projections from the neuron cell body. Multipolar neurons constitute the majority of neurons in the central nervous system. They include motor neurons and interneurons/relaying neurons are most commonly found in the cortex of the brain and the spinal cord. Peripherally, multipolar neurons are found in autonomic ganglia. See also * Dogiel cells * Ganglion cell * Purkinje cell Purkinje cells, or Purkinje neurons, are a class of GABAergic inhibitory neurons located in the cerebellum. They are named after their discoverer, Czech anatomist Jan Evangelista Purkyně, who characterized the cells in 1839. Structure T ... * Pyramidal cell Additional images File:Blausen 0672 NeuralTissue.png, Neural tissue References External links DiagramDiagramImage {{ne ...
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External Granular Layer (cerebral Cortex)
The external granular layer of the cerebral cortex is commonly known as layer II. It is different from the internal granular layer of the cerebral cortex (commonly known as layer IV). Layer II is often grouped together with layer III and referred to as layer II/III. Layers I, II, and III are together referred to as the supragranular layers, because they are above layer IV. Brodmann has this to say about layer II: "The most inconstant or variable layers are Meynert's two so-called granular layers, layers II and IV of the basic pattern (the outer and inner granular layers). They alter their original cytoarchitectonic features so extensively during ontogeny that it is often only possible to correlate their mature structure with their primitive tectogenetic form by following the whole developmental sequence. Extreme variation, such as the disappearance or doubling of layers that we have already discussed, occur particularly in them, and their specific organisation also varies w ...
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