Bristol Infirmary
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Bristol Infirmary
The Bristol Royal Infirmary, also known as the BRI, is a large teaching hospital situated in the centre of Bristol, England. It has links with the nearby University of Bristol and the Faculty of Health and Social Care at the University of the West of England, also in Bristol. The BRI is one of nine hospitals operated by the University Hospitals Bristol and Weston NHS Foundation Trust. It is located on the same site the Bristol Royal Hospital for Children, Bristol Haematology and Oncology Centre, and Bristol Heart Institute (BHI). The Bristol Haematology and Oncology Centre has 49 beds and the Bristol Heart Institute has 107, which are not included in the main hospital's total. History Early history The Bristol Royal Infirmary was founded by public subscription in 1735, making it one of the oldest infirmaries in the United Kingdom. In 1904, Sir George White, who gave Bristol its first electric tramway service and established what was to become the Bristol Aeroplane Company, ...
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Cystic Fibrosis
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly healthy. CFTR is involved in the production of sweat, digestive fluids, and mucus. When the CFTR is not functional, secretions which are usually thin instead become thick. The condition is diagnosed by a sweat test and genetic testing. Screening of infants at bi ...
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